Interaction With Mitochondria
Mostrando 1-12 de 167 artigos, teses e dissertações.
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1. Chlorophyllin Derivatives as Photosensitizers: Synthesis and Photodynamic Properties
Two new photosensitizers (PSs) derived from copper-chlorophyllin were designed to have excitation wavelengths appropriate for the use in photodynamic therapy (PDT) and to have amphiphilic character with positive charge, which favors binding to cell membranes and walls and the intracellular localization in mitochondria. Herein we describe the synthesis and ch
J. Braz. Chem. Soc.. Publicado em: 2015-12
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2. Effects of powdery mildew infection on chloroplast and mitochondrial functions in rubber tree
Powdery mildew (Oidium heveae Steinm.) is one of the most important leaf diseases in rubber tree (Hevea brasiliensis). However, physiological and molecular processes associated with the Hevea-powdery mildew interaction are still unclear. In this study, effects of powdery mildew infection on the mitochondrial and chloroplast functions in rubber tree were comp
Trop. plant pathol.. Publicado em: 2014-06
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3. Identificação de interatores putativos envolvidos na localização de proteínas de duplo direcionamento em Arabidopsis thaliana / Identification of putative interactors involved in the localization of dual-targeted proteins in Arabidopsis thaliana
Most organellar proteins are nuclear encoded, synthesized in the cytosol and then targeted to their destination. Specific subcellular targeting is conducted by a complex machinery for the specific localization of the proteins, which includes targeting sequences, cytosolic proteins and specific organelar receptors. However, little is known about the process t
Publicado em: 2011
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4. Structure-biochemical aspects of adenine nucleotide translocase, cardiolipin and ciclophilin D on Ca2+-induced mitochondrial permeability transition / Aspectos bioquímico-estruturais do transportador de nucleotídeos de adenina, cardiolipinas e ciclofilina D na transição de permeabilidade mitocondrial induzida por Ca2+
Oxidation of the Adenine Nucleotide Translocase (ANT) cysteine residue 56 (ANT-cys56) is potentially involved in Ca2+-induced Mitochondrial Permeability Transition (MPT), a process which is prevented by cyclosporine A (CsA), due to its inhibition of Permeability Transition Pore (PTP) opener component, the peptidyl-prolyl cis-trans isomerase cyclophylin D (cy
Publicado em: 2010
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5. Tetracationic alkylated porphyrin: Photosensitizers for use in photodynamic therapy of skin cancers / Porfirinas tetracatiônicas alquiladas: sistemas porfirínicos fotossensibilizadores para uso em terapia fotodinâmica do câncer de pele
A series of photosensitizers (PS), which are meso-substituted tetra-cationic porphyrins, was synthesized and characterized in order to study the role of amphiphilicity and zinc insertion in PDT efficacy. The photophysical properties of all compounds are quite similar (absorption maxima in the same region of the spectra, f 0.02; ~0.8). An increase in lipophil
Publicado em: 2009
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6. Partial purification of tightly bound mitochondrial hexokinase from maize (Zea mays L.) root membranes
In mammals, hexokinase (HK) is strategically located at the outer membrane of mitochondria bound to the porin protein. The mitochondrial HK is a crucial modulator of apoptosis and reactive oxygen species generation. In plants, these properties related to HK are unknown. In order to better understand the physiological role of non-cytosolic hexokinase (NC-HK)
Brazilian Journal of Medical and Biological Research. Publicado em: 2006-09
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7. Porphyrins derivatives as photosensitizers for photodynamic therapy / Derivados porfirínicos como fotossensibilizadores para terapia fotodinâmica
Nesta tese serão discutidos alguns aspectos químicos, fotoquímicos e fotofísicos importantes no desenvolvimento de fotossensibilizadores para aplicação em terapia fotodinâmica (TFD). Os estudos abrangeram a investigação de 29 espécies, sendo que 20 delas continham um anel porfirínico convencional e 9 eram porfirinas duplamente N-confusas. As prime
Publicado em: 2005
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8. Led enhancement in mitochondrial oxidative phosphorylation for hepatectomized rats
Recently, the LED (light emitting diode) developed by the Optics Group of IFSC-USP has been used instead of laser for the treatment of skin tumors by the PDT (Photodinamic Therapy) because of its low operational cost compared to the use of a laser. In this paper we investigate the effect of LED light on oxidative phosphorylation during liver regeneration aft
Acta Cirurgica Brasileira. Publicado em: 2002
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9. Activity and functional interaction of alternative oxidase and uncoupling protein in mitochondria from tomato fruit
Cyanide-resistant alternative oxidase (AOX) is not limited to plant mitochondria and is widespread among several types of protists. The uncoupling protein (UCP) is much more widespread than previously believed, not only in tissues of higher animals but also in plants and in an amoeboid protozoan. The redox energy-dissipating pathway (AOX) and the proton elec
Brazilian Journal of Medical and Biological Research. Publicado em: 2000-03
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10. Estudo da interação da veratrina com o musculo esqueletico por metodos histoquimicos, ultraestruturais e bioquimicos
Veratrine, a commercial extract from the South and Central America plant Schoenocaulon officinale (Liliaceae), activates voltage-dependent Na + channels to produce persistent depolarization and an increase in sodium ion penneability in muscle fibers or nerves. The aim of this study was to investigate the effects of the veratrine aIkaloid on skeletal muscle o
Publicado em: 2000
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11. Role of Mitochondria in the Origin of Chloroplast Starch Grains: Description of the Phenomenon 12
By phase microscopic observation of living palisade parenchyma cells in sections of Nicotiana excelsior leaves from plants previously placed in the dark for 72 hours, 30 to 45 minutes of light is found to induce mitochondria to remain stationary within the concavity of the chloroplasts and become round. Extending the illumination period to 60 to 90 minutes c
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12. Interaction of a synthetic mitochondrial presequence with isolated yeast mitochondria: mechanism of binding and kinetics of import.
The mechanism of interaction of a presequence with isolated yeast mitochondria was examined. A synthetic peptide corresponding to a matrix-targeting signal was covalently labeled with a fluorescent probe. Binding of the presequence to the surface of the mitochondria and translocation of the presequence into the interior of the mitochondria could then be moni