Idiopathic Short Stature
Mostrando 1-12 de 14 artigos, teses e dissertações.
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1. Correlation of body mass index to Ghrelin and IGF-1 among children with short stature
Abstract Objective: To assess the BMI among children with Growth Hormone Deficiency (GHD) and Idiopathic Short Stature (ISS) and its correlation to ghrelin, Growth Hormone (GH), and Insulin-like Growth Factor-1 (IGF-1) levels. Methods: A cross-sectional descriptive study in which 42 patients attending the Pediatric endocrine clinic were enrolled, allocated
Jornal de Pediatria. Publicado em: 2022
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2. An Investigation of Hearing (250-20,000 Hz) in Children with Endocrine Diseases and Evaluation of Tinnitus and Vertigo Symptoms
Abstract Introduction Despite much advancement in medicine, endocrine and metabolic diseases remain an important cause of morbidity and even mortality in children. Objective The present study was planned to investigate the evaluation of hearing that also includes high frequencies, and the presence and degree of vertigo and tinnitus symptoms in pediatric
Int. Arch. Otorhinolaryngol.. Publicado em: 2020-06
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3. Clonidine-stimulated growth hormone concentrations (cut-off values) measured by immunochemiluminescent assay (ICMA) in children and adolescents with short stature
OBJECTIVES: To establish cut-off values for growth hormone concentrations using clonidine as a secretagogue and an immunochemiluminescent assay as the method of measurement and to analyze the response time as well as the influence of gender, nutritional status and pubertal stage. METHODS: A total of 225 tests were performed in 3 patient groups, categorized
Clinics. Publicado em: 2016-04
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4. Reported shoes size during GH therapy: is foot overgrowth a myth or reality?
Objectives To describe population reference values for shoes size, and to identify possible disproportional foot growth during GH therapy.Materials and methods Construction of percentile chart based on 3,651 controls (male: 1,838; female: 1,813). The GH treated group included 13 children with idiopathic short stature (ISS) and 50 children with normal height,
Arch. Endocrinol. Metab.. Publicado em: 24/07/2015
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5. EFEITO DO TRATAMENTO COM HORMÔNIO DE CRESCIMENTO NA BAIXA ESTATURA IDIOPÁTICA COM DEFICIÊNCIA MODERADA DO GH OU INSENSIBILIDADE PARCIAL AO GH. / EFFECT OF THE TREATMENT WITH GROWTH HORMONE IN IDIOPATHIC SHORT STATURE WITH MODERATE GH DEFICIENCY OR PARTIAL GH INSENSITIVITY.
A baixa estatura idiopática é um conjunto heterogêneo de condições sem evidentes alterações hormonais ou etiologias definidas. Pode incluir a insensibilidade parcial ao GH (IPGH) e a deficiência moderada de GH (DMGH), ambas com concentrações baixas de fator de crescimento semelhante à insulina tipo I (IGF-I) e hiper ou sub-resposta do GH aos teste
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 01/06/2012
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6. Investigação de alterações nos genes short stature homeobox e receptor do hormônio de crescimento em pessoas com baixa estatura idiopática no Distrito Federal
A baixa estatura é uma condição que afeta 2,3% da população. Dentro deste grupo, encontra-se a Baixa Estatura Idiopática (BEI), definida como estatura inferior a 2 desvio-padrões (SD) da altura média correspondente a uma determinada idade, sexo e grupo populacional sem nenhuma outra anomalia esquelética ou sistêmica, distúrbios endócrinos, nutric
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/03/2012
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7. Pesquisa de mutações no gene do receptor do secretagogo de hormônio de crescimento (GHSR) em crianças com baixa estatura idiopática e deficiência isolada de hormônio de crescimento / Growth hormone secretatogue receptor gene (GHSR) analysis in patients with idiopathic short stature (ISS) and patients with isolated growth hormone deficiency
A ghrelina, hormônio secretado principalmente por células gástricas, liga-se ao seu receptor, o receptor de secretagogo de GH (GHSR - Growth hormone secretagogue receptor), localizado no hipotálamo e na hipófise, estimulando a síntese e secreção do GH. Recentemente foram identificadas mutações no gene GHSR em crianças com baixa estatura idiopátic
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 10/10/2011
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8. Identification of SHOX gene deletions: comparison of FISH technique, microsatellites analysis and MLPA / Identificação de deleções do gene SHOX: comparação das técnicas de FISH, análise de microssatélites e MLPA
The SHOX gene (short stature homeobox containing gene), expressed at high levels in osteogenic cells, is essential for bone development and growth process. SHOX haploinsufficiency is responsible for several phenotypes involving short stature, such as Turner syndrome, Léri-Weill dyschondrosteosis (LWD) and idiopathic short stature. Deletions are responsible
Publicado em: 2009
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9. Evaluation of calcium and vitamin D intake and biochemical parameters of the bone metabolism in patients with idiopathic short stature
Publicado em: 2008
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10. Study of the PTPN11 gene in Noonan syndrome patients and children with idiopathic short stature / "Estudo do gene PTPN11 em pacientes com a síndrome de Noonan e crianças com baixa estatura idiopática"
Noonan syndrome (NS), characterized by short stature, dysmorphic facial and thoracic features and congenital heart disease, was associated to PTPN11 gene. We studied the PTPN11 in patients with NS, parents of mutation-positive NS patients and idiopathic short stature children with signs related to NS without fulfilling the diagnostic criteria. We found misse
Publicado em: 2005
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11. DoenÃa celÃaca como causa de baixa estatura em crianÃas e adolescentes
Objective: Masters dissertation presented in the form of a review and original article with the objective of knowing the positive frequency of serological markers of the Celiac Disease in children and adolescents with short stature. Methods: A review of short stature was made as clinical presentation of the celiac disease. A bibliographical survey of literat
Publicado em: 2005
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12. Identification of a Major Recombination Hotspot in Patients with Short Stature and SHOX Deficiency
Human growth is influenced not only by environmental and internal factors but also by a large number of different genes. One of these genes, SHOX, is believed to play a major role in growth, since defects in this homeobox-containing gene on the sex chromosomes lead to syndromal short stature (Léri-Weill dyschondrosteosis, Langer mesomelic dysplasia, and Tur
American Society of Human Genetics.