Immune Tolerance
Mostrando 1-12 de 348 artigos, teses e dissertações.
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1. Mild and asymptomatic cases of COVID-19 are potential threat for faecal–oral transmission
SUMMARY Checkpoint inhibitors have substantially improved the prognosis for patients with advanced malignancy. Treatment with immunomodulants has the ability to reactivate the immune system against tumor cells, but can also trigger the development of immune-related adverse events that reflects a loss of tolerance of the immune system for self-antigens. Regar
Braz J Infect Dis. Publicado em: 2020-08
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2. Permanent diabetes insipidus in a patient with mesothelioma treated with immunotherapy
SUMMARY Checkpoint inhibitors have substantially improved the prognosis for patients with advanced malignancy. Treatment with immunomodulants has the ability to reactivate the immune system against tumor cells, but can also trigger the development of immune-related adverse events that reflects a loss of tolerance of the immune system for self-antigens. Regar
Arch. Endocrinol. Metab.. Publicado em: 2020-08
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3. CD4+CD69+ T cells and CD4+CD25+FoxP3+ Treg cells imbalance in peripheral blood, spleen and peritoneal lavage from pristane-induced systemic lupus erythematosus (SLE) mice
Abstract Background: Adaptive immune cells, including CD4+CD69+ and CD4+CD25+FoxP3+ regulatory T (Treg) cells, are important for maintaining immunological tolerance. In human systemic lupus erythematosus (SLE), CD4+CD25+FoxP3+ Treg cells are reduced, whereas CD69 expression is increased, resulting in a homeostatic immune imbalance that may intensify autorea
Adv. rheumatol.. Publicado em: 05/08/2019
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4. No fitness costs are induced by Spiroplasma infections of Aphis citricidus reared on two different host plants
Resumo Pulgões podem abrigar vários simbiontes secundários que alteram características ecológicas importantes, como defesa contra inimigos naturais, tolerância ao calor e utilização da planta hospedeira. Um desses simbiontes secundários, Spiroplasma, é estudado em Drosophila por alterar a razão sexual e interagir com o sistema imunológico do hosp
Braz. J. Biol.. Publicado em: 04/07/2019
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5. Gut: Key Element on Immune System Regulation
Abstract The gut is the main organ that mediates the contact between antigens with our organism, controlling the immune response against environmental factors, such as microbiota and food. Innate lymphoid cells participate in the gut-associated lymphoid tissue (GALT) maturation during the prenatal and early postnatal periods. After birth, breast milk provide
Braz. arch. biol. technol.. Publicado em: 13/06/2019
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6. Reaction of strawberry cultivars to root-knot and root-lesion nematodes
RESUMO Considerando a importância econômica da cultura do morangueiro no Brasil, com tendência clara de migração da produção no solo para sistemas inovadores de produção em substratos, é fundamental a avaliação das cultivares disponíveis no mercado quanto a tolerância a patógenos com potencial de infestação. Avaliou-se a resistência de oito
Hortic. Bras.. Publicado em: 15/04/2019
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7. Inulin Induces IL-10 Secretion and Increased FOXP3 Gene Expression in Human Peripheral Blood Mononuclear Cells
ABSTRACT Inulin is an effective prebiotic and its potential in modulating systemic immunity have been proposed. A subpopulation of T cells, named T regulatory cells (Tregs), expressing the Forkhead boxP3 transcription factor are key mediators of peripheral tolerance and suppress undesirable immune responses. These Tregs can be induced by cytokine transformin
Braz. arch. biol. technol.. Publicado em: 29/10/2018
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8. Dendritic cells and their relation to apical peridontitis
Abstract: The purpose of this manuscript was to re-discuss apical periodontitis, apical biofilm, and its possible relationship with dendritic cells (DC). DCs are potent regulators of the immune system and their function is divided into three categories that involve the presentation of antigens: the presentation of antigens and activation of T cells; a not we
Braz. oral res.. Publicado em: 18/10/2018
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9. Imbalanced expression of functional surface molecules in regulatory and effector T cells in systemic lupus erythematosus
Regulatory T (TREG) cells play an important role in maintaining immune tolerance and avoiding autoimmunity. We analyzed the expression of membrane molecules in TREG and effector T cells in systemic lupus erythematosus (SLE). TREG and effector T cells were analyzed for the expression of CTLA-4, PD1, CD28, CD95, GITR, HLA-DR, OX40, CD40L, and CD45RO in 26 pati
Braz J Med Biol Res. Publicado em: 2014-08
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10. Vascular endothelial growth factor-A enhances indoleamine 2,3-dioxygenase expression by dendritic cells and subsequently impacts lymphocyte proliferation
Dendritic cells (DCs) are antigen (Ag)-presenting cells that activate and stimulate effective immune responses by T cells, but can also act as negative regulators of these responses and thus play important roles in immune regulation. Pro-angiogenic vascular endothelial growth factor (VEGF) has been shown to cause defective DC differentiation and maturation.
Mem. Inst. Oswaldo Cruz. Publicado em: 09/10/2013
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11. Condicionantes sociais na delimitação de espaços endêmicos de hanseníase / Social conditions in the delimitation of areas endemic for leprosy
INTRODUÇÃO: A hanseníase é uma doença infecciosa crônica granulomatosa, cujo agente etiológico é uma bactéria de vida intracelular obrigatória, o Mycobacterium leprae, que tem no homem seu principal reservatório. A doença possui distribuição universal, predominando atualmente, em latitudes tropicais e tem sido enquadrada entre as enfermidades n
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/09/2012
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12. Avaliação de viabilidade, tolerância e segurança da vacina com células dendríticas autológas maduras em pacientes com carcinoma de pulmão não pequenas células avançado = : Assessment of feasibility, safety and tolerance of mature autologous dendritic cells vaccine in patients with advanced non-small cell lung carcinoma / Assessment of feasibility, safety and tolerance of mature autologous dendritic cells vaccine in patients with advanced non-small cell lung carcinoma
Os resultados terapêuticos globais do carcinoma de pulmão não pequenas células em estádio avançado são bem limitados. A imunoterapia com células dendríticas foi desenvolvida como uma nova estratégia para o tratamento de câncer de pulmão. O objetivo deste estudo foi avaliar a viabilidade, segurança e respostas imunológicas em pacientes com carci
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/06/2012