Huvec
Mostrando 1-12 de 150 artigos, teses e dissertações.
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1. Electrochemical Preparation and Evaluation of Cytotoxic Activity of Methoxyl-oxo-biseugenol, a New Oxidized Derivative of Biseugenol
Electrochemical procedures have emerged as a powerful tool for the synthesis of complex organic molecules including transformation of natural products. In this study, the electrosynthesis of biseugenol in MeOH afforded one new oxidized derivative, which was characterized as methoxyl-oxo-biseugenol (MOB) by nuclear magnetic resonance (NMR) and electrospray io
J. Braz. Chem. Soc.. Publicado em: 2021-05
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2. Effect of a novel bioceramic root canal sealer on the angiogenesis-enhancing potential of assorted human odontogenic stem cells compared with principal tricalcium silicate-based cements
Abstract Objective: This study evaluated the angiogenesis-enhancing potential of a tricalcium silicate-based mineral trioxide aggregate (ProRoot MTA), Biodentine, and a novel bioceramic root canal sealer (Well-Root ST) in human dental pulp stem cells (hDPSCs), human periodontal ligament stem cells (hPLSCs), and human tooth germ stem cells (hTGSCs). Methodo
J. Appl. Oral Sci.. Publicado em: 10/01/2020
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3. BjussuLAAO-II induces cytotoxicity and alters DNA methylation of cell-cycle genes in monocultured/co-cultured HepG2 cells
Abstract Background: The use of animal venoms and their toxins as material sources for biotechnological applications has received much attention from the pharmaceutical industry. L-amino acid oxidases from snake venoms (SV-LAAOs) have demonstrated innumerous biological effects and pharmacological potential against different cancer types. Hepatocellular carc
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 11/03/2019
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4. Reactive oxygen species generation mediated by NADPH oxidase and PI3K/Akt pathways contribute to invasion of Streptococcus agalactiae in human endothelial cells
BACKGROUND Streptococcus agalactiae can causes sepsis, pneumonia, and meningitis in neonates, the elderly, and immunocompromised patients. Although the virulence properties of S. agalactiae have been partially elucidated, the molecular mechanisms related to reactive oxygen species (ROS) generation in infected human endothelial cells need further investigati
Mem. Inst. Oswaldo Cruz. Publicado em: 05/04/2018
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5. Effect of a rosmarinic acid supplemented hemodialysis fluid on inflammation of human vascular endothelial cells
Chronic systemic inflammation and repetitive damage of vascular endothelia by incompatible dialysis system are probable causes of cardiovascular disease in patients on dialysis. The present study aimed to assess in vitro biocompatibility and anti-inflammatory effect of hemodialysis fluid supplemented with rosmarinic acid (RA) using human umbilical vein endot
Braz J Med Biol Res. Publicado em: 19/10/2017
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6. Cytotoxic factor secreted by Escherichia coli associated with sepsis facilitates transcytosis through human umbilical vein endothelial cell monolayers
Abstract Culture supernatant of sepsis-associated Escherichia coli (SEPEC) isolated from patients with sepsis caused loss of intercellular junctions and elongation of human umbilical vein endothelial cells (HUVEC). The cytotoxic factor was purified from culture supernatant of SEPEC 15 (serogroup O153) by liquid chromatography process. PAGE (polyacrylamide ge
Braz J Infect Dis. Publicado em: 2016-06
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7. Curli fimbria: an Escherichia coli adhesin associated with human cystitis
Abstract Escherichia coli is the major causative agent of human cystitis. In this study, a preliminary molecular analysis carried out by PCR (polymerase chain reaction) demonstrated that 100% of 31 E. coli strains isolated from patients with recurrent UTIs (urinary tract infections) showed the presence of the curli fimbria gene (csgA). Curli fimbria is known
Braz. J. Microbiol.. Publicado em: 2016-06
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8. Recombinant hepatitis C virus-envelope protein 2 interactions with low-density lipoprotein/CD81 receptors
Hepatitis C virus (HCV) envelope protein 2 (E2) is involved in viral binding to host cells. The aim of this work was to produce recombinant E2B and E2Y HCV proteins in Escherichia coli and Pichia pastoris, respectively, and to study their interactions with low-density lipoprotein receptor (LDLr) and CD81 in human umbilical vein endothelial cells (HUVEC) and
Mem. Inst. Oswaldo Cruz. Publicado em: 26/05/2015
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9. Papel dos microRNAs 221/222 na Liberação de Óxido Nítrico Induzida por Estatinas em Células Endoteliais Humanas
Fundamento: O óxido nítrico (NO) tem sido amplamente associado com proteção cardiovascular através de melhoria da função endotelial. Recentemente, novas evidências sobre a modulação do NO na liberação de microRNAs (miRs) têm sido relatadas, o que poderia estar envolvido com efeitos pleiotrópicos dependentes de estatinas, incluindo propriedades
Arq. Bras. Cardiol.. Publicado em: 16/12/2014
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10. Soro urêmico inibe a expressão in vitro da quimiocina SDF-1: possível impacto da toxicidade urêmica na lesão endotelial
Introdução: A disfunção endotelial é importante na patogênese da doença cardiovascular (DCV) relacionada à doença renal crônica (DRC). Stromal cell-derived factor-1 (SDF-1) é uma quimiocina que mobiliza células endoteliais progenitoras (EPC) e em conjunto com a interleucina-8 (IL-8) podem ser usadas como marcadores de reparo e lesão tecidual.
J. Bras. Nefrol.. Publicado em: 2014-06
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11. Estudo do papel biológico da enzima ácido graxo sintase (FASN) em células endoteliais derivadas dos vasos sanguíneos / Study of the biological role of the enzyme fatty acid synthase (FASN) in endothelial cells derived from blood vessels
Fatty acid synthase (FASN) is the anabolic enzyme with high expression and activity in several human malignancies, which is responsible for the endogenous synthesis of saturated fatty acids and consequently of the phospholipids present in cell membranes. Inhibition of FASN with orlistat (Xenical), an anti-obesity drug, is described as having anti-neoplastic
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/12/2011
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12. AvaliaÃÃo do potencial antitumoral e antiangiogÃnico de novos anÃlogos ftalimÃdicos da talidomida / EVALUATION OF THE ANTITUMOR AND ANTIANGIOGENIC POTENTIAL OF NEW FTHALIMIDES THALIDOMIDE ANALOGUES
The thalidomide was previously used to relieve gastric discomforts during pregnancy, and currently it is used for cancer treatment and inflammatory illnesses. Various phthalimides analogues of thalidomide have been researched for its antiangiogenic and immunemodulatory activity. In previous studies, these analogues showed absence of immunesuppressor activity
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 09/12/2011