Human Genetics
Mostrando 1-12 de 488 artigos, teses e dissertações.
-
1. Dysregulation in erythrocyte dynamics caused by SARS-CoV-2 infection: possible role in shuffling the homeostatic puzzle during COVID-19
Abstract Introduction The evolving COVID-19 pandemic became a hallmark in human history, not only by changing lifestyles, but also by enriching scientific knowledge on viral infection and its consequences. Objective Although the management of cardiorespiratory changes is pivotal to a favorable prognosis during severe clinical findings, dysregulation of oth
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
-
2. Genetics of COVID-19
Abstract Objective This narrative, non-systematic review provides an update on the genetic aspects of the SARS-CoV-2 virus and its interactions with the human genome within the context of COVID-19. Although the main focus is on the etiology of this new disease, the genetics of SARS-CoV-2 impacts prevention, diagnosis, prognosis, and the development of thera
J. Pediatr. (Rio J.). Publicado em: 2021-08
-
3. What can we learn from measuring IgE to allergens and allergen components in tropical and subtropical settings in Brazil?
Abstract Objective This narrative, non-systematic review provides an update on the genetic aspects of the SARS-CoV-2 virus and its interactions with the human genome within the context of COVID-19. Although the main focus is on the etiology of this new disease, the genetics of SARS-CoV-2 impacts prevention, diagnosis, prognosis, and the development of thera
J. Pediatr. (Rio J.). Publicado em: 2021-08
-
4. Mapeamento genético laboral: prospecção axiológica, bioética e legislação brasileira
Resumo Objetiva-se comparar o estado da legislação brasileira sobre mapeamento genético com o de legislações internacionais visando dimensionar a realidade normativa do país quanto às tendências sociais de reconhecimento das diferenças e a abertura jurídica prospectiva, com foco na área laboral. Trata-se de revisão de literatura e pesquisa docume
Rev. Bioét.. Publicado em: 10/01/2020
-
5. HLA-B*14 allele predicts HIV-1 mother-to-child-transmission, in Salvador, Brazil
ABSTRACT Background: Class I human leukocyte antigens, especially the molecules encoded at the B locus (HLA-B), are associated with AIDS progression risk. Different groups of HLA-B alleles have been associated to a protective effect or increasing susceptibility to HIV infection and are expressed from the earliest stages of gestation. Objective: The aim of
Braz J Infect Dis. Publicado em: 18/07/2019
-
6. From abortion-inducing medications to Zika Virus Syndrome: 27 years experience of the First Teratogen Information Service in Latin America
Abstract In 1990, the first Teratogen Information Service in Brazil (SIAT) was implemented in the Medical Genetics Service at Hospital de Clinicas de Porto Alegre. SIAT is a free-to-use information service both to health professionals and the general population, especially to women who are pregnant or planning pregnancy. The main objective of this paper is t
Genet. Mol. Biol.. Publicado em: 11/04/2019
-
7. Periferia pensada em termos de falta: uma análise do campo da genética humana e médica
Resumo Este artigo busca discutir dimensões da relação entre centros e periferias na produção e circulação do conhecimento, a partir de um estudo de caso que se debruça sobre a área da genética humana e médica no Brasil. Para tanto, realizou-se um trabalho de campo que compreendeu a seleção de uma amostra de pesquisadores da área no Brasil, que
Sociologias. Publicado em: 2019-04
-
8. Karyotyping and population genetics in Cold War Mexico: Armendares’s and Lisker’s characterization of child and indigenous populations, 1960s-1980s
Resumo Aborda o trabalho dos geneticistas Salvador Armendares e Rubén Lisker, entre 1960 e 1980, para analisar como se insere nos estudos biológicos humanos do pós-1945, e demonstra como as populações estudadas por eles, a infantil e a indígena, podem ser consideradas laboratórios de produção de conhecimento. O artigo revela como as populações for
Hist. cienc. saude-Manguinhos. Publicado em: 2019-03
-
9. Biomedical knowledge in Mexico during the Cold War and its impact in pictorial representations of Homo sapiens and racial hierarchies
Resumo Este artigo traça um panorama do estado da genética e do conhecimento biomédico no México durante a segunda metade do século XX, assim como seu impacto na representação visual de grupos humanos e hierarquias raciais, baseado em estudos sociais da imagem e visualização cientifica e de seus métodos e conceitos teóricos. Também aborda a genea
Hist. cienc. saude-Manguinhos. Publicado em: 2019-03
-
10. Mathematical modelling of vector-borne diseases and insecticide resistance evolution
Abstract Background: Vector-borne diseases are important public health issues and, consequently, in silico models that simulate them can be useful. The susceptible-infected-recovered (SIR) model simulates the population dynamics of an epidemic and can be easily adapted to vector-borne diseases, whereas the Hardy-Weinberg model simulates allele frequencies a
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 08/02/2018
-
11. Management framework paradigms for disorders of sex development
Until 2005, questions regarding medical treatment and diagnostic information on Disorders of Sex Development (DSD) were not systematically discussed with both the patients and their families; however, the way these patients are currently treated have been changing with time. Interventional changes in the clinical-psychotherapeutic-surgical areas of DSD deter
Arch. Endocrinol. Metab.. Publicado em: 28/08/2015
-
12. Lymphocyte subsets in human immunodeficiency virus-unexposed Brazilian individuals from birth to adulthood
Ethnic origin, genetics, gender and environmental factors have been shown to influence some immunologic indices, so that development of reference values for populations of different backgrounds may be necessary. We have determined the distribution of lymphocyte subsets in healthy Brazilian individuals from birth to adulthood. Lymphocyte subsets were determin
Mem. Inst. Oswaldo Cruz. Publicado em: 21/11/2014