In Vitro
Mostrando 25-36 de 56916 artigos, teses e dissertações.
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25. Long Noncoding RNA AF131217.1 Regulated Coronary Slow Flow-Induced Inflammation Affecting Coronary Slow Flow via KLF4
Abstract Introduction: This study investigated the correlation between the levels of long noncoding ribonucleic acids (lncRNAs) AF131217.1 and coronary slow flow (CSF). Methods: A total of 22 patients in the high-sensitivity C-reactive protein (hsCRP) group diagnosed with CSF from January 2018 to December 2018 were enrolled in this study. Coronary flow vel
Brazilian Journal of Cardiovascular Surgery. Publicado em: 2022
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26. Viability of pollen grains and stigma receptivity in Desert Rose
Resumo Adenium obesum (Forssk.) Roem. & Schult, conhecida popularmente como rosa-do-deserto, tem se tornado uma opção valiosa para o setor de plantas ornamentais. Na floricultura, a produção de híbridos é priorizada, para isso, o conhecimento da biologia floral e da reprodução sexuada da espécie é fundamental. Objetivou-se com o presente estudo: (1
Ornamental Horticulture. Publicado em: 2022
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27. Protective Effects of Platelet-rich plasma for in vitro Fertilization of Rats with Ovarian Failure Induced by Cyclophosphamide
Resumo Objetivo A insuficiência ovariana prematura (POI) contribui significativamente para a infertilidade feminina. A ciclofosfamida (CYC) tem efeitos adversos na foliculogênese. O plasma rico em plaquetas (PRP) é um produto autólogo rico em muitos fatores de crescimento. Avaliamos o efeito protetor do PRP na fertilização in vitro em ratas com lesã
Revista Brasileira de Ginecologia e Obstetrícia. Publicado em: 2022
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28. Antibacterial Profile in vitro and in vivo of New 1,4-Naphthoquinones Tethered to 1,2,3-1H-Triazoles Against the Planktonic Growth of Streptococcus mutans
The cariogenic processes are mainly caused by the bacterium Streptococcus mutans (S. mutans) and consist of the demineralization of the tooth that occurs when the acid production overcomes the natural repair or if a problem occurs in the last one. In this work, we performed the synthesis of twenty-one 1,4-naphthoquinones tethered to 1,2,3-1H-triazoles (8a-8k
Journal of the Brazilian Chemical Society. Publicado em: 2022
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29. ASSESSMENT OF α-AMYLASE INHIBITION ACTIVITY BY AN OPTIMIZED AND VALIDATED IN VITRO MICROSCALE METHOD
Metabolic disorders, including hyperglycemia, characterize type-2 diabetes. One of the treatment methods used for postprandial hyperglycemia includes using potential therapeutic agents to inhibit α-amylase activity. This study utilized fractional design and the simplex method to optimize in vitro microscale assay inhibition conditions using Miller’s react
Química Nova. Publicado em: 2022
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30. Acidifiers blend on digestibility, blood metabolites and performance of nursery piglets
RESUMO O objetivo deste estudo foi avaliar o efeito da inclusão de dois acidificantes (com diferentes níveis de proteção) sobre o potencial de acidificação in vitro, a digestibilidade aparente do trato total dos nutrientes da dieta, os metabólitos sanguíneos e o ganho médio diário de leitões. Foram avaliados dois acidificantes comerciais (AC1 e AC
Arquivo Brasileiro de Medicina Veterinária e Zootecnia. Publicado em: 2022
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31. Benzophenone Derivatives Showed Dual Anti-Inflammatory and Antiproliferative Activities by Inhibiting COX Enzymes and Promote Cyclin E Downregulation
Considering the promising antitumor effects of compounds with dual anti-inflammatory and antiproliferative activities, thus benzophenones analogs (2-7) were evaluated on in vivo anti-inflammatory assay and molecular docking analysis. Those with the best molecular docking results were in vitro evaluated on cyclooxygenase (COX) enzymes and tested regarding ant
Journal of the Brazilian Chemical Society. Publicado em: 2022
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32. Evaluation of different protocols for culturing mesenchymal stem cells derived from murine bone marrow
ABSTRACT Introduction: Culturing bone marrow mesenchymal stem cells (BM-MSCs) is a key point in different fields of research, including tissue engineering and regenerative medicine and studies of the bone marrow microenvironment. However, isolating and expanding murine BM-MSCs in vitro has challenged researchers due to the low purity and yield of obtained c
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
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33. In vitro Antioxidant and Anticholinesterase Activities of Ouratea fieldingiana (Gardner) Eng. Leaf Extract and Correlation with Its Phenolics Profile with an in silico Study in Relation to Alzheimer’s Disease
Ouratea fieldingiana is a native medicinal plant from Northeastern Brazil and many biological properties are due to the phenolic constituents. The objective of this work was performing the characterization of O. fieldingiana leaf constituents to correlate with antioxidant and anticholinesterase activities by in vitro and in silico studies and thus contribute
Journal of the Brazilian Chemical Society. Publicado em: 2022
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34. In vitro sperm characteristics and in vivo fertility of sex-sorted and conventional semen in suckled Nelore cows at a traditional schedule for timed-AI with estrus detection
RESUMO O estudo teve como objetivo avaliar características espermáticas in vitro e a taxa de concepção (TC) de sêmen convencional e sexado em um programa de IATF tradicional de vacas Nelore pós-parto. Todas a vacas (n=348) foram submetidas ao mesmo protocolo de IATF à base de estradiol e de progesterona. Após 48 horas da retirada do implante, foi det
Arquivo Brasileiro de Medicina Veterinária e Zootecnia. Publicado em: 2022
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35. 2-(Pyridin-4yl)benzothiazole and Its Benzimidazole-Analogue: Biophysical and in silico Studies on Their Interaction with Urease and in vitro Anti-Helicobacter pylori Activities
In this study, the interaction between benzothiazole (BTA, concentration of a drug required for 50% inhibition in vitro (IC50) = 0.77 mM) and benzimidazole (BIA, IC50 = 2.14 mM) with urease was quantitatively assessed, using UV-Vis, molecular fluorescence, and circular dichroism. The results showed that both compounds interact with urease by a static fluores
Journal of the Brazilian Chemical Society. Publicado em: 2022
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36. Dynamics of nuclear and cytoplasm maturation of bovine oocytes cultivated in vitro in medium supplemented with fulerol
RESUMO O objetivo deste estudo foi avaliar, in vitro, a dinâmica da maturação nuclear e citoplasmática de oócitos bovinos em meio MIV tradicional (TC) e suplementado com fulerol (MF50), durante 36 horas. Na maturação nuclear do TC (n=300) e do MF50 (n=270) a cada seis horas, corados com Hoechst 33342, e na citoplasmática, avaliou-se a distribuição
Arquivo Brasileiro de Medicina Veterinária e Zootecnia. Publicado em: 2022