Intercellular Communication
Mostrando 13-24 de 154 artigos, teses e dissertações.
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13. Regulation of intercellular coupling in acute and chronic heart disease
Effective pump function of the heart depends on the precise control of spatial and temporal patterns of electrical activation. Accordingly, the distribution and function of gap junction channels are important determinants of the conduction properties of myocardium and undoubtedly play other roles in intercellular communication crucial to normal cardiac funct
Brazilian Journal of Medical and Biological Research. Publicado em: 2000-04
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14. Gap junction modulation by extracellular signaling molecules: the thymus model
Gap junctions are intercellular channels which connect adjacent cells and allow direct exchange of molecules of low molecular weight between them. Such a communication has been described as fundamental in many systems due to its importance in coordination, proliferation and differentiation. Recently, it has been shown that gap junctional intercellular commun
Brazilian Journal of Medical and Biological Research. Publicado em: 2000-04
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15. Modulation of intercellular communication by differential regulation and heteromeric mixing of co-expressed connexins
Intercellular communication may be regulated by the differential expression of subunit gap junction proteins (connexins) which form channels with differing gating and permeability properties. Endothelial cells express three different connexins (connexin37, connexin40, and connexin43) in vivo. To study the differential regulation of expression and synthesis o
Brazilian Journal of Medical and Biological Research. Publicado em: 2000-04
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16. Gap junctions in isolated rat aorta: evidence for contractile responses that exhibit a differential dependence on intercellular communication
Connexin43 (Cx43) is a major gap junction protein present in the Fischer-344 rat aorta. Previous studies have identified conditions under which selective disruption of intercellular communication with heptanol caused a significant, readily reversible and time-dependent diminution in the magnitude of a1-adrenergic contractions in is
Brazilian Journal of Medical and Biological Research. Publicado em: 2000-04
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17. Sera from chronic chagasic patients depress cardiac electrogenesis and conduction
We report results obtained with sera from 58 chronic chagasic patients that were evaluated for effects on heart rate and atrioventricular (AV) conduction in isolated rabbit hearts and screened for the presence of muscarinic and beta-adrenergic activity. We show that sera from 26 patients decreased heart rate, while 10 increased it and 22 had no effect. Addit
Brazilian Journal of Medical and Biological Research. Publicado em: 2000-04
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18. Gap junctions in cells of the immune system: structure, regulation and possible functional roles
Gap junction channels are sites of cytoplasmic communication between contacting cells. In vertebrates, they consist of protein subunits denoted connexins (Cxs) which are encoded by a gene family. According to their Cx composition, gap junction channels show different gating and permeability properties that define which ions and small molecules permeate them.
Brazilian Journal of Medical and Biological Research. Publicado em: 2000-04
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19. Potential role of the src gene product in inhibition of gap-junctional communication in NIH/3T3 cells.
The effects of the src gene on the activity of protein kinase C and intercellular communication have been studied in transformed NIH/3T3 clones isolated from soft agar following transfection with the plasmid carrying the v-src gene (psrc-11). Six transformed clones that were studied contained newly incorporated v-src genes in the genome, had an increased amo
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20. Loss of intercellular junctional communication correlates with metastatic potential in mammary adenocarcinoma cells.
A series of rat 13762NF mammary adenocarcinoma cell sublines and clones of various spontaneous pulmonary metastatic potentials from the mammary fat pads of syngeneic rats were examined for their intercellular junctional communication. Using the scrape-loading dye-transfer technique to introduce Lucifer yellow (Mr 457) into cells, we measured the abilities of
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21. Hormonal regulation of cytodifferentiation and intercellular communication in cultured granulosa cells.
Granulosa cells from immature hypophysectomized diethylstilbestrol-treated rats displayed pronounced intracellular and intercellular changes after 48 hr of exposure to follicle-stimulating hormone (FSH) in vitro. As determined by light and electron microscopy, most of the FSH-treated cells became highly aggregated and grew in multilayered clusters. Numerous
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22. Symposium II: Intercellular Communication
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23. Intercellular Communication in Leucocyte Function
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24. Mechanical stimulation and intercellular communication increases intracellular Ca2+ in epithelial cells.
Intercellular communication of epithelial cells was examined by measuring changes in intracellular calcium concentration ([Ca2+]i). Mechanical stimulation of respiratory tract ciliated cells in culture induced a wave of increasing Ca2+ that spread, cell by cell, from the stimulated cell to neighboring cells. The communication of these Ca2+ waves between cell