Human Umbilical Cord
Mostrando 1-12 de 125 artigos, teses e dissertações.
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1. Haploidentical transplantation outcomes are comparable with those obtained with identical human leukocyte antigen allogeneic transplantation in Chilean patients with benign and malignant hemopathies
Abstract Introduction Patients with benign or malignant blood disorders, who require allogeneic stem cell transplantation and lack an identical human leukocyte antigen HLA identicalHL sibling donor, could be transplanted with hematopoietic stem cells from unrelated adult or umbilical cord donors. However, in our country, both approaches are costly and time-
Hematol., Transfus. Cell Ther.. Publicado em: 2020-03
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2. Spontaneous splenic rupture associated with multiple myeloma: a serious and unusual case
Abstract Introduction Patients with benign or malignant blood disorders, who require allogeneic stem cell transplantation and lack an identical human leukocyte antigen HLA identicalHL sibling donor, could be transplanted with hematopoietic stem cells from unrelated adult or umbilical cord donors. However, in our country, both approaches are costly and time-
Hematol., Transfus. Cell Ther.. Publicado em: 2020-03
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3. Effects of Human Umbilical Cord Mesenchymal Stem Cells on Renal Ischaemia-reperfusion Injury in Rats
Objective This study aims to observe the function of umbilical cord-mesenchymal stem cells (UC-MSCs) labelled with enhanced green fluorescent protein (eGFP) in the repair of renal ischaemia-reperfusion (I/R) injury, to determine the effects on inflammatory cascade in an established rat model and to explore possible pathogenesis. Materials and Methods Si
Int. braz j urol.. Publicado em: 2014-08
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4. Delivery of the Sox9 gene promotes chondrogenic differentiation of human umbilical cord blood-derived mesenchymal stem cells in an in vitro model
SRY-related high-mobility-group box 9 (Sox9) gene is a cartilage-specific transcription factor that plays essential roles in chondrocyte differentiation and cartilage formation. The aim of this study was to investigate the feasibility of genetic delivery of Sox9 to enhance chondrogenic differentiation of human umbilical cord blood-derived mesenchymal stem ce
Braz J Med Biol Res. Publicado em: 18/03/2014
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5. Níveis da quimiocina RANTES na placenta, plasma materno e plasma do cordão umbilical em gestantes normais e com síndrome de pré-eclâmpsia
Objective: To estimate RANTES levels at maternal plasma, umbilical cord blood plasma and placenta in preeclampsia syndrome and normal pregnancy. Methods: A cross-sectional study was conducted to estimate RANTES levels in maternal plasma, placenta and cord blood plasma in preeclampsia syndrome (n=33) compared to a control group of women with normal pregnancy
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/08/2012
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6. Avaliação da indiferenciação celular e indução de neurodiferenciação em co-cultivo de fibroblastos NIH 3T3 com células mononucleares do sangue de cordão umbilical
Cellular therapy represent a new frontier for the treatment of several diseases, including diseases related to central nervous system. Human umbilical cord blood is an attractive source of stem cells; however, it has a heterogeneous population with a small amount of mesenchymal stem cells. Currently, cell reprogramming induced by different methodologies can
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/01/2012
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7. Transplantation of mononuclear cells from human umbilical cord blood promotes functional recovery after traumatic spinal cord injury in Wistar rats
Cell transplantation is a promising experimental treatment for spinal cord injury. The aim of the present study was to evaluate the efficacy of mononuclear cells from human umbilical cord blood in promoting functional recovery when transplanted after a contusion spinal cord injury. Female Wistar rats (12 weeks old) were submitted to spinal injury with a MASC
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-01
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8. O uso de células-tronco adultas humanas na recuperação funcional da lesão medular trumática em ratas Wistar
Spinal cord injury is a debilitating disease and yet no effective treatment is available. In this framework cell therapy represents a new strategy to treat this condition. Adult stem cells are potential sources for cell transplantation in order to minimize injury and promote the recovery of damaged tissues, such as the spinal cord. The purpose of this Thesis
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2011
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9. Impacto da exposição fetal ao HIV-1 na função das células T e das células dendríticas de neonatos não infectados / Impact of HIV-1 fetal exposition in Tcells and dendritic cells function from non infected neonates
The acquired immunodeficiency syndrome (AIDS), caused by human immunodeficiency virus (HIV), is one of the most impelling epidemic in the world, and the HIV-infection in young women has been increasing fast in the recent times, mainly in developing countries where most of them become pregnant precociously. Although the great majority of the pediatric AIDS ca
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/08/2010
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10. Human umbilical cord blood cells in infarcted rats
Therapy with bone marrow-derived cells has been used in ischemic patients with reported success. The aim of this study was to determine the therapeutic efficacy of fresh and frozen human umbilical cord blood cells (hUCB) in Wistar rats submitted to permanent occlusion of the left coronary artery. Three hours after myocardial infarction, 2 x 10(7) hUCB cells
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-03
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11. Comparing two human umbilical cord mesenchymal stem cell isolation protocols
Human umbilical cord is a rich source of mesenchymal stem cells (MSCs) as reported in many studies. Many techniques are used to obtain these cells and their variations are related to the part of the tissue from which the stem cells can be extracted (umbilical vein, arteries, Wharton’s jelly or the whole umbilical cord - UC). In this sense, it is really imp
Publicado em: 2010
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12. Comparative quantification of umbilical cord blood CD34+ and CD34+ bright cells using the procount tm-bd and ishage protocols
The total number of CD34+ cells is the most relevant clinical parameter when selecting human umbilical cord blood (HUCB) for transplantation. The objective of the present study was to compare the two most commonly used CD34+ cell quantification methods (ISHAGE protocol and ProCount™ - BD) and analyze the CD34+ bright cells whose 7-amino actinomycin D (7AAD
Publicado em: 2010