History Of Genetics
Mostrando 1-12 de 89 artigos, teses e dissertações.
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1. When do we need to suspect maturity onset diabetes of the young in patients with type 2 diabetes mellitus?
ABSTRACT Objetivo: Maturity onset diabetes of the young (MODY) patients have clinical heterogeneity as shown by many studies. Thus, often it is misdiagnosed to type 1 or type 2 diabetes(T2DM). The aim of this study is to evaluate MODY mutations in adult T2DM patients suspicious in terms of MODY, and to show clinical and laboratory differences between these
Archives of Endocrinology and Metabolism. Publicado em: 2022
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2. Dysregulation in erythrocyte dynamics caused by SARS-CoV-2 infection: possible role in shuffling the homeostatic puzzle during COVID-19
Abstract Introduction The evolving COVID-19 pandemic became a hallmark in human history, not only by changing lifestyles, but also by enriching scientific knowledge on viral infection and its consequences. Objective Although the management of cardiorespiratory changes is pivotal to a favorable prognosis during severe clinical findings, dysregulation of oth
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
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3. Fabry disease: genetics, pathology, and treatment
SUMMARY Fabry disease (FD) is a recessive monogenic inheritance disease linked to chromosome X, secondary to mutations in the GLA gene. Its prevalence is estimated between 1:8,454 and 1:117,000 among males and is probably underdiagnosed. Mutations in the GLA gene lead to the progressive accumulation of globotriaosylceramide (Gb3). Gb3 accumulates in lysosome
Rev. Assoc. Med. Bras.. Publicado em: 13/01/2020
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4. The impact of maintenance on peri-implant health
Abstract Most of the literature evaluating dental implants focuses on implant survival, which is a limited proxy for the successful rehabilitation of patients with missing teeth. Success should include not only survival but also lack of mechanical, biological, and esthetics problems. A comprehensive review of local and systemic risk factors prior to implant
Braz. oral res.. Publicado em: 30/09/2019
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5. Liaisons dangereuses: cross-border gene flow and dispersal of insecticide resistance-associated genes in the mosquito Aedes aegypti from Brazil and French Guiana
BACKGROUND In recent years, South America has suffered the burden of continuous high impact outbreaks of dengue, chikungunya and Zika. Aedes aegypti is the main mosquito vector of these arboviruses and its control is the only solution to reduce transmission. OBJECTIVES In order to improve vector control it is essential to study mosquito population geneti
Mem. Inst. Oswaldo Cruz. Publicado em: 23/09/2019
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6. Clinical research challenges in rare genetic diseases in Brazil
Abstract Rare diseases are defined as conditions with a prevalence of no more than 6.5 per 10,000 people. Although each rare disease individually affects a small number of people, collectively, the 6,000 to 8,000 rare conditions (80% of them with genetic cause) affect around 8% of the world’s population. Research about the natural history and underlying pa
Genet. Mol. Biol.. Publicado em: 03/06/2019
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7. The golden age of Drosophila research at the Universidade de São Paulo (USP): a testimonial on the decades 1940-1950
This article is a testimonial written by the first author regarding the research work performed with Drosophila between 1943 and 1959, at the Departamento de Biologia Geral of the Universidade de São Paulo (USP), which permitted the building of a nucleus of excellence. This research work, focused on the systematics and population genetics of the Neotropical
Genet. Mol. Biol.. Publicado em: 2014
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8. Human molecular cytogenetics: from cells to nucleotides
The field of cytogenetics has focused on studying the number, structure, function and origin of chromosomal abnormalities and the evolution of chromosomes. The development of fluorescent molecules that either directly or via an intermediate molecule bind to DNA has led to the development of fluorescent in situ hybridization (FISH), a technology linking cytog
Genet. Mol. Biol.. Publicado em: 2014
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9. History of domestication and spread of Aedes aegypti - A Review
The adaptation of insect vectors of human diseases to breed in human habitats (domestication) is one of the most important phenomena in medical entomology. Considerable data are available on the vector mosquito Aedes aegypti in this regard and here we integrate the available information including genetics, behaviour, morphology, ecology and biogeography of t
Mem. Inst. Oswaldo Cruz. Publicado em: 2013
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10. Contribuições do uso do cinema para o ensino de ciências: tendências entre 1997 e 2009 / Contributions of using cinema for science education: trends between 1997 and 2009.
Taking into consideration the influence caused by the media in our society, this dissertation seeks to analyze qualitatively the academic production dealing with the use of Cinema with focus on teaching Science. For this purpose three databases were searched (ENPEC, CEDOC and SIBIUSP) in a specific time frame (1997 to 2009) and were based on a methodology ce
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 13/04/2012
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11. Genetics, evolution and conservation of Bromeliaceae
Bromeliaceae is a morphologically distinctive and ecologically diverse family originating in the New World. Three centers of diversity, 58 genera, and about 3,140 bromeliad species are currently recognized. We compiled all of the studies related to the reproductive biology, genetic diversity, and population structure of the Bromeliaceae, and discuss the evol
Genet. Mol. Biol.. Publicado em: 2012
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12. Vulnerability to type 2 diabetes and cardiovascular disease in relatives of diabetic patients / Vulnerabilidade ao diabetes mellitus tipo 2 e Ãs doenÃas cardiovasculares em familiares de pacientes diabÃticos
Considering that family history involves modifiable and not modifiable risk factors, it is assumed that besides genetics, behavioral factors in day-to-day family dynamics contributes to increase the risk of developing type 2 diabetes mellitus (T2DM) and cardiovascular diseases (CVD). Through the description of the set of dimensions involved in health-disease
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/07/2010