Immunossupression
Mostrando 1-9 de 9 artigos, teses e dissertações.
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1. Assessment of T-SPOT-TB test for the diagnosis of latent tuberculosis infection in patients with psoriasis / Avaliação do teste T-SPOT.TB no diagnóstico de infecção tuberculosa latente em pacientes com psoríase
Introduction: The therapy for psoriasis was modified by the introduction of immunebiological products that allow better disease control and better quality of life for patients, but promotes increased risk forf latent tuberculosis, requiring diagnosis shortly before its establishment. Purpose: To assess the performance of T-SPOT.TB test for the diagnosis of l
Publicado em: 2010
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2. Participation of regulatory T cells (CD4+CD25+) in the immunossupression observed on paracoccidioidomycosis / Participação de celulas T regulatorias (CD4+CD25+) na imunossupressão observada em pacientes com paracoccidioidomicose
Pacientes com paracoccidioidomicose (PCM) apresentam supressão da resposta imunológica celular, caracterizada por testes de hipersensibilidade do tipo tardio negativos a antígenos do P. brasiliensis, alta taxa de apoptose de linfócitos e alta expressão de CTLA-4 (CD152) e alta produção de citocinas supressoras (IL-10 e TGF-b). Esses dados indicam a po
Publicado em: 2009
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3. Impact of vascular endothelial growth factor on monocytes derived dendritic cells maturation in vitro. / A influência do fator de crescimento endotelial vascular na maturação "in vitro" de células dendríticas derivadas de monócitos.
Células dendríticas (DCs) são as responsáveis por orquestrar a resposta imunológica adaptativa através da estimulação de células T. Na imunoterapia do câncer, as DCs são um dos principais alvos de estimulação. Entretanto a maturação anormal destas pode interferir no resultado final da resposta imune. Neste estudo, analisaram-se os efeitos caus
Publicado em: 2008
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4. Identification of differentialy express genes during the differentiation of stem cells and characterization of mesenchymal progenitor cells / Identificação de genes diferencialmente expressos durante diferenciação de células-tronco e caracterização de células progenitoras mesenquimais
Diabetes mellitus (DM) defines a number of pathologies caused by the lack or deficient action of the insulin hormone. DM1 is caused by an auto-immune attack to insulin secreting β-pancreatic cells, while DM2 is related to ageing and obesity. Pancreas and islet allo-transplantation constitute therapeutic alternatives, but severe organ shortage and the ab
Publicado em: 2008
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5. Avaliação da expressão de genes e proteínas anti- e pró-apoptóticos em pacientes com diabetes mellitus tipo 1 e esclerose múltipla submetidos ao transplante autólogo de células-tronco hematopoéticas / Evaluation of anti and proapoptotic gene and protein expression in type 1 diabetes mellitus and multiple sclerosis patients submitted to autologous hematopoietic stem cell transplantation
Type 1 diabetes mellitus (T1DM) and multiple sclerosis (MS) are inflammatory, organ-specific autoimmune diseases characterized by selective destruction of insulin-producing pancreatic -cells and central nervous system, respectively, by autoreactive B and T cells. Deregulation of apoptotic machinery is supposed to contribute to self-tolerance breakdown and au
Publicado em: 2008
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6. Distribuição de macrófagos e alterações teciduais no coração e na medula espinhal de cães inoculados com formas tripomastigotas metacíclicas ou sangüíneas da cepa Berenice-78 do Trypanosoma cruzi submetidos à imunossupressão durante a fase aguda da infecção
Trypanosoma cruzi, the causative agent of Chagas disease, affects not only cardiac and intestinal structures but also neurological structures. Experimental canine model of T. cruzi infection has been shown to mimetize the various aspects of Chagas disease. Our group has been demonstrated that the source of the inoculum (blood-BT or metacyclic trypomastigotes
Publicado em: 2007
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7. Identificação de sequencias como iniciadores ("primers") especificos para a caracterização em cultura dos sorotipos A e B de Cryptococcus neoformans pela reação em cadeia da polimerase (PCR)
1. The cryptococcosis, a cosmopolitan disease, caused by Cryptococcus neoformans , a fungus, has been known about one century. The immunossupression that occurs by the consequence with steroids treatments and other kinds of drugs, degeneratives and infectious diseases, facilitates the proliferation and the development of these infectious agents, that permit
Publicado em: 2000
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8. Funçao celular em individuos com exposição ocupacional ao mercurio
In this work some effects of mercury on the immune response were investigated. Fifty one male workers of a mercury producing plant were studied, as well as fifty one non-exposed controls. To monitor exposure we used urinary mercury levels (HgU), determined by the atomic absorption method. Phagocytosis and killing of Candida albicans and Candida pseudotropica
Publicado em: 1993
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9. Alterações imunologicas em individuos expostos ao chumbo
In thís work some effects of lead on the immune response were investigated. Sixty lead-acid battery workers were studied, as well as fifty non-exposed control individuals. To monitor exposure we used blood lead levels(PbB) as a measure of internal dose and delta-aminolevulinic acid in uríne(ALA-U) as an indicator of effect Phagocytosis and killing of Candi
Publicado em: 1992