Hts
Mostrando 1-12 de 65 artigos, teses e dissertações.
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1. The reliability and validity of decreased sound tolerance scale-screening
Abstract Objectives: Decreased Sound Tolerance (DST) is a negative reaction to a sound that does not cause any reaction in an individual with normal hearing. DST’s subclasses include hyperacusis, phonophobia, and misophonia, which are distinct and have therapy variations. There is no diagnostic method or scale that distinguishes them in the literature. Th
Brazilian Journal of Otorhinolaryngology. Publicado em: 2022
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2. Short Circuit and Recovery Time Tests in a helical bifilar R-SFCL module
Abstract Superconducting Fault Current Limiter (SFCL) modules with distinct arrangements have been investigated, seeking design and performance enhancements. In this context, this work aims to propose a design for resistive SFCL (R-SFCL) modules, using RE-Ba-Cu-O high-temperature superconducting tapes (HTS) wound on an alternative support material. An R-SFCL
J. Microw. Optoelectron. Electromagn. Appl.. Publicado em: 2021-06
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3. Determination of the grapevine virome by high-throughput sequencing and grapevine viruses detection in Serra Gaúcha, Brazil
ABSTRACT Among grapevine (Vitis spp.) pathogens, viruses stand out, considering that this fruit plant is broadly susceptible to them and that they cause several diseases, reducing quality and yield of grape production. However, detecting and identifying viral infections in grapevines can be challenging. The objectives of this study were to detect grapevine v
Rev. Ceres. Publicado em: 2020-04
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4. Human virome in nasopharynx and tracheal secretion samples
BACKGROUND In Brazil the implementation of the Sentinel Surveillance System of Influenza began in 2000. Central public health laboratories use reverse transcription-quantitative polymerase chain reaction (RT-qPCR) for diagnosis of respiratory viruses, but this protocol identifies only specific targets, resulted in inconclusive diagnosis for many samples. T
Mem. Inst. Oswaldo Cruz. Publicado em: 03/10/2019
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5. Brazilian malaria molecular targets (BraMMT): selected receptors for virtual high-throughput screening experiments
BACKGROUND Owing to increased spending on pharmaceuticals since 2010, discussions about rising costs for the development of new medical technologies have been focused on the pharmaceutical industry. Computational techniques have been developed to reduce costs associated with new drug development. Among these techniques, virtual high-throughput screening (v
Mem. Inst. Oswaldo Cruz. Publicado em: 25/02/2019
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6. Busca virtual de compostos bioativos: conceitos e aplicações
The search and use of bioactive compounds for different applications have been investigated, since ancient time. Virtual screening (VS) has emerged as alternative methodological approach to the Combinatory Chemistry and High-Throughput Screening (HTS) in identifying novel drug candidates. In VS, only compounds that are selected applying different computation
Quím. Nova. Publicado em: 2018-06
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7. 2,3,8-Trisubstituted Quinolines with Antimalarial Activity
ABSTRACT Combination therapy drugs are considered a fundamental way to control malaria as it mimimizes the risk of emergence of resistance to the individual partner drugs. Consequently, this type of therapy constitutes a driving force for the discovery of new drugs with different modes of action, since this will provide options for combining different drugs
An. Acad. Bras. Ciênc.. Publicado em: 21/05/2018
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8. Heat Transfer Search Algorithm for Sizing Optimization of Truss Structures
Abstract Heat transfer search (HTS) is a novel metaheuristic optimization algorithm that simulates the laws of thermodynamics and heat transfer. In this study, the HTS algorithm is adapted to truss structure optimization. Sizing optimization searches for the minimum weight of a structure subject to stress and displacement constraints. Three truss structures
Lat. Am. j. solids struct.. Publicado em: 2017-03
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9. Non-clinical studies required for new drug development - Part I: early in silico and in vitro studies, new target discovery and validation, proof of principles and robustness of animal studies
This review presents a historical overview of drug discovery and the non-clinical stages of the drug development process, from initial target identification and validation, through in silico assays and high throughput screening (HTS), identification of leader molecules and their optimization, the selection of a candidate substance for clinical development, a
Braz J Med Biol Res. Publicado em: 24/10/2016
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10. Endophytic fungi producing of esterases: evaluation in vitro of the enzymatic activity using pH indicator
A sensitive and efficient colorimetric method was optimized for detection of esterase enzymes produced by endophytic fungi for development of High-Throughput Screening (HTS). The fungi were isolated and obtained previously from plant species of Cerrado and Atlantic Forest located in areas of environmental preservation in the State of Sao Paulo / Brazil, as p
Braz. J. Microbiol.. Publicado em: 10/01/2014
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11. Reação de deslocamento gás-água em catalisadores de platina suportados em TiO2-CeO2
Neste trabalho foram preparados catalisadores de platina suportados em CeO2, TiO2 e TiO2- CeO2 para aplicação na reação de deslocamento gás-água também conhecida como shift ou WGSR Water Gas Shift Reaction. Os suportes mistos de óxidos de titânio modificados com óxido de cério e os catalisadores de platina suportados foram obtidos pelo método da
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/03/2012
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12. Perfil dos hormônios da tireoide em pacientes com câncer de mama em estado de menopausa
OBJETIVO: Verificar o perfil dos hormônios tireóideos (HTs) em pacientes pós-menopausa portadoras de carcinoma de mama (CaM). SUJEITOS E MÉTODOS: Participaram 12 pacientes com CaM em estádio I ou II sem intervenções que pudessem interferir na progressão tumoral e um grupo controle com 18 pacientes em pós-menopausa sem CaM. Foram dosados os níveis s
Arquivos Brasileiros de Endocrinologia & Metabologia. Publicado em: 2012-06