Human Igfbp7 Gene
Mostrando 1-6 de 6 artigos, teses e dissertações.
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1. Análise da expressão gênica em células-tronco mesenquimais de medula óssea humana durante o comprometimento com a linhagem osteogênica / Gene expression analysis of mesenchymal stem cells from human bone marrow during the osteogenic commitment
As células-tronco são definidas como células capazes de auto-renovação e diferenciação em células especializadas. Dentre as células-tronco adultas, as mesenquimais ocupam uma posição de destaque. São células multipotentes que podem originar células de origem mesodérmica, como osteoblastos, adipócitos e condrócitos. Além disso, vários estud
Publicado em: 2009
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2. Bone marrow stroma modulates the expression of several drug resistance/sensitivity genes in pediatric acute limphoblastic leukemia / O estroma da medula ossea e a sua influencia na expressão de genes de resistencia e sensibilidade a quimioterapicos na leucemia linfoide aguda (LLA) pediatrica
The intrinsic or acquired chemotherapy resistance composites one of the most important causes of failures in the treatment of pediatric ALL. The ALL and bone marrow microenvironment nteraction contributes for the proliferation and resistance to the chemotherapy regimen of leukemic cells probably through a great variety of cellular mechanisms, including incre
Publicado em: 2007
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3. Human Papillomavirus Type 16 E7 Oncoprotein Binds and Inactivates Growth-Inhibitory Insulin-Like Growth Factor Binding Protein 3
The E7 protein encoded by human papillomavirus type 16 is one of the few viral genes that can immortalize primary human cells and thereby override cellular senescence. While it is generally assumed that this property of E7 depends on its interaction with regulators of the cell cycle, we show here that E7 targets insulin-like growth factor binding protein 3 (
American Society for Microbiology.
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4. Identification of a family of low-affinity insulin-like growth factor binding proteins (IGFBPs): Characterization of connective tissue growth factor as a member of the IGFBP superfamily
The insulin-like growth factor (IGF) binding proteins (IGFBPs) modulate the actions of the insulin-like growth factors in endocrine, paracrine, and autocrine settings. Additionally, some IGFBPs appear to exhibit biological effects that are IGF independent. The six high-affinity IGFBPs that have been characterized to date exhibit 40–60% amino acid sequence
The National Academy of Sciences of the USA.
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5. Liver-specific expression of human insulin-like growth factor binding protein 1: functional role of transcription factor HNF1 in vivo.
Tissue-specific expression of insulin-like growth factor binding protein 1 (IGFBP-1) in the liver has been studied using differentiated (H4II and C2Rev7) and dedifferentiated (H5 and C2) rat hepatoma cell lines. Northern blot analysis showed that endogenous IGFBP-1 mRNA was expressed only in the differentiated cell lines. The first 341 base pairs 5' to the t
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6. Diverse gene sequences are overexpressed in werner syndrome fibroblasts undergoing premature replicative senescence.
Genes that play a role in the senescent arrest of cellular replication are likely to be overexpressed in human diploid fibroblasts (HDF) derived from subjects with Werner syndrome (WS) because these cells have a severely curtailed replicative life span. To identify some of these genes, a cDNA library was constructed from WS HDF after they had been serum depl