Hsp 1
Mostrando 1-12 de 1023 artigos, teses e dissertações.
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1. Update on the pathogenesis of vitiligo
Abstract Vitiligo is a complex disease whose pathogenesis results from the interaction of genetic components, metabolic factors linked to cellular oxidative stress, melanocyte adhesion to the epithelium, and immunity (innate and adaptive), which culminate in aggression against melanocytes. In vitiligo, melanocytes are more sensitive to oxidative damage, lead
Anais Brasileiros de Dermatologia. Publicado em: 2022
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2. Vitamin C (Ascorbic acid) protects from neuropathy caused by cisplatin, through enhanced heat shock protein-70 and reduced oxidant effect
SUMMARY OBJECTIVE: We aimed to determine whether vitamin C has a protective effect on cisplatin-induced neuropathy in rats. METHODS: In total, 24 rats were included in the study of which 8 rats (no drug administered) were categorized as the control group. The remaining 16 rats were given a total dose of 20 mg/kg cisplatin to induce neuropathy. These drug-a
Revista da Associação Médica Brasileira. Publicado em: 2022
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3. Study on the mechanism and therapeutic effect of Antelope horn treatment on cerebral ischemia reperfusion injury of mouse
Abstract To the mechanism and therapeutic effect of Antelope horn treatment on cerebral ischemia reperfusion injuries under different levels of concentration. The process is as follows: (1) establish MCAO mouse model, test the modelling using traction and open field experiments, use TTC staining to detect the protective effect of Antelope horn treatment on c
Food Sci. Technol. Publicado em: 2021-06
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4. Heterose e diversidade genética nos cruzamentos das cultivares de gladíolo Amsterdam e White Prosperity
Resumo O gladíolo é um dos bulbos de flores de corte mais importantes e populares do Irã. O objetivo desta pesquisa foi produzir novos híbridos de alta qualidade por meio de hibridação. Duas combinações de híbridos promissores (OPRC16 e OPRC57) foram produzidas à partir das variedades “Amsterdam” e “White Prosperity”. A pesquisa foi realiza
Ornam. Hortic.. Publicado em: 2020-06
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5. Caracterização do gene do choque térmico (HSP-70.1) e sua relação com características de produção em bovinos leiteiros criados no semiárido brasileiro
RESUMO Objetivou-se com este trabalho avaliar a diversidade genética do gene HSP-70.1 e associar os polimorfismos encontrados com a performance de vacas leiteiras das raças Holandesa, Girolando (5/8H-G) e Sindi criadas em região do semiárido brasileiro. Os polimorfismos foram identificados e avaliados pela técnica de PCR-RFLP, usando-se a enzima de rest
Arq. Bras. Med. Vet. Zootec.. Publicado em: 2020-05
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6. Use of two new formulations as bovine embryo manipulation solution
Abstract This study aimed to evaluate the effect of two Embryo Manipulation Solutions (EMS and EMS supplemented) in maintenance of the viability of embryos, initially using structures derived from mice (first phase). Next, the efficiency of these solutions in routines of bovine embryo transfer was evaluated (second stage). Mice embryos were used in the stage
Anim. Reprod.. Publicado em: 25/11/2019
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7. The profile and clinical outcomes of patients with renal involvement due to IgA vasculitis: is azathioprine a good option for treatment?
Abstract Background: The Henoch-Schonlein Purpura (HSP) or IgA vasculitis is the most common vasculitis of childhood and may occur with renal involvement, with hematuria and / or proteinuria, and may cause severe and non-reversible sequelae. Objectives: To establish the profile of patients with renal involvement due to IgA vasculitisand to describe our exp
Adv. rheumatol.. Publicado em: 29/07/2019
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8. Detection of HIV-1 infections in blood donors during the pre-seroconversion window period in São Paulo, Brazil
Abstract By decreasing the pre-seroconversion window period, nucleic acid testing (NAT) has improved the safety of blood products and reduced the risk of transfusion-transmitted infections. Between 2011 and 2017, NAT determinations for approximately 898,202 donations were performed at Fundação Pró-Sangue/Hemocentro de São Paulo (FPS-HSP). Three seronegat
Rev. Soc. Bras. Med. Trop.. Publicado em: 16/05/2019
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9. The Expression of and Preoperative Correlation between Heat-Shock Protein 70, EuroSCORE, and Lactate in Patients undergoing CABG with Cardiopulmonary Bypass
Abstract Objetive: Coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB) improved symptoms and increased survival and quality of life in patients with coronary artery disease. However, it should be the main cause of a complex organic systemic inflammatory response that greatly contributes to several postoperative adverse effects. Methods
Braz. J. Cardiovasc. Surg.. Publicado em: 2019-04
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10. Hereditary spastic paraplegia: a clinical and epidemiological study of a Brazilian pediatric population
RESUMO Objetivo: Investigar paraplegia espástica hereditária (PEH) em uma amostra brasileira de pacientes pediátricos. Métodos: Foram colhidos dados clínicos, epidemiológicos, radiológicos e laboratoriais de 35 pacientes. Resultados: Doze pacientes foram classificados como PEH simples (PEH-S), e 23 como PEH complicada (PEH-C). A média de idade de
Arq. Neuro-Psiquiatr.. Publicado em: 2019-01
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11. α-Linolenic acid prevents hepatic steatosis and improves glucose tolerance in mice fed a high-fat diet
OBJECTIVES: Dietary omega-3 fatty acids have been efficacious in decreasing serum cholesterol levels and reducing the risk of cardiovascular disease. However, the metabolic and molecular changes induced by the omega-3 fatty acid α-linolenic acid (ALA), which is found in linseed oil, are not fully understood. In this study, we showed a correlation between A
Clinics. Publicado em: 29/10/2018
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12. Mechanisms involved in anti-aging effects of guarana (Paullinia cupana) in Caenorhabditis elegans
Guarana (Paullinia cupana) is habitually ingested by people in the Amazon region and is a key ingredient in various energy drinks consumed worldwide. Extension in longevity and low prevalence of chronic age-related diseases have been associated to habitual intake of guarana. Anti-aging potential of guarana was also demonstrated in Caenorhabditis elegans; how
Braz J Med Biol Res. Publicado em: 02/07/2018