Hypoglycemic Agents
Mostrando 13-24 de 26 artigos, teses e dissertações.
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13. AvaliaÃÃo dos efeitos antiinflamatÃrio, hipoglicemiante e hipolipemiante da lovastatina em roedores / EVALUATION OF HIPOGLICEMIC AND ANTIINFLAMMATORY ACTIONS OF LOVASTATIN IN RODENTS
Os efeitos antiinflamatÃrio, hipoglicemiante e hipolipemiante da lovastatina foram avaliados sobre os modelos da peritonite e edema de pata induzidos por carragenina 1% e modelo de diabetes mellitus induzida por aloxano. A lovastatina reduziu o edema de pata, expresso em mL, induzido por carragenina 1% com as doses de 2, 5 e 10 mg/kg na 2Â h (1,33 Â 0,12;
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 09/06/2008
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14. The effect of repaglinide on ischemic preconditioning / Efeito da repaglinida sobre o pré-condicionamento isquêmico
Background: The increase of tolerance to myocardial ischemia observed during the second of two sequential exercise tests, the warm-up phenomenon, has been proposed as a clinical model of ischemic preconditioning. Blockers of K-ATP channels, such as the Sulfonylurea drugs, can induce loss of ischemic preconditioning, what could be involved in an increase of c
Publicado em: 2007
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15. A associação entre o perfil clínico e psicossocial de pessoas com diabetes mellitus usuárias de uma unidade de saúde da família de Sorocaba - SP / The connection between the clinical and psychosocial profile of diabetes mellitus in a health family unit users Sorocaba - SP
Diabetes Mellitus (DM) is a chronic disease responsible for the high unhealthy and mortality indicators. Although several attempts of interventions have been done to control the disease and take in the chronic disorder incidence, the issues are very fearful. The primary attention of health is essential for diabetic´s accompaniment (DM), especially on The Fa
Publicado em: 2007
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16. Non-obese adult onset diabetes with oral hypoglycemic agent failure: islet cell autoantibodies or reversible beta cell refractoriness?
Pancreatic ß cell function and insulin sensitivity, analyzed by the homeostasis model assessment, before and after 24 weeks of insulin therapy were studied and correlated with the presence of autoantibodies against ß cells (islet cell and anti-glutamic acid decarboxylase antibodies), in a group of 18 Brazilian lean adult non-insulin-dependent diabetes mell
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-10
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17. Hypertensive diabetic patients: guidelines for conduct and their difficulties
OBJECTIVE: To assess the effect of blood pressure (BP) control and other cardiovascular risk factors in patients with diabetes mellitus in a referral service for the treatment of hypertension. METHODS: A retrospective study where diabetic patients (at least 2 fasting glucose levels above 126 mg/dL, use of hypoglycemic agents or insulin, or both of these) wer
Arquivos Brasileiros de Cardiologia. Publicado em: 2003-08
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18. The effects of 2,3-diphosphoglycerate, adenosine triphosphate, and glycosylated hemoglobin on the hemoglobin-oxygen affinity of diabetic patients
The position of the oxygen dissociation curve (ODC) is modulated by 2,3-diphosphoglycerate (2,3-DPG). Decreases in 2,3-DPG concentration within the red cell shift the curve to the left, whereas increases in concentration cause a shift to the right of the ODC. Some earlier studies on diabetic patients have reported that insulin treatment may reduce the red ce
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-06
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19. Acute effect of different antidepressants on glycemia in diabetic and non-diabetic rats
Diabetic patients have a 20% higher risk of depression than the general population. Treatment with antidepressant drugs can directly interfere with blood glucose levels or may interact with hypoglycemic agents. The treatment of depression in diabetic patients must take into account variations of glycemic levels at different times and a comparison of the avai
Brazilian Journal of Medical and Biological Research. Publicado em: 2001-01
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20. Glycemic Variability Correlates Strongly With Postprandialβ-Cell Dysfunction in a Segment of Type 2 Diabetic Patients Using Oral Hypoglycemic Agents
American Diabetes Association.
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21. Rosiglitazone Is Associated with Mortality in Chronic Hemodialysis Patients
Recent studies have associated rosiglitazone, a thiazolidinedione drug, with adverse cardiovascular outcomes in the general population with diabetes. Using data from the Dialysis Outcomes and Practice Patterns Study in the United States, we examined cardiovascular hospitalization and mortality associated with prescription of rosiglitazone, compared with othe
American Society of Nephrology.
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22. Direct in vitro effect of a sulfonylurea to increase human fibroblast insulin receptors.
We have studied the effects of the oral sulfonylurea agent glyburide to modulate insulin receptors on nontransformed human fibroblasts in tissue culture. When glyburide was added to monolayers of human fibroblasts, a dose-dependent increase in the number of cell surface receptors was observed with a maximum effect (19% increase) seen at 1 microgram/ml glybur
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23. β-Cell-Specific Overexpression of Glutathione Peroxidase Preserves Intranuclear MafA and Reverses Diabetes in db/db Mice
Chronic hyperglycemia causes oxidative stress, which contributes to damage in various tissues and cells, including pancreatic β-cells. The expression levels of antioxidant enzymes in the islet are low compared with other tissues, rendering the β-cell more susceptible to damage caused by hyperglycemia. The aim of this study was to investigate whether increa
The Endocrine Society.
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24. Differential regulation of two distinct glucose transporter species expressed in 3T3-L1 adipocytes: effect of chronic insulin and tolbutamide treatment.
The HepG2-type glucose transporter (HepG2-GT) is expressed in 3T3-L1 fibroblasts and adipocytes. In contrast, the acutely insulin-regulatable glucose transporter (IRGT) is expressed only in the adipocytes. In the present study, the expression of the IRGT was shown to increase in parallel with the acquisition of acutely insulin-stimulated glucose uptake durin