Hyper J
Mostrando 1-12 de 47 artigos, teses e dissertações.
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1. Position-dependent correlation between TBX22 exon 5 methylation and palatal shelf fusion in the development of cleft palate
Abstract: DNA methylation is essential for spatiotemporally-regulated gene expression in embryonic development. TBX22 (Chr X: 107667964-107688978) functioning as a transcriptional repressor affects DNA binding, sumoylation, and transcriptional repression associated with X-linked cleft palate. This study aimed to explore the relationship and potential mechani
An. Acad. Bras. Ciênc.. Publicado em: 19/06/2019
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2. Vitamin D3 levels and NLRP3 expression in murine models of obese asthma: association with asthma outcomes
Vitamin D (25(OH)D3) is an essential nutrient that plays a role in the immune system. Serum 25(OH)D3 is found to be associated with asthma. However, the role of vitamin D in obese asthma remains unclear. Therefore, we investigated the association between vitamin D levels and asthma outcomes in a murine model of obese asthma. We also evaluated NLRP3 inflammas
Braz J Med Biol Res. Publicado em: 13/11/2017
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3. Tangeretin has anti-asthmatic effects via regulating PI3K and Notch signaling and modulating Th1/Th2/Th17 cytokine balance in neonatal asthmatic mice
Asthma is a chronic allergic disease characterized by airway inflammation, airway hyper-responsiveness (AHR), and mucus hypersecretion. T-lymphocytes are involved in the pathogenesis of asthma, mediating airway inflammatory reactions by secreting cytokines. The phosphoinositide 3-kinase (PI3K) and Notch signaling pathways are associated with T cell signaling
Braz J Med Biol Res. Publicado em: 20/07/2017
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4. The effect of thyroid hormones on the white adipose tissue gene expression of PAI-1 and its serum concentration
Metabolic syndrome is associated with an increased risk of developing cardiovascular diseases and Plasminogen activator inhibitor 1 (PAI-1) overexpression may play a significant role in this process. A positive correlation between adipose tissue gene expression of PAI-1 and its serum concentration has been reported. Furthermore, high serum levels of thyroid
Brazilian Journal of Medical and Biological Research. Publicado em: 2009-12
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5. Does hepatocellular carcinoma in non-alcoholic steatohepatitis exist in cirrhotic and non-cirrhotic patients?
Non-alcoholic steatohepatitis (NASH) has been associated with hepatocellular carcinoma (HCC) often arising in histologically advanced disease when steatohepatitis is not active (cryptogenic cirrhosis). Our objective was to characterize patients with HCC and active, histologically defined steatohepatitis. Among 394 patients with HCC detected by ultrasound ima
Brazilian Journal of Medical and Biological Research. Publicado em: 04/09/2009
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6. Health in early adulthood: the contribution of the 1978/79 Ribeirão Preto birth cohort
The increase in non-communicable chronic diseases of adults is due to demographic changes and changes in the risk factors related to physical activity, smoking habits and nutrition. We describe the methodology for the evaluation of persons at 23/25 years of age of a cohort of individuals born in Ribeirão Preto in 1978/79. We present their socioeconomic char
Brazilian Journal of Medical and Biological Research. Publicado em: 2006-08
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7. Desenvolvimento de software orientado a temas: um estudo de caso / Theme-oriented software development: a case study
O Paradigma Orientado a Objetos tem sido atualmente a abordagem dominante de desenvolvimento de software. Contudo, ela sofre da Tirania da Decomposição Dominante, pois não permite uma modularização adequada da implementação relativa a interesses estruturais. Como consequência, a implementação relativa a cada interesse estrutural fica espalhada pelo
Publicado em: 2006
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8. Abnormal expression of CD54 in mixed reactions of mononuclear cells from hyper-IgE syndrome patients
Hyper-IgE syndrome (HIES) is a rare multisystem disorder characterized by increased susceptibility to infections associated with heterogeneous immunologic and non-immunologic abnormalities. Most patients consistently exhibit defective antigen-induced-T cell activation, that could be partly due to altered costimulation involving accessory molecules; however,
Memórias do Instituto Oswaldo Cruz. Publicado em: 2004-03
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9. Current distribution in fused electrical networks
Electrical networks provide a natural model to study transport processes such us dielectric breakdown and metal insulator transition in disordered inhomogeneous conductors. We present a calculation for current distribution on an infinite hyper-cubic network due to an external applied current. This is used to compute, analytically, the redistribution of curre
Brazilian Journal of Physics. Publicado em: 2003-06
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10. Hyper-reactivity of Rabbits Sensitized with Bartonella bacilliformis
Mitchell, Paul D. (West Virginia University Medical Center, Morgantown), and John M. Slack. Hyper-reactivity of rabbits sensitized with Bartonella bacilliformis. J. Bacteriol. 92:769–779. 1966.—Sensitization with viable cells of Bartonella bacilliformis increased the susceptibility of rabbits to the lethality of subsequently administered Bartonella metab
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11. Specific cleavage of hyper-edited dsRNAs
Extended double-stranded DNA (dsRNA) duplexes can be hyper-edited by adenosine deaminases that act on RNA (ADARs). Long uninterrupted dsRNA is relatively uncommon in cells, and is frequently associated with infection by DNA or RNA viruses. Moreover, extensive adenosine to inosine editing has been reported for various viruses. A number of cellular antiviral d
Oxford University Press.
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12. Electrophoretic and Immunoelectrophoretic Studies of Sera from Normal, Tuberculous, and Noninfected Tuberculin-Sensitive Guinea Pigs1
Dardas, T. J. (Michigan State University, East Lansing), and V. H. Mallmann. Electrophoretic and immunoelectrophoretic studies of sera from normal, tuberculous, and noninfected tuberculin-sensitive guinea pigs. J. Bacteriol. 92:76–81. 1966.—Normal guinea pig serum was separated into seven fractions by electrophoresis on cellulose acetate membranes. Thirt