Hemostatic Disorders
Mostrando 1-10 de 10 artigos, teses e dissertações.
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1. Kn-Ba: a novel serine protease isolated from Bitis arietans snake venom with fibrinogenolytic and kinin-releasing activities
Abstract Background: Bitis arietans is a venomous snake found in sub-Saharan Africa and in parts of Morocco and Saudi Arabia. The envenomation is characterized by local and systemic reactions including pain, blistering, edema and tissue damage, besides hemostatic and cardiovascular disturbances, which can cause death or permanent disabilities in its victims
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 24/01/2019
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2. BaltDC: purification, characterization and infrared spectroscopy of an antiplatelet DC protein isolated from Bothrops alternatus snake venom
Abstract Background: Snake venoms are a complex mixture of proteins, organic and inorganic compounds. Some of these proteins, enzymatic or non-enzymatic ones, are able to interact with platelet receptors, causing hemostatic disorders. The possible therapeutic potential of toxins with antiplatelet properties may arouse interest in the pharmacological areas.
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 08/02/2018
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3. Thrombin generation assays for global evaluation of the hemostatic system: perspectives and limitations
Abstract The existing techniques to evaluate hemostasis in clinical laboratories are not sensitive enough to detect hypercoagulable and mild hypocoagulable states. Under different experimental conditions, the thrombin generation test may meet these requirements. This technique evaluates the overall balance between procoagulant and anticoagulant forces and ha
Rev. Bras. Hematol. Hemoter.. Publicado em: 2017-09
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4. Hemostatic disorders induced by skin contact with Lonomia obliqua (Lepidoptera, Saturniidae) caterpillars
ABSTRACT Patients envenomed by Lonomia sp caterpillars initially experience a mild burning pain, headache, nausea, vomiting, and skin and mucosal hemorrhages. Some patients can rapidly progress to a severe coagulopathy that presents as visceral or intracerebral hemorrhaging. We studied the hemostatic alterations that occurred in 14 patients who were envenome
Rev. Inst. Med. trop. S. Paulo. Publicado em: 20/04/2017
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5. Marcadores do sistema hemostático e sua associação com parâmetros clínicos e laboratoriais em mulheres com síndrome dos ovários policísticos = : Markers of the hemostatic system and their association with clinical and laboratory parameters in women with polycystic ovary syndrome / Markers of the hemostatic system and their association with clinical and laboratory parameters in women with polycystic ovary syndrome
Introduction: Few studies have been conducted on hemostatic disorders in polycystic ovary syndrome (PCOS). In women with PCOS, thromboembolic risk factors such as obesity, hyperandrogenism and insulin resistance are often present, indirectly suggesting a greater probability of coagulation disorders. Objective: To evaluate some markers of the hemostatic syste
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 03/10/2012
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6. Development of a sensitive enzyme immunoassay (ELISA) for specific identification of Lachesis acrochorda venom
The snake genus Lachesis provokes 2 to 3% of snakebites in Colombia every year. Two Lachesis species, L. acrochorda and L. muta, share habitats with snakes from another genus, namely Bothrops asper and B. atrox. Lachesis venom causes systemic and local effects such as swelling, hemorrhaging, myonecrosis, hemostatic disorders and nephrotoxic symptoms similar
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2012
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7. Transtornos da hemostasia em cães azotêmicos / Hemostatic disorders in azotemic dogs
A uremia é uma desordem sistêmica que pode estar associada à disfunção plaquetária adquirida, levando a alterações na hemostasia primária. Vários modelos de interferência entre a uremia e a falha na hemostasia já foram propostos, porém o mecanismo exato é desconhecido, e a tendência ao sangramento parece ser de origem multifatorial. O teste do
Publicado em: 2011
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8. Evaluation of fibrinolysis and factor XIII some parameters in patients with spontaneous deep venous trombosis and hemorrhagic disease / Avaliação de alguns parametros da fibrinolise e do fator XIII em pacientes com trombose venosa profunda espontanea e doença hemorragica
In a parcel of patients with hemorrhagic or thrombotic clinical picture, none etiologic diagnosis is established. The patients with hemorrhagic desorder, many times important, can present all inside the screening tests and specific dosage of factors of the coagulation of the values of normality. Note: the complete abstract is avaiable with the link or full e
Publicado em: 2008
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9. Value of the preoperative history as an indicator of hemostatic disorders.
Eighty-three general surgical patients completed the standardized bleeding history questionnaire, and screening tests of platelet counts, prothrombin times, partial thromboplastin times, and Ivy bleeding times were done on these patients. Fifty-two per cent had undergone previous operation; 25% described symptoms of potential hemostatic disorders and seven p
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10. Influence of Cephalosporin Antibiotics on Blood Coagulation and Platelet Function
Administration of cephalothin to normal volunteers in maximal doses of 300 mg/kg per day resulted in a combined defect of platelet function and blood coagulation. No such abnormalities were evident after infusion of cefazolin or cephapirin at a maximal dosage of 200 mg/kg per day. The observed thrombocytopathy was similar to but less severe than that induced