Hypercholesterolemy
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1. Efeitos da hipercolesterolemia genetica e estatinas sobre a função mitocondrial / Effects of genetic hypercholesteromy and statins on mitochondrial functions
Recent results from our group demonstrated that hypercholesterolemic LDL receptor knockout (LDLR-/-) mice mitochondria possess a lower antioxidant capacity due to a large consumption of reducing equivalents from NADPH to sustain high rates of lipogenesis (Oliveira et al., FASEB J.; 19: 278-280; 2005). In this work, LDLR-/- mice oxidative stress was further c
Publicado em: 2007