Hypertension L Name
Mostrando 1-12 de 47 artigos, teses e dissertações.
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1. Electrocardiographic Abnormalities in Hypertension Models
Abstract Background: Hypertensive condition can lead to abnormalities in heart structure and electrical activity. The electrocardiogram (ECG) is a recording of the electrical activity of the heart and widely used to diagnose and detect heart problem. Objective: We conducted a comparative ECG analysis between two hypertension models (L-NAME and SHR) and the
Int. J. Cardiovasc. Sci.. Publicado em: 2020-07
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2. Possible mechanisms involved in the vasorelaxant effect produced by clobenzorex in aortic segments of rats
Clobenzorex is a metabolic precursor of amphetamine indicated for the treatment of obesity. Amphetamines have been involved with cardiovascular side effects such as hypertension and pulmonary arterial hypertension. The aim of the present study was to investigate whether the direct application of 10–9–10–5 M clobenzorex on isolated phenylephrine-precont
Braz J Med Biol Res. Publicado em: 07/08/2017
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3. Swimming training prevents coronary endothelial dysfunction in ovariectomized spontaneously hypertensive rats
Estrogen deficiency and hypertension are considered major risk factors for the development of coronary heart disease. On the other hand, exercise training is considered an effective form to prevent and treat cardiovascular diseases. However, the effects of swimming training (SW) on coronary vascular reactivity in female ovariectomized hypertensive rats are n
Braz J Med Biol Res. Publicado em: 16/01/2017
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4. Mechanisms of the antihypertensive effects of Nigella sativa oil in L-NAME-induced hypertensive rats
OBJECTIVES: This study was conducted to determine whether the blood pressure-lowering effect of Nigella sativa might be mediated by its effects on nitric oxide, angiotensin-converting enzyme, heme oxygenase and oxidative stress markers. METHODS: Twenty-four adult male Sprague-Dawley rats were divided equally into 4 groups. One group served as the control (
Clinics. Publicado em: 2015-11
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5. Mechanisms involved in the vasorelaxant effects produced by the acute application of amfepramone
in vitro to rat aortic ringsAmfepramone (diethylpropion) is an appetite-suppressant drug used for the treatment of overweight and obesity. It has been suggested that the systemic and central activity of amfepramone produces cardiovascular effects such as transient ischemic attacks and primary pulmonary hypertension. However, it is not known whether amfepramone produces immediate vas
Braz J Med Biol Res. Publicado em: 27/03/2015
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6. Combined aliskiren and L-arginine treatment has antihypertensive effects and prevents vascular endothelial dysfunction in a model of renovascular hypertension
Angiotensin II is a key player in the pathogenesis of renovascular hypertension, a condition associated with endothelial dysfunction. We investigated aliskiren (ALSK) and L-arginine treatment both alone and in combination on blood pressure (BP), and vascular reactivity in aortic rings. Hypertension was induced in 40 male Wistar rats by clipping the left rena
Braz J Med Biol Res. Publicado em: 24/10/2014
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7. Croton schiedeanus Schltd prevents experimental hypertension in rats induced by nitric oxide deficit
Croton schiedeanus Schltd (NV: "almizclillo") é utilizado na medicina tradicional da Colômbia para o tratamento da hipertensão arterial. Outras pesquisas demonstraram que a planta tem metabólitos como os flavonoides, os diterpenoides e os fenilbutanoides, os quais têm comprovados efeitos vasodilatadores vinculados com a via NO/GMPc. O objetivo deste est
Braz. J. Pharm. Sci.. Publicado em: 2013-12
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8. Desenvolvimento de Novos Metalofármacos Ativadores/Estimuladores da Enzima Guanilato Ciclase Solúvel / Development of Novel Activators metallodrugs / stimulators of soluble guanylate cyclase enzyme
Este trabalho é um esforço no sentido do desenvolvimento autóctone decomplexos coordenados com metais [Fe (II) e RU (II)] modelados a partir de grupos farmacofóricos que estimulam ou ativam a enzima guanilato ciclase solúvel(GCs). Para tanto, utilizou-se modelos in vitro de reatividades vascular (anéis de aorta) e medidas de pressão arterial in vivo p
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/09/2012
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9. Tension cost correlates with mechanical and biochemical parameters in different myocardial contractility conditions
OBJECTIVES: Tension cost, the ratio of myosin ATPase activity to tension, reflects the economy of tension development in the myocardium. To evaluate the mechanical advantage represented by the tension cost, we studied papillary muscle contractility and the activity of myosin ATPase in the left ventricles in normal and pathophysiological conditions. METHODS:
Clinics. Publicado em: 2012
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10. MANIPULAÇÃO DO EIXO ECA2/ANGIOTENSINA-(1-7)/RECEPTOR MAS NO TRATAMENTO DA DISFUNÇÃO ERÉTIL DE RATOS HIPERTENSOS E DIABÉTICOS / MANIPULAÇÃO DO EIXO ECA2/ANGIOTENSINA-(1-7)/RECEPTOR MAS NO TRATAMENTO DA DISFUNÇÃO ERÉTIL DE RATOS HIPERTENSOS E DIABÉTICOS
Estudos recentes têm estabelecido um novo eixo regulatório do Sistema Renina Angiotensina. Neste eixo, a Angiotensina-(1-7) [ANG-(1-7)] é produzida a partir da Angiotensina I (ANG I) e Angiotensina II (ANG II), através da atividade catalítica da isoforma 2 da enzima conversora de angiotensina (ECA2). Ao contrário do modelo clássico ECA / Angiotensina
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 12/08/2011
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11. Omeprazol atenua os efeitos anti-hipertensivos do nitrito de sódio em ratos / Omeprazole Attenuates the antihypertensive effect of sodium nitrite in rats
O óxido nítrico (NO) regula diversos sistemas orgânicos. Disfunções na produção ou disponibilidade de NO podem comprometer sua atuação fisiológica. Além da produção de NO pelas óxido nítrico sintetases, outras vias de produção de NO são relatadas, entre elas a conversão de nitrito a NO. O nitrito é o produto inicial da oxidação do NO, s
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 01/08/2011
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12. Efeito do Óxido Nítrico na Regulação de Parâmetros Cardiovasculares pela CVLM em Ratos com Hipertensão Renovascular 2R1C / Efeito do Óxido Nítrico na Regulação de Parâmetros Cardiovasculares pela CVLM em Ratos com Hipertensão Renovascular 2R1C
Hypertension may occur due to hyperactivity of neurons in the rostral ventrolateral medulla (RVLM) (Chan et al. 1991; Boone and McMillen, 1994, Suzuki et al. 1994; Minson et al., 1996) and/or due to a reduced tone of GABAergic neurons of the caudal ventrolateral medulla (CVLM) that projects to the RVLM. Furthermore, during hypertension occurs an elevation of
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/05/2010