Human Respiratory Epithelial Cells
Mostrando 1-12 de 201 artigos, teses e dissertações.
-
1. Regulation of HPV transcription
Human papillomavirus infection is associated with the development of malignant and benign neoplasms. Approximately 40 viral types can infect the anogenital mucosa and are categorized into high- and low-risk oncogenic human papillomavirus, depending on their association with the development of cervical carcinoma. High-risk human papillomavirus 16 and 18 are d
Clinics. Publicado em: 11/10/2018
-
2. Modelo de regulação dos nucleotídeos extracelulares no líquido superficial das vias respiratórias
Extracellular nucleotides play a key role in the regulation of mucociliary clearance and thus are essential in protecting the airways against inhaled pathogens. Adenosine triphosphate (ATP), adenosine diphosphate (ADP) and adenosine monophosphate (AMP) nucleotides are secreted by the respiratory epithelium to the airway surface liquid, where they are metabol
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 09/03/2012
-
3. Influência de pré-tratamentos de células epiteliais com penicilina e eritromicina na aderência e na viabilidade intracelular de Corynebacterium diphtheriae / Influence of epithelial cells pre-treatment with penicilin and erythromycin in adherence and intracellular viability of Corynebacterium diphtheriae
Diphtheria is a syndrome caused by Toxigenic Corynebacterium diphtheriae. Although immunization programs have kept diphtheria under control in the great majority of developed countries, the disease remains endemic in many parts of the world, especially in individuals partially immunized to diphtheria toxoid. Additionally, an increase in the number of cases o
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/01/2012
-
4. Aggregative adherent strains of Corynebacterium pseudodiphtheriticum enter and survive within HEp-2 epithelial cells
Corynebacterium pseudodiphtheriticum is a well-known human pathogen that mainly causes respiratory disease and is associated with high mortality in compromised hosts. Little is known about the virulence factors and pathogenesis of C. pseudodiphtheriticum. In this study, cultured human epithelial (HEp-2) cells were used to analyse the adherence pattern, inter
Memórias do Instituto Oswaldo Cruz. Publicado em: 2012-06
-
5. Efeito de ExoU na ativação de NF-κB e na secreção de IL-8 por células humanas infectadas por Pseudomonas aeruginosa / Effect of Exou on the activation of the NF-κB and the secretion of the IL-8 in human cells infected with Pseudomonas
ExoU, a cytotoxin produced by the opportunistic pathogen Pseudomonas aeruginosa that is translocated into host cell cytosol by the type three secretory system, has been associated with severity of acute infections. We have previously described the potent ExoU proinflammatory activity, which accounts for a market recruitment of neutrophils to infected tissues
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/07/2011
-
6. Adeno-associated virus for cystic fibrosis gene therapy
Gene therapy is an alternative treatment for genetic lung disease, especially monogenic disorders such as cystic fibrosis. Cystic fibrosis is a severe autosomal recessive disease affecting one in 2500 live births in the white population, caused by mutation of the cystic fibrosis transmembrane conductance regulator (CFTR). The disease is classically character
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-11
-
7. Atividade pró-coagulante da toxina ExoU de Pseudomonas aeruginosa: efeito sobre a expressão do fator tissular em células epiteliais respiratórias / Procoagulant activity of Pseudomonas aeruginosa toxin ExoU: effect on the expression of tissue factor by airway epithelial cells
To evaluate the capacity of the P. aeruginosa toxin ExoU to induce the expression of tissue factor (TF) by epithelial respiratory cells from the BEAS-2B cell line, cells infected with the ExoU-producing PA103 bacterial strain were compared with cells infected with a mutant obtained by deletion of the exoU gene and with control non-infected cells in their i)
Publicado em: 2008
-
8. Mecanismos de patogenia do Mycobacterium leprae: Análise de proteínas extracelulares e efeitos sobre o metabolismo lipídico do hospedeiro. / Mechanisms of Mycobacterium leprae pathogenesis: Analysis of the extracellular proteins and effect on the host lipid metabolism.
The complete sequence of the Mycobacterium leprae genome, together with recent advances in the definition of its proteome, are contributing to our understanding of leprosy pathogenesis, so far a difficult task due to the unique properties of this bacterium. The major goal of the present study was to identify and functionally characterize extracellular M. lep
Publicado em: 2008
-
9. Neutrophil transepithelial migration: role of toll-like receptors in mucosal inflammation
The symptomatic phases of many inflammatory diseases are characterized by migration of large numbers of neutrophils (PMN) across a polarized epithelium and accumulation within a lumen. For example, acute PMN influx is common in diseases of the gastrointestinal system (ulcerative colitis, Crohn's disease, bacterial enterocolitis, gastritis), hepatobiliary sys
Memórias do Instituto Oswaldo Cruz. Publicado em: 2005-03
-
10. Respiratory epithelial cell expression of human transforming growth factor-alpha induces lung fibrosis in transgenic mice.
Increased production of EGF or TGF-alpha by the respiratory epithelial cells has been associated with the pathogenesis of various forms of lung injury. Growth factors and cytokines are thought to act locally, via paracrine and autocrine mechanisms, to stimulate cell proliferation and matrix deposition by interstitial lung cells resulting in pulmonary fibrosi
-
11. Induction of Proinflammatory Cytokines from Human Respiratory Epithelial Cells after Stimulation by Nontypeable Haemophilus influenzae
Nontypeable Haemophilus influenzae (NTHi) causes repeated respiratory infections in patients with chronic lung diseases. These infections are characterized by a brisk inflammatory response which results in the accumulation of polymorphonucleated cells in the lungs and is dependent on the expression and secretion of proinflammatory cytokines. We hypothesize t
American Society for Microbiology.
-
12. Gene transfer into respiratory epithelial cells by targeting the polymeric immunoglobulin receptor.
A system for targeting foreign DNA to epithelial cells in vitro has been developed by exploiting receptor-mediated endocytosis. The polymeric immunoglobulin receptor transports dimeric immunoglobulin A and immunoglobulin M through epithelial cells, including those of the respiratory tract, by binding the immunoglobulins at the basolateral surface and transpo