Hpmc
Mostrando 1-12 de 110 artigos, teses e dissertações.
-
1. Alcoholmeter as a Simple and Accessible Way for Ethanol Determination in Alcohol-Based Hand Sanitizers
Expensive and complex methodologies are available to determine the ethanol concentration in alcohol gel samples. The aim of this article was to demonstrate that alcoholmeter could be used as an alternative method to determine ethanol in gel formulations. Alcohol gel samples were produced using: hydroxypropylmethylcellulose (HPMC), hydroxyethylcellulose (HEC)
J. Braz. Chem. Soc.. Publicado em: 2021-06
-
2. Defatted chia flour improves gluten-free bread nutritional aspects: a model approach
Abstract The gluten is a protein associated with a numerous food allergy cases. As the gluten-related disorders relates is increasing, the demand for gluten-free breads (GFB) has been also increasing. The aim of this study was to obtain a GFB with increased nutritional aspects and sensorially accepted. A Central Composite Rotatable Design (CCRD) 23 was emplo
Food Sci. Technol. Publicado em: 2020-06
-
3. Postharvest conservation of ‘Avalanche’ cut roses with hydroxypropyl methylcellulose-beeswax natural coating
RESUMO O uso de recobrimentos na pós-colheita de frutas e hortaliças é objeto de estudos há vários anos pela sua capacidade de prolongar a vida de prateleira de vegetais. No entanto, pouco se sabe acerca do uso destes recobrimentos na conservação pós-colheita de flores de corte. O objetivo deste trabalho foi avaliar o efeito de diferentes concentraç
Ciênc. agrotec.. Publicado em: 07/11/2019
-
4. Effect of wet mass on dextromethorphan hydrobromide matrix pellets
Dextromethorphan hydrobromide (DM) sustained release matrix pellets containing 10% w/w drug were prepared by an extrusion/spheronization technique. The effect of mixing different concentrations of ethyl cellulose (EC), hydroxypropyl methylcellulpse (HPMC K10), and Carbopol 934 with Avicel PH101 on the rheological properties of pellet wet mass was evaluated u
Braz. J. Pharm. Sci.. Publicado em: 08/04/2019
-
5. Influence of different formulation variables on the performance of transdermal drug delivery system containing tizanidine hydrochloride: in vitro and ex vivo evaluations
The present study was aimed at preparation of transdermal patches of tizanidine HCl, evaluation of the effect of polymers on in vitro release pattern of the drug, and the effect of permeation enhancers on the penetration of the drug through the rabbit skin. Various proportions of hydrophilic (HPMC) and hydrophobic (Eudragit L-100) polymers were used with PEG
Braz. J. Pharm. Sci.. Publicado em: 08/04/2019
-
6. Development and evaluation of multiparticulate biphasic system for the treatment of circadian diseases
Multiparticulate systems have biopharmaceutical advantages when compared to the monolithic systems, once they allow different patterns of drug release and can be used in different treatments. The aim of the present work was to develop a biphasic controlled release delivery system, using propranolol hydrochloride (PROP) that can be used for the treatment of c
Braz. J. Pharm. Sci.. Publicado em: 08/04/2019
-
7. Preparation and in vitro & in vivo evaluation of cephalexin matrix tablets
The purpose of the study is to develop cephalexin controlled-release matrix tablets by using lower proportions of release retardant polymer and to establish their in vitro & in vivo correlation. Tablets were compressed by incorporating polymers in a matrix form along with drug which prolong the drug release. Twelve formulations were prepared by mixing ethyl
Braz. J. Pharm. Sci.. Publicado em: 29/11/2018
-
8. Adenanthera pavonina GALACTOMANNAN FOR CONTROLLED DELIVERY OF RUTIN - A PRELIMINARY STUDY
Improving the development of modified release matrix systems strictly depends on selecting an appropriate agent capable of controlling the drug's release. In this study, Adenanthera pavonina galactomannan was investigated as a potential basis for developing a controlled release of rutin. This galactomannan was extracted, purified and characterized by GPC, NM
Quím. Nova. Publicado em: 2018-06
-
9. MELHORANDO A RESISTÊNCIA DE FILMES DE HIDROXIPROPIL METILCELULOSE/ AMIDO COM NANOCRISTAIS DE CELULOSE
RESUMO O interesse em nanocristais de celulose obtidos a partir de recursos naturais tem crescido principalmente devido a características que esses materiais fornecem quando inseridos em matrizes poliméricas. O presente estudo teve como objetivo avaliar o efeito da adição de nanocristais de celulose nas propriedades mecânicas dos biofilmes feitos a part
CERNE. Publicado em: 2017-12
-
10. In vitro evaluation of sustained released matrix tablets containing ibuprofen: a model poorly water-soluble drug
ABSTRACT A matrix system was developed that releases ibuprofen (IB) over a 12-hour period and the influence of the polymer type and concentration on the release rate of the drug was evaluated. Tablets containing different concentrations of Carbopol (CP), hydroxypropyl methylcellulose (HPMC), or ethyl cellulose (EC) were prepared using direct compression and
Braz. J. Pharm. Sci.. Publicado em: 2016-12
-
11. In vitro and in vivo evaluation of nano-based films for buccal delivery of zolpidem
Abstract Insomnia is becoming increasingly prevalent in the world general population. Therapies used by patients include over-the-counter therapies, herbal and dietary supplements, and pharmacological or nonpharmacological treatments. Among these, zolpidem is a pharmacological treatment popularly used for insomnia. Zolpidem is well tolerated and especially e
Braz. oral res.. Publicado em: 28/11/2016
-
12. Development and evaluation of bilayer tablets of combination of antibiotics for the treatment of sexually transmitted disease
ABSTRACT The present research work was envisaged to develop bilayer tablets to improve therapeutic efficacy of antibiotic combination for the treatment of sexually transmitted diseases. The combination of two antibiotics i.e. cefixime trihydrate and ofloxacin were used for the preparation of bilayer tablets which act against genito-urinary infections. The fo
Braz. J. Pharm. Sci.. Publicado em: 2016-09