Immunomodulators
Mostrando 1-12 de 54 artigos, teses e dissertações.
-
1. Epidermolysis bullosa acquisita
Abstract Epidermolysis bullosa acquisita is a rare autoimmune disease, characterized by the synthesis of anti-collagen VII autoantibodies, the main component of hemidesmosome anchoring fibrils. The antigen-antibody binding elicits a complex inflammatory response, which culminates in the loss of dermo-epidermal adhesion of the skin and/or mucous membranes. Sk
Anais Brasileiros de Dermatologia. Publicado em: 2022
-
2. Immunomodulation of Juvenile Pacu, Piaractus mesopotamicus, by Different β(1-3)(1-6)-D glucan Products
Abstract Stress in intensive fish farming hamper immune function of fish and cause losses by disease outbreaks, a situation that can be minimized, but cannot be completely circumvented, by the use of immunomodulators. Addition of immunomodulators to aquafeeds has thus become a common practice. β-glucan (BG) is one of most studied and effective immunomodulat
Braz. arch. biol. technol.. Publicado em: 24/10/2019
-
3. Diagnosis and treatment of latent tuberculosis infection in patients undergoing treatment with immunobiologic agents: a four-year experience in an endemic area
RESUMO Objetivo: Descrever a incidência de tuberculose ativa e a ocorrência de eventos adversos do tratamento com isoniazida em pacientes diagnosticados com tuberculose latente (TBL), portadores de doenças inflamatórias crônicas e tratados com agentes imunobiológicos em uma área endêmica no Brasil. Métodos: O diagnóstico de TBL foi feito com base
J. bras. pneumol.. Publicado em: 14/10/2019
-
4. Consensus on the treatment of autoimmune bullous dermatoses: bullous pemphigoid, mucous membrane pemphigoid and epidermolysis bullosa acquisita - Brazilian Society of Dermatology
Abstract: Bullous pemphigoid, mucous membrane pemphigoid and epidermolysis bullosa acquisita are subepidermal autoimmune blistering diseases whose antigenic target is located at the basement membrane zone. Mucous membrane pemphigoid and epidermolysis bullosa acquisita can evolve with cicatricial mucosal involvement, leading to respiratory, ocular and/or dige
An. Bras. Dermatol.. Publicado em: 30/06/2019
-
5. Advances and challenges in therapeutic monoclonal antibodies drug development
The use of serum containing polyclonal antibodies from animals immunized with toxins marked the beginning of the application of antibody-based therapy in late nineteenth century. Advances in basic research led to the development of the hybridoma technology in 1975. Eleven years later, the first therapeutic monoclonal antibody (mAb) was approved, and since th
Braz. J. Pharm. Sci.. Publicado em: 08/11/2018
-
6. Factors associated with adherence to immunomodulator treatment in people with multiple sclerosis
Abstract To determine the association between factors and adherence to immunomodulator treatment in people with multiple sclerosis treated in reference centers. Cross-sectional study conducted with 188 people who used immunomodulators in three reference centers in Ceará from March to July 2012. Adherence was assessed using the Moriskscale and factors were a
Braz. J. Pharm. Sci.. Publicado em: 20/04/2017
-
7. Bullous pemphigoid associated with milia, increased serum IgE, autoantibodies against desmogleins, and refractory treatment in a young patient
Abstract: Bullous pemphigoid is a blistering autoimmune disease characterized by two hemidesmosomal proteins (anti-BP180 and 230). Pemphigus, by contrast, is characterized by two autoantibodies (anti-desmoglein 1 and 3). Coexistence of autoantibodies of bullous pemphigoid and pemphigus in a patient is rare. A 25-year-old male patient was admitted to our hosp
An. Bras. Dermatol.. Publicado em: 2017
-
8. Effectiveness and safety of topical tacrolimus monotherapy for repigmentation in vitiligo: a comprehensive literature review
Abstract Thus far, several small studies and case reports on the use of topical immunomodulators in vitiligo have been published. We undertook a comprehensive literature review, searching for studies evaluating clinical response to tacrolimus topical therapy for vitiligo. A search was performed on PubMed/Medline using the term “vitiligo”, combined with �
An. Bras. Dermatol.. Publicado em: 2016-04
-
9. Pharmacology and toxicology of diphenyl diselenide in several biological models
The pharmacology of synthetic organoselenium compounds indicates that they can be used as antioxidants, enzyme inhibitors, neuroprotectors, anti-tumor and anti-infectious agents, and immunomodulators. In this review, we focus on the effects of diphenyl diselenide (DPDS) in various biological model organisms. DPDS possesses antioxidant activity, confirmed in
Publicado em: 2010
-
10. Avaliação da atividade imunomoduladora da microplusina sobre macrófagos murinos in vitro. / Evaluation of immunomodulatory activity of microplusin in murine macrophage in vitro.
Peptídeos de defesa do hospedeiro antimicrobiano (PDHA) são componentes do sistema imune inato podem ser expressos constitutivamente ou induzidos por componentes bacterianos, citocinas, ou a combinação de ambos. Estes peptídeos possuem ação direta sobre microrganismo e são potentes imunomoduladores de células de mamíferos. A microplusina é um pept
Publicado em: 2010
-
11. Pharmacology and toxicology of diphenyl diselenide in several biological models
The pharmacology of synthetic organoselenium compounds indicates that they can be used as antioxidants, enzyme inhibitors, neuroprotectors, anti-tumor and anti-infectious agents, and immunomodulators. In this review, we focus on the effects of diphenyl diselenide (DPDS) in various biological model organisms. DPDS possesses antioxidant activity, confirmed in
Brazilian Journal of Medical and Biological Research. Publicado em: 21/08/2007
-
12. Impacto da raça e ancestralidade na apresentação e evolução da doença de Crohn no Brasil / The impact of race and ancestry in the presentation and progression of Crohns disease in Brazil
INTRODUCTION: Crohns disease (CD) is increasingly recognized in diverse ethnic populations. Ethnic factors related do CD are highly controversial. Apparently, there seems to be a higher incidence among white subjects. However, studies conducted in USA have shown an increase in prevalence among black subjects in the last 30 years. Overall, there is lack of in
Publicado em: 2007