Hypoxic Ischemic Brain
Mostrando 1-12 de 26 artigos, teses e dissertações.
-
1. Newborns at high risk for brain injury: the role of the amplitude-integrated electroencephalography
Abstract Objective: Amplitude-integrated electroencephalography (aEEG) is a simplified bedside neurophysiology tool that has been implemented in the neonatal intensive care unit and studied in an extensive range of clinical applications in the past decade. This critical review aimed to evaluate a variety of clinical applications of aEEG monitoring in diagno
Jornal de Pediatria. Publicado em: 2022
-
2. Selective head cooling and whole body cooling as neuroprotective agents in severe perinatal asphyxia
RESUMO INTRODUÇÃO A possibilidade de a hipotermia ter um papel terapêutico durante ou após a reanimação da asfixia perinatal grave tem sido um foco de pesquisa de longa data. Estudos desenhados em torno desse fato mostraram que a hipotermia cerebral moderada, iniciada o mais cedo possível, tem sido associada à neuroproteção potente e duradoura em
Rev. Assoc. Med. Bras.. Publicado em: 12/09/2019
-
3. Effects of hyperbaric oxygen and nerve growth factor on the long-term neural behavior of neonatal rats with hypoxic ischemic brain damage
Abstract Purpose: To evaluate the effects of HBO (Hyperbaric oxygen) and NGF (Nerve growth factor) on the long-term neural behavior of neonatal rats with HIBD (Neonatal hypoxic ischemic brain damage). Methods: The HIBD model was produced by ligating the right common carotid artery of 7 days old SD (Sprague-Dawley) rats followed by 8% O2 + 92% N2 for 2h. To
Acta Cir. Bras.. Publicado em: 2017-04
-
4. Brain caspase-3 and intestinal FABP responses in preterm and term rats submitted to birth asphyxia
Neonatal asphyxia can cause irreversible injury of multiple organs resulting in hypoxic-ischemic encephalopathy and necrotizing enterocolitis (NEC). This injury is dependent on time, severity, and gestational age, once the preterm babies need ventilator support. Our aim was to assess the different brain and intestinal effects of ischemia and reperfusion in n
Braz J Med Biol Res. Publicado em: 23/06/2016
-
5. Effect of hyperbaric oxygenation on mitochondrial function of neuronal cells in the cortex of neonatal rats after hypoxic-ischemic brain damage
The timing and mechanisms of protection by hyperbaric oxygenation (HBO) in hypoxic-ischemic brain damage (HIBD) have only been partially elucidated. We monitored the effect of HBO on the mitochondrial function of neuronal cells in the cerebral cortex of neonatal rats after HIBD. Neonatal Sprague-Dawley rats (total of 360 of both genders) were randomly divide
Braz J Med Biol Res. Publicado em: 26/04/2016
-
6. Association of NOS3 gene variants and clinical contributors of hypoxic-ischemic encephalopathy
The aim of this study was to analyze the association of different clinical contributors of hypoxic-ischemic encephalopathy with NOS3 gene polymorphisms. A total of 110 children with hypoxic-ischemic encephalopathy and 128 control children were selected for this study. Association of gender, gestational age, birth weight, Apgar score, cranial ultrasonography,
Braz J Med Biol Res. Publicado em: 15/08/2014
-
7. Decreased levels of pNR1 S897 protein in the cortex of neonatal Sprague Dawley rats with hypoxic-ischemic or NMDA-induced brain damage
Our objective was to investigate the protein level of phosphorylated N-methyl-D-aspartate (NMDA) receptor-1 at serine 897 (pNR1 S897) in both NMDA-induced brain damage and hypoxic-ischemic brain damage (HIBD), and to obtain further evidence that HIBD in the cortex is related to NMDA toxicity due to a change of the pNR1 S897 protein level. At postnatal day 7,
Braz J Med Biol Res. Publicado em: 2012-10
-
8. Respostas de recuperação tecidual no cerebelo e córtex de filhotes expostos às crises convulsivas maternas / Response of tissue recovery in cerebellum and córtex of pups exposed to maternal seizures.
Objective: This study aimed to examine possible changes arising of hypoxic-ischemic insults in brain regions such as cerebellum and cortex at different stages of postnatal development of pups subjected to maternal seizures during intrauterine life. Methods: Wistar rats were subjected to the model of epilepsy induced by pilocarpine, mated and the seizure freq
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 25/05/2011
-
9. GM1 improves neurofascin155 association with lipid rafts and prevents rat brain myelin injury after hypoxia-ischemia
White matter injury characterized by damage to myelin is an important process in hypoxic-ischemic brain damage (HIBD). Because the oligodendrocyte-specific isoform of neurofascin, neurofascin 155 (NF155), and its association with lipid rafts are essential for the establishment and stabilization of the paranodal junction, which is required for tight interacti
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-06
-
10. Prevalence of perinatal asphyxia and hypoxic-ischemic encephalopathy in term newborns considering two diagnostic criteria and the type of obstetric assistance / Prevalência de asfixia perinatal e encefalopatia hipóxico-isquêmica em recém-nascidos de termo considerando dois critérios diagnósticos e o tipo de assistência obstétrica
INTRODUÇÃO: A asfixia perinatal é uma das principais causa de óbito nos recémnascidos (RN) de termo acima de 2500g no Brasil, sendo também a causa mais importante de encefalopatia e lesão cerebral permanente em crianças. Não existindo ainda um consenso acerca de qual seria o melhor critério para seu diagnóstico. OBJETIVOS: Verificar a prevalência
Publicado em: 2008
-
11. Analise da correlação entre o tono muscular, força muscular e as funções motoras em crianças com paralisia cerebral tetraparetica espastica devido a lesões hipoxico- isquemicas
Cerebral palsy (CP) is a clinical picture resulting from nonprogressive aggression of the developing brain, characterized by tonus, muscular strength and motor function alterations. The objective ofthis study was to ana1yzethe tonus and muscular strength interference on motor functions of children with spastic tetraparetic cerebral palsy due to hypoxic ische
Publicado em: 2003
-
12. Hypoxic and ischemic hypoxia exacerbate brain injury associated with metabolic encephalopathy in laboratory animals.
Hypoxemia is a major comorbid factor for permanent brain damage in several metabolic encephalopathies. To determine whether hypoxia impairs brain adaptation to hyponatremia, worsening brain edema, we performed in vitro and in vivo studies in cats and rats with hyponatremia plus either ischemic or hypoxic hypoxia. Mortality with hypoxic hypoxia was 0%; with h