Hsp100 Heat Shock Proteins
Mostrando 1-12 de 32 artigos, teses e dissertações.
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1. FUNCTIONAL PROTEOMICS OF CIRRHOSIS AND HEPATOCELLULAR CARCINOMA / ProteÃmica Funcional da Cirrose e do Carcinoma Hepatocelular
Introduction. Cancer is the most common given name to a series of molecular and physiological events which result in genetic instability and biochemical imbalance in cells. Among the seven events that drives cell cancer, the role of chronic inflammation and tumor microenvironment in cancer development were highlighted in this work . To experimentally evaluat
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 26/03/2012
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2. Analise da expressão de chaperonas moleculares em plantas e clonagem, purificação e caracterização inicial das proteinas Hsp100 e Hsp90 de cana-de-açucar / Expression analysis of plant molecular chaperones and cloning, purification and primary charaterization of the proteins Hsp 100 and Hsp90 from sugarcane
Proteins are macromolecules that are vital to the functioning cell, participating in most of the biological reactions as well as structural components. To perform its function, a protein need to achieve its native structure through a process called protein folding. In this context, the molecular chaperone proteins are able to assist in the folding of other p
Publicado em: 2009
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3. Desenvolvimento de um método sorológico para o diagnóstico laboratorial da esquistossomose mansoni baseado em peptídeos sintéticos / Development of a serologic method for laboratory diagnosis of the schistosomiasis mansoni based on synthetic peptides
Based on algorithms of hidrophilicity and flexibility, obtained by the use of the ProtScale software, disposable at the site http://au.expasy.org/cgi-bin/protscale.pl, seven potentially antigenic peptides were selected from different Schistosoma mansoni proteins: cathepsin B (Sm31), heat shock protein (SmHSP-70), cathodic circulating antigen (CCA) and the po
Publicado em: 2005
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4. PRECONDITIONING OF ORGAN DONORS WITH LOW LEVELS OF CARBON MONOXIDE REDUCES GRAFT IMMUNOGENICITY AND IMPROVES LONGTERM ALLOGRAFT FUNCTION
Background: Chronic rejection remains the major obstacle for successful transplantation, and to date there is no effective treatment. Events occurring prior to organ transplantation such as brain death, harvesting procedure, and ischemia-reperfusion injury lead to unspecific inflammatory damages danger signals - that increase graft immunogenicity and reduce
Publicado em: 2005
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5. A novel role for 100 kD heat shock proteins in the parasite Leishmania donovani
Heat shock proteins of the 100 kD family have been known to confer general stress tolerance in yeast and plants. Several protozoan parasites possess genes for Hsp100 proteins. In Leishmania species the protein is expressed under heat stress and during the mammalian stage, the amastigote. We show here that replacement of the clpB gene which encodes Hsp 100 do
Cell Stress Society International.
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6. Two mammalian heat shock proteins, HSP90 and HSP100, are actin-binding proteins.
Two high molecular weight heat shock proteins, HSP90 (Mr, 90,000) and HSP100 (Mr, 100,000), were separately purified from extracts of cultured cells of a mouse lymphoma cell line, L5178Y. Both of the HSPs exist in homodimeric form under physiological conditions. Their physicochemical properties are quite similar to each other. Each of the purified HSPs was s
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7. Chlamydial heat shock proteins and trachoma.
Two chlamydial proteins (HSP-60 and HSP-70) have marked homology with bacterial and mammalian heat shock proteins. Previous studies have indicated that when inoculated into the eyes of immune animals, a Triton X-100 extract of chlamydia containing HSP-60 induces an ocular delayed-type hypersensitivity reaction. The potential for HSP-70 to induce a similar re
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8. Expression of 65- and 67-kilodalton heat-regulated proteins and a 70-kilodalton heat shock cognate protein of Leishmania donovani in macrophages.
Heat shock protein (HSP) expression was examined in murine bone marrow-derived macrophages infected with stationary-phase promastigotes of Leishmania donovani. Immunoblotting performed with a rabbit polyclonal antiserum raised against HSP60 from Heliothis virescens (moth) revealed the de novo appearance of 65- and 67-kDa proteins in leishmania-infected macro
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9. A Small Heat Shock Protein Cooperates with Heat Shock Protein 70 Systems to Reactivate a Heat-Denatured Protein1
Small heat shock proteins (sHsps) are a diverse group of heat-induced proteins that are conserved in prokaryotes and eukaryotes and are especially abundant in plants. Recent in vitro data indicate that sHsps act as molecular chaperones to prevent thermal aggregation of proteins by binding non-native intermediates, which can then be refolded in an ATP-depende
American Society of Plant Physiologists.
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10. Distribution, phosphorylation, and activities of Hsp25 in heat-stressed H9c2 myoblasts: a functional link to cytoprotection
The behavior of the endogenous heat shock protein 25 (Hsp25) in heat-stressed rat H9c2 myoblasts was studied. After mild or severe heating, this protein became less extractable with Triton X-100 and displayed characteristic immunofluorescence patterns, namely (1) granules in the nucleus, and (2) association with F-actin bundles in the cytoplasm. The intranuc
Cell Stress Society International.
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11. A Low Molecular Mass Heat-Shock Protein Is Localized to Higher Plant Mitochondria.
When pea (Pisum sativum L. var Douce Provence) plants are shifted from a normal growth temperature of 25[deg] C up to 40[deg] C for 3 h, a novel 22-kD protein is produced and accumulates in the matrix compartment of green leaf mitochondria. HSP22 was purified and used as antigen to prepare guinea pig antiserum. The expression of HSP22 was studied using immun
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12. Genetic Analysis Reveals Domain Interactions of Arabidopsis Hsp100/ClpB and Cooperation with the Small Heat Shock Protein Chaperone SystemW⃞
We have defined amino acids important for function of the Arabidopsis thaliana Hsp100/ClpB chaperone (AtHsp101) in acquired thermotolerance by isolating recessive, loss-of-function mutations and a novel semidominant, gain-of-function allele [hot1-4 (A499T)]. The hot1-4 allele is unusual in that it not only fails to develop thermotolerance to 45°C after accl
American Society of Plant Biologists.