Immunohistochemistry
Mostrando 13-24 de 1892 artigos, teses e dissertações.
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13. Wnt3a but not CDX-2 expression is associated with differentiated thyroid cancer
SUMMARY OBJECTIVE: Thyroid neoplasm incidence has increased worldwide, mostly due to the advancements in medical imaging and screening rates. The aberrant Wnt/β-catenin pathway has been identified as a key mechanism, and it has also been related to the metastatic activity of differentiated thyroid cancer. We aimed to verify the difference in the expression
Revista da Associação Médica Brasileira. Publicado em: 2022
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14. Blastoid mantle cell lymphoma: cutaneous infiltration
Abstract Mantle cell lymphoma is an aggressive B-cell, non-Hodgkin’s lymphoma, with lymph node or extranodal origin, and a mean survival of three to five years. Skin involvement is rare, secondary and indicates neoplasia dissemination. The authors report a case of a female patient, 69 years old, diagnosed previously, after lymph node and bone marrow biopsy
An. Bras. Dermatol.. Publicado em: 2021-08
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15. Tacrolimus action pathways in an ointment base for hypertrophic scar prevention in a rabbit ear model
Abstract Background: Tacrolimus is used to prevent unaesthetic scars due to its action on fibroblast activity and collagen production modulation. Objectives: To evaluate the action pathways, from the histopathological point of view and in cytokine control, of tacrolimus ointment in the prevention of hypertrophic scars. Methods: Twenty-two rabbits were sub
An. Bras. Dermatol.. Publicado em: 2021-08
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16. Cutaneous leiomyosarcoma: a 20-year retrospective study and review of the literature
Abstract Background: Cutaneous leiomyosarcoma is a rare malignant neoplasm with muscular origin, representing 2%-3% of all cutaneous soft tissue sarcomas. Objectives: The aim of this study was to characterize clinicopathological features of patients diagnosed with cutaneous leiomyosarcoma in our center over the last 20-years. Methods: A retrospective stud
An. Bras. Dermatol.. Publicado em: 2021-06
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17. Case for diagnosis. Dorsal nodule in a 10-year-old male,
Abstract Granular cell tumors (GCTs) are rare soft-tissue neoplasms. GCT immunohistochemistry is positive for S-100, NSE, and CD68. This report describes the case of a 10-year-old male who presented with a dorsal nodule. A biopsy revealed aggregates and sheets of large epithelioid and spindle cells. The cells had abundant eosinophilic granular cytoplasm. Imm
An. Bras. Dermatol.. Publicado em: 2021-03
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18. Cutaneous smooth muscle tumors associated with Epstein-Barr virus in an adult patient with HIV,
Abstract Epstein Barr virus-associated smooth muscle tumors are an uncommon neoplasm that occurs in immunosuppressed patients of any age. Usually, it presents as multifocal tumors mainly in the spinal cord, epidural region, gastrointestinal tract and liver, upper respiratory tract and skin, the latest with few cases reported in the literature and related wit
An. Bras. Dermatol.. Publicado em: 2021-03
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19. Local tissue reaction and histopathological characteristics of three different bulking agents: a rabbit model
ABSTRACT Purpose: We assessed the efficacy and safety of a single injection of three bulking agents over the short- and long-term follow-ups in rabbits. Dermal and preputial matrices were compared with Deflux (DxHA) injection. Material and methods: Twenty-four rabbits were divided into three groups. Group I (n=8) underwent the injection of a lyophilized de
Int. braz j urol.. Publicado em: 2021-03
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20. Immunohistochemical and clinicopathologic features of estrogen receptor-negative, progesterone receptor-positive, HER-2 negative breast carcinomas
SUMMARY OBJECTIVE: Currently, there is an ongoing debate whether progesterone receptor positive and estrogen receptor negative breast carcinomas represent a true distinct subtype of tumor or a mere immunohistochemical artifact. In this study, we conducted an immunohistochemistry panel with the antibodies TFF1, EGFR, and CK5 to reclassify this phenotype in a
Rev. Assoc. Med. Bras.. Publicado em: 2021-02
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21. Does Decreased SNX10 Serve as a Novel Risk Factor in Atrial Fibrillation of the Valvular Heart Disease? - A Case-Control Study
Abstract Introduction: Atrial fibrillation (AF) is the most common sustained arrhythmia. Sorting nexin 10 (SNX10) has been reported to be an important regulator in embryonic development and human diseases, however, little is known about its role in cardiac disease. The aim of this study was to investigate the clinical significance of SNX10 expression in AF.
Braz. J. Cardiovasc. Surg.. Publicado em: 2021-02
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22. The association between the histopathological features and microsatellite instability in young patients with urothelial carcinoma of the bladder
SUMMARY OBJECTIVE: Bladder cancer under the age of 40 is extremely rare. Bladder cancer development involves complex and multi-stage processes, one of which is the DNA damage repair mechanism. In this retrospective study, we aimed to evaluate the histopathological features of bladder urothelial carcinoma seen in patients under 40 years of age and tumor micr
Rev. Assoc. Med. Bras.. Publicado em: 2021-01
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23. Tumor in the plantar region: dermatofibrosarcoma protuberans in an infrequent topography,
Abstract Dermatofibrosarcoma protuberans is a rare mesenchymal tumor; it is locally aggressive and presents high rates of local recurrence. It may present as a nodular or plaque vegetating lesion. It mainly affects the trunk and proximal limbs, being rare in the distal extremities. Biopsy and immunohistochemistry help confirm the diagnosis. The authors repor
An. Bras. Dermatol.. Publicado em: 2020-12
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24. O que esperar da nova proposta de reforma administrativa: uma análise da Proposta de Emenda à Constituição (PEC) 32/20
Abstract Background The importance of regional sympathetic denervation in the pathophysiology and prognosis of Chagas disease has been recognized. Objective To conduct a review of studies that have assessed dysautonomia in chronic Chagas heart disease. Methods The search was performed on the Medline, Pubmed, Lilacs and SciELO databases. The inclusion c
Rev. Adm. Pública. Publicado em: 2020-12