Induction Of Nitric Oxide
Mostrando 1-12 de 332 artigos, teses e dissertações.
-
1. Hydrogen sulfide: a new endogenous player in an old mechanism of plant tolerance to high salinity
ABSTRACT High salinity affects plants due to stimulation of osmotic stress. Cell signaling triggered by nitric oxide (NO) and hydrogen sulfide (H2S) activates a cascade of biochemical events that culminate in plant tolerance to abiotic and biotic stresses. For instance, the NO/H2S-stimulated biochemical events that occur in plants during response to high sal
Acta Bot. Bras.. Publicado em: 19/10/2017
-
2. Penile alterations at early stage of type 1 diabetes in rats
ABSTRACT Objective Diabetes affects the erectile function significantly. However, the penile alterations in the early stage of diabetes in experimental animal models have not been well studied. We examined the changes of the penis and its main erectile components in diabetic rats. Materials and methods Male Sprague-Dawley rats were divided into 2 groups:
Int. braz j urol.. Publicado em: 2017-08
-
3. Tadalafil: Protective Action against the Development of Multiple Organ Failure Syndrome
Abstract Introduction: Multiple organ failure syndrome (MOFS) is a pathology associated to unspecified and severe trauma, characterized by elevated morbidity and mortality. The complex inflammatory MOFS-related reactions generate important ischemia-reperfusion responses in the induction of this syndrome. Nitric oxide elevation, through the activation of cyc
Braz. J. Cardiovasc. Surg.. Publicado em: 2017-08
-
4. Flax lignan concentrate attenuate hypertension and abnormal left ventricular contractility via modulation of endogenous biomarkers in two-kidney-one-clip (2K1C) hypertensive rats
ABSTRACT The present investigation was designed to study the effect of flax lignan concentrate obtained from Linum usitatissimum L., Linaceae, in two-kidney, one clip (2K1C) hypertension model in Wistar rats. 2K1C Goldblatt model rats were divided randomly into six groups: sham, 2K1C control, captopril (30 mg/kg), flax lignan concentrate (200, 400 and 800 mg
Rev. bras. farmacogn.. Publicado em: 2016-10
-
5. LNO3 AND L3 Are Associated With Antiproliferative And Pro-Apoptotic Action In Hepatoma Cells
Abstract The identification of antitumoral substances is the focus of intense biomedical research. Two structural analogues of thalidomide, LNO3 and L3, are two synthetic compounds that might possess such antitumor properties. We evaluated the toxicological effects of these substances, including cytotoxicity, genotoxicity and induction of apoptosis in HTC ce
Genet. Mol. Biol.. Publicado em: 2016-06
-
6. Hepatotoxicity and oxidative stress induced byNaja haje crude venom
Background Snake venoms are synthesized and stored in venom glands. Most venoms are complex mixtures of several proteins, peptides, enzymes, toxins and non-protein components. In the present study, we investigated the oxidative stress and apoptosis in rat liver cells provoked by Naja haje crude injection (LD50) after four hours.Methods Wistar rats were rando
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 02/10/2014
-
7. Inflammatory response of endothelial cells to hepatitis C virus recombinant envelope glycoprotein 2 protein exposure
The hepatitis C virus (HCV) encodes approximately 10 different structural and non-structural proteins, including the envelope glycoprotein 2 (E2). HCV proteins, especially the envelope proteins, bind to cell receptors and can damage tissues. Endothelial inflammation is the most important determinant of fibrosis progression and, consequently, cirrhosis. The a
Mem. Inst. Oswaldo Cruz. Publicado em: 09/09/2014
-
8. Ethyl-pyruvate reduces lung injury matrix metalloproteinases and cytokines and improves survival in experimental model of severe acute pancreatitis
PURPOSE: To investigate if the ethyl-pyruvate solution could reduce mortality in AP and/or diminish the acute lung injury. METHODS: Forty male rats, weighing between 270 to 330 grams were operated. An experimental model of severe AP by injection of 0.1ml/100g of 2.5% sodium taurocholate into the bilio-pancreatic duct was utilized. The rats were divided into
Acta Cir. Bras.. Publicado em: 2013-08
-
9. Sinalização da indução do metabolismo ácido das crassuláceas (CAM) por ácido abscísico e óxido nítrico em Guzmania monostachia (Bromeliaceae) / Abscisic acid and nitric oxide signaling on the induction of crassulacean acid metabolism in Guzmania monostachia (Bromeliaceae)
Guzmania monostachia é uma bromélia tanque epífita C3-CAM facultativa, constituindo-se em um modelo muito interessante para estudar a sinalização que ocorre na transição da fotossíntese C3 para CAM. Baseado em resultados obtidos pelo Laboratório de Fisiologia Vegetal do IBUSP, constatou-se que a mudança em questão se dá de forma diferente ao long
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/03/2012
-
10. Atividade imunomoduladora da ouabaína no processo inflamatório agudo / OUABAIN IMMUNOMODULATORY ACTIVITY IN THE ACUTE INFLAMMATORY PROCESS.
Ouabain (OUA), a potent inhibitor of the Na+,K+-ATPase pump, was identified as an endogenous substance of human plasma. In recent years, ouabain was shown to affect various immunological processes. Mechanisms that involve cellular differentiation, proliferation, activation and migration, as well as inflammatory mediators release, are activated during inflamm
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/02/2012
-
11. M2-polarized macrophages promote metastatic behavior of Lewis lung carcinoma cells by inducing vascular endothelial growth factor-C expression
OBJECTIVES: Tumor-associated macrophages that generally exhibit an alternatively activated (M2) phenotype have been linked to tumor progression and metastasis. However, the role of M2-polarized macrophages in the growth and metastasis of lung adenocarcinoma remains enigmatic. The aim of this study was to explore the effect of M2 macrophages on the proliferat
Clinics. Publicado em: 2012-08
-
12. Efeitos do etil-piruvato no tratamento da resposta inflamatória da lesão pulmonar na pancreatite aguda necrosante induzida em ratos. / Effects of ethyl-pyruvate in the inflammatory response of lung injury in experimental acute pancreatitis in rats.
INTRODUCTION: Severe acute pancreatitis (AP) is characterized by hemodynamic alterations and systemic inflammatory response leading to a high mortality rate. In AP the inappropriate activation of pancreatic enzymes plays an important role in pancreas autodigestion and in the inflammatory mechanisms responsible for the systemic response of the disease. Ethyl-
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/11/2011