Hot Plate Test
Mostrando 1-12 de 97 artigos, teses e dissertações.
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1. Analgesic and antiinflammatory activities of the essential oil from Artemisia sieberi Besser
The analgesic activity of Artemisia sieberi oil was assessed by acetic acid-induced writhing test and Eddy’s hot plate method; while the acute anti-inflammatory effect was investigated by inflammatory paw edema test in rats. The administration rout of the essential oil, standard drugs and the vehicle used in all assays was intraperitoneal injection. The 1
Braz. J. Pharm. Sci.. Publicado em: 20/12/2019
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2. Fractions of Selaginella convoluta (Arn.) Spring (Selaginellaceae) attenuate the nociceptive behavior events in mice
Resumo Selaginella convoluta é uma espécie popularmente conhecida como “jericó”, e usada na medicina popular como analgésica e anti-inflamatória. Este estudo teve como objetivo investigar em camundongos as atividades antinociceptiva e anti-inflamatória das frações hexânica (Sc-Hex) e clorofórmica (Sc-CHCl3) (100, 200 e 400 mg/kg) obtidas por pa
Braz. J. Biol.. Publicado em: 18/04/2019
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3. Experimental investigation of bolted stiffened end-plate and bolted flange-plate connections
Abstract This paper describes the experimental performance of the bolted stiffened end-plate (BSEP) and bolted flange-plate (BFP) connections using European hot-rolled profiles and built-up profiles. Four connections are designed and constructed according to FEMA-350 and are performed under cyclic loading. The influence of using different member profiles (Eu
Lat. Am. j. solids struct.. Publicado em: 21/03/2019
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4. Pre-clinical interaction of ayahuasca, a brew used in spiritual movements, with morphine and propofol
ABSTRACT Ayahuasca is a beverage with psychoactive properties used in religious and ceremonial rituals by some religious groups. The main active components of ayahuasca are dimethyltryptamine and the harmala alkaloids with β-carboline structure acting as monoamine oxidase A inhibitors. This combination produces a pronounced activation of serotonergic pathwa
Braz. J. Pharm. Sci.. Publicado em: 07/06/2018
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5. Analgesic effects of Marasmius androsaceus mycelia ethanol extract and possible mechanisms in mice
Marasmius androsaceus is a medicinal fungus mainly used to treat various forms of pain in China. This study investigated the analgesic effects of an ethanol extract of M. androsaceus (MAE) and its potential molecular mechanisms. Oral administration of MAE (50, 200, and 1000 mg/kg) had significant analgesic effects in an acid-induced writhing test, a formalin
Braz J Med Biol Res. Publicado em: 01/03/2018
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6. Possible mechanisms of antinociception of methanol extract of Melastoma malabathricum leaves
ABSTRACT Melastoma malabathricum L., Melastomaceae, has been traditionally used to relieve diverse pain-related ailments. The objectives of the present study were to determine the antinociceptive activity of methanol extract of M. malabathricum leaves and to elucidate the possible mechanisms of antinociception involved using various rats' models. The extract
Rev. bras. farmacogn.. Publicado em: 2016-10
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7. Antinociceptive effect of semi-purified petroleum ether partition of Muntingia calabura leaves
ABSTRACT Muntingia calabura L., Muntingiaceae, is a medicinal plant for various pain-related diseases. The aims of the present study were to determine the antinociceptive profile and to elucidate the possible mechanisms of antinociception of petroleum ether partition obtained from crude methanol extract of M. calabura leaves using various animal models. The
Rev. bras. farmacogn.. Publicado em: 2016-08
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8. Antinociceptive activity of Sargassum polyceratium and the isolation of its chemical components
Abstract Marine algae have been the focus of important studies over the past fifty years, with a considerable number of components important to chemists and taxonomists having been isolated and characterized. The scientific data available on Sargassum polyceratium are extremely limited. The objective of the present study was to evaluate the antinociceptive a
Rev. bras. farmacogn.. Publicado em: 2015-12
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9. Restoration of sensory dysfunction following peripheral nerve injury by the polysaccharide from culinary and medicinal mushroom, Hericium erinaceus (Bull.: Fr.) Pers. through its neuroregenerative action
Abstract Peripheral nerves have the unique capability to regenerate after injury. Insights into regeneration of peripheral nerves after injury may have implications for neurodegenerative diseases of the nervous system. We investigated the ability of polysaccharide from Hericium erinaceus mushroom in the treatment of nerve injury following peroneal nerve crus
Food Sci. Technol. Publicado em: 24/11/2015
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10. Oleanane-type triterpenoid: an anti-inflammatory compound of the roots Arrabidaea brachypoda
AbstractArrabidaea brachypoda Bureau, Bignoniaceae, known as "cipó-una", is widely used in traditional medicine in Southeastern and Northeastern Brazil for kidney stones and painful joints. This study was aimed at evaluating the anti-inflammatory proprieties of the oleanane-type triterpenoid 3β-estearioxy-olean-12-ene isolated from the roots of A. brachypo
Rev. bras. farmacogn.. Publicado em: 2015-06
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11. Toxicity and antinociceptive effects of Hamelia patens
Abstract Many medicinal herbs are used in folk medicine without taking into account their toxicity. Hamelia patens Jacq. (Rubiaceae), a Mexican endemic species, is used for the empirical treatment of pain. The aim of this work was to evaluate the toxicity and antinociceptive effects of ethanolic extracts of H. patens leaves. The toxicity of H. patens leaves
Rev. bras. farmacogn.. Publicado em: 2015-04
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12. Anti-inflammatory and antinociceptive activities of non-alkaloids fractions from Aconitum flavum in vivo
Aconitum flavum Hand.-Mazz., Ranunculaceae, has been used for the treatment of rheumatism, traumatic injury in folk and clinical medicine, but the alkaloids has high toxicity. This study was designed to investigate the acute toxicity, anti-inflammatory and antinociceptive activities of non-alkaloids fractions from A. flavum in rodents. The anti-inflammatory
Rev. bras. farmacogn.. Publicado em: 2015-02