Heterogeneity
Mostrando 13-24 de 4011 artigos, teses e dissertações.
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13. Tandem Synthesis of Furanaphthoquinones via Enamines and Evaluation of Their Antiparasitic Effects against Trypanosoma cruzi
Furanaphthoquinones are well known in medicinal chemistry for exhibiting relevant structural heterogeneity and bioactivities. In this work, it was synthesized a series of furanaphthoquinones through a tandem reaction between lawsone (8) and cyclic ketones in the presence of morpholine. This strategy provides an efficient and general method for synthesizing f
Journal of the Brazilian Chemical Society. Publicado em: 2022
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14. Physicians’ income in Brazil: a study on information sources
SUMMARY OBJECTIVE: Data on physicians’ income are relevant for well-informed health policies, both due to their strategic role and the volume of resources that their activities represent to health systems. In Brazil, multiple sources of data measure the income of these professionals, each one with singularities that generate a complex and heterogeneous pi
Revista da Associação Médica Brasileira. Publicado em: 2022
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15. Identifying conceptions of the covalent bond: an analysis from a systematic review
The covalent bond is a classical topic in science education because it is fundamental to a considerable number of other concepts and by its ability to interpret several chemical phenomena. However, the process of learning this concept presents some difficulties discussed here. This article brings together the conceptions related to the covalent bond, identif
Química Nova. Publicado em: 2022
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16. Diabetes and bone
Abstract Globally, one in 11 adults has diabetes mellitus of which 90% have type 2 diabetes. The numbers for osteoporosis are no less staggering: 1 in 3 women has a fracture after menopause, and the same is true for 1 in 5 men after the age of 50 years. Aging is associated with several physiological changes that cause insulin resistance and impaired insulin
Archives of Endocrinology and Metabolism. Publicado em: 2022
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17. Adolescent depression and resting-state fMRI brain networks: a scoping review of longitudinal studies
The neurobiological factors associated with the emergence of major depressive disorder (MDD) in adolescence are still unclear. Previous cross-sectional studies have documented aberrant connectivity in resting-state functional magnetic resonance imaging (rs-fMRI) networks. However, whether these findings precede MDD onset has not been established. This scopin
Brazilian Journal of Psychiatry. Publicado em: 2022
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18. Effects of imipenem combined with glutamine in the treatment of severe acute pancreatitis with abdominal infection in mainland China: a meta-analysis
SUMMARY OBJECTIVE: The aim of this study was to explore the efficacy of imipenem combined with glutamine in the treatment of severe acute pancreatitis with abdominal infection in mainland China using meta-analysis. METHODS: We searched China National Knowledge Network, Wanfang Medical Network, Chinese Science Citation Database, PubMed, and Embase Databases
Revista da Associação Médica Brasileira. Publicado em: 2022
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19. Serum Cystatin C as a predictor of acute kidney injury in neonates: a meta-analysis
Abstract Objective: The objective of this meta-analysis is to evaluate the diagnostic value of serum Cystatin C in acute kidney injury (AKI) in neonates Sources: PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure (CNKI), and WanFang Database were searched to retrieve the literature related to the diagnostic value of C
Jornal de Pediatria. Publicado em: 2022
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20. Association between ventricular premature contraction burden and ventricular repolarization duration
SUMMARY OBJECTIVE: Premature ventricular contraction is generally known as benign in the absence of structural heart disease; however, premature ventricular contraction-induced left ventricular systolic dysfunction or ventricular arrhythmias are defined in some cases. Ventricular repolarization duration differs between myocardial cells, which causes myocard
Revista da Associação Médica Brasileira. Publicado em: 2022
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21. Perceived racism or racial discrimination and the risk of adverse obstetric outcomes: a systematic review
ABSTRACT BACKGROUND: Racial disparities are differences among distinct subgroups of the human species; biologically, there are no scientifically proven reasons for them to exist. OBJECTIVE: To assess the impact of racism or racial discrimination on obstetric outcomes. DESIGN AND SETTING: Systematic review conducted at a tertiary/academic hospital. METHOD
Sao Paulo Medical Journal. Publicado em: 2022
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22. When do we need to suspect maturity onset diabetes of the young in patients with type 2 diabetes mellitus?
ABSTRACT Objetivo: Maturity onset diabetes of the young (MODY) patients have clinical heterogeneity as shown by many studies. Thus, often it is misdiagnosed to type 1 or type 2 diabetes(T2DM). The aim of this study is to evaluate MODY mutations in adult T2DM patients suspicious in terms of MODY, and to show clinical and laboratory differences between these
Archives of Endocrinology and Metabolism. Publicado em: 2022
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23. Prone ventilation in intubated COVID-19 patients: a systematic review and meta-analysis
Abstract Background The efficacy and safety profiles of prone ventilation among intubated Coronavirus Disease 2019 (COVID-19) patients remain unclear. The primary objective was to examine the effect of prone ventilation on the ratio of arterial partial pressure of oxygen to fraction of inspired oxygen (PaO2/FiO2) in intubated COVID-19 patients. Methods Dat
Brazilian Journal of Anesthesiology. Publicado em: 2022
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24. The risk of organ-based comorbidities in psoriasis: a systematic review and meta-analysis
Abstract Background: The close relationship between psoriasis and concomitant diseases is widely accepted. However, a comprehensive analysis of organ-based comorbidities in psoriasis is still lacking. Objective: The authors aimed to present the risk of organ-based comorbidities in psoriasis by comparing the general population. Methods: The authors retriev
Anais Brasileiros de Dermatologia. Publicado em: 2022