Immunoregulation
Mostrando 1-12 de 82 artigos, teses e dissertações.
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1. Plasmacytoid dendritic cells in dermatology,
Abstract Plasmacytoid dendritic cells are part of the dendritic cells family and are a relevant link between innate and adaptive immunity. They are the most potent producers of type 1 interferon, generating antiviral response, stimulating macrophages and dendritic cells and inducing activation and migration of natural killer cells. Plasmacytoid dendritic cel
An. Bras. Dermatol.. Publicado em: 2021-02
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2. Immunoregulation in human malaria: the challenge of understanding asymptomatic infection
Asymptomatic Plasmodium infection carriers represent a major threat to malaria control worldwide as they are silent natural reservoirs and do not seek medical care. There are no standard criteria for asymptomaticPlasmodium infection; therefore, its diagnosis relies on the presence of the parasite during a specific period of symptomless infection. The antipar
Mem. Inst. Oswaldo Cruz. Publicado em: 11/12/2015
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3. Células mesenquimais humanas: bases moleculares da atividade imunorreguladora in vitro / Human mesenchymal cells: molecular bases of the immunoregulatory activity in vitro
As células tronco mesenquimais (MSC) têm capacidade imunossupressora envolvendo diferentes mecanismos. No entanto, ainda não está claro o que desencadeia as diferentes vias de imunorregulação, ou mesmo o que determina a magnitude de sua capacidade supressora. A nossa hipótese é que a intensidade da atividade supressora das MSC esteja vinculada à sua
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 14/12/2011
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4. Imunorregulação central e periférica em pacientes com Síndrome de Down e autoimunidade / Central and peripheral immunoregulation in patients with Down syndrome and autoimmunity
Introdução: A Síndrome de Down (SD) é uma doença genética de alta prevalência, com várias alterações imunológicas decorrentes da disfunção tímica associada à doença. Neste estudo, avaliou-se a associação entre presença de autoimunidade e disfunção do timo em pacientes com SD. Métodos: Foram avaliados 22 pacientes com SD (11 com autoimun
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/11/2011
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5. Impact of galectin-1 on the evolution of acute experimental Trypanosoma cruzi infection / Avaliação da participação da galectina-1 na evolução da infecção experimental aguda por Trypanosoma cruzi
Galectin-1 (Gal-1) is a -galactoside-binding protein and participates in several biological processes, including modulation of immune response. In the literature, there are several reports about the potential therapeutic use of Gal-1 for autoimmune diseases, inflammatory, degenerative and infectious diseases. However, there are few reports on the involvement
Publicado em: 2010
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6. Immunodiagnosis potential of M. tuberculosis CFP-10 for active tuberculosis / Anáilise do potencial diagnóstico do anígeno CFP-10 expresso pelo M. tuberculosis.
The use of specific antigens of M. tuberculosis is extremely important for early diagnosis of tuberculosis and to control the spread of mycobacteria in the population. The CFP-10 is an antigen that is present in M. tuberculosis, but is absent in M. bovis of BCG and environmental mycobacteria. So, the objective of this study was to determine whether the immun
Publicado em: 2010
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7. Involvement of nitric oxide and its up/down stream molecules in the immunity against parasitic infections
Nitric oxide (NO) is a potent mediator with diverse roles in regulating cellular functions and signaling pathways. The NO synthase (NOS) enzyme family consists of three major isoforms, which convey variety of messages between cells, including signals for vasorelaxation, neurotransmission and cytotoxicity. This family of enzymes are generally classified as ne
Brazilian Journal of Infectious Diseases. Publicado em: 2009-12
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8. Advances in understanding immunity to Toxoplasma gondii
Toxoplasma gondii is an important cause of clinical disease in fetuses, infants and immunocompromised patients. Since the discovery of T. gondii 100 years ago, this pathogen and the host's immune response to toxoplasmosis have been studied intensely. This has led to the development of a working model of immunity to T. gondii, and has also resulted in fundame
Memórias do Instituto Oswaldo Cruz. Publicado em: 2009-03
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9. Dendritic cells and the 60kDa heat shock protein (Hsp60): strategies for immunoregulation in the mouse immune system / Células dendríticas e a proteína de choque térmico 60KDA (HSP60): estratégias para imunorregulação do sistema imune murino
The induction of tolerance to allotransplant without the help of immunosupressive drugs is one of the major challenges in immunology. Considering the tolerogenic potential of dendritic cells and the immunoregulatory activity of Hsp60, our objective was to determine the capacity of dendritic cells (DCs) of inducing immunoregulation through the interaction wit
Publicado em: 2008
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10. Immunoregulation in the pulmonary tuberculosis human: study of extension of the pulmonary lesions. / Imunoregulação na tuberculose pulmonar humana: estudo de extensão da lesão pulmonar.
Tuberculosis (TB) is one of the infectious diseases that cause approximately 3 million deaths and 8 million of new cases, in the worldwide, annually. This infectious disease caused by Mycobacterium tuberculosis, has attracted the attention of many studies due to the high mortality and multiresistance of the bacillus. Many factors are involved in this disease
Publicado em: 2008
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11. Immune factors and immunoregulation in tuberculosis
Pathogens causing tuberculosis and other chronic infectious diseases of major public health importance commonly have complex mechanisms involved in their persistence in the host despite specific and sometimes strong immune responses. These diseases are also associated with the lack of efficient vaccines, difficult therapeutics and a high mortality rate among
Brazilian Journal of Medical and Biological Research. Publicado em: 25/10/2006
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12. Subclass restriction and polyclonality of the systemic lupus erythematosus marker antibody anti-Sm.
Anti-Sm antibodies are highly specific markers for the diagnosis of systemic lupus erythematosus (SLE). This specificity suggests that the immunoregulation of these autoantibodies would reflect fundamental immune abnormalities in this disorder. As a clue to this immunoregulation, we have investigated the isotype distribution of anti-Sm antibodies by enzyme-l