Hemorrhagic Cystitis
Mostrando 13-24 de 24 artigos, teses e dissertações.
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13. A model of hemorrhagic cystitis induced with acrolein in mice
Acrolein is a urinary metabolite of cyclophosphamide and ifosfamide, which has been reported to be the causative agent of hemorrhagic cystitis induced by these compounds. A direct cytotoxic effect of acrolein, however, has not yet been demonstrated. In the present study, the effects of intravesical injection of acrolein and mesna, the classical acrolein chem
Brazilian Journal of Medical and Biological Research. Publicado em: 25/09/2006
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14. Detection of cytomegalovirus and polyomavirus in hemorrhagic cystitis in allogenic recipients in haematopoetic stem cell transplantation / Detecção do citomegalovirus e poliomavirus na cistite hemorragica em transplantados alogenicos de celulas progenitoras hematopoeticas
A reativação da infecção pelo Citomegalovírus humano (HCMV) e pelo Poliomavírus (BKV) no uroendotélio, vem sendo relacionada a complicações como a Cistite Hemorrágica (CH) em receptores de transplante de células progenitoras hematopoéticas (TCPH), o que representa um fator de risco para estes pacientes. Este estudo prospectivo de 41 receptores de
Publicado em: 2006
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15. Methicillin Hemorrhagic Cystitis
Interstitial nephritis is a recognized complication of methicillin therapy. Hemorrhagic cystitis due to methicillin has not been emphasized. Evidence of hemorrhagic cystitis developed in six patients receiving methicillin therapy and was confirmed by cystoscopy in three of them.
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16. Association between a High BK Virus Load in Urine Samples of Patients with Graft-Versus-Host Disease and Development of Hemorrhagic Cystitis after Hematopoietic Stem Cell Transplantation
BK virus (BKV) load in urine alone or in combination with acute graft-versus-host disease (GVHD) was correlated to development of hemorrhagic cystitis (HC). BKV load in combination with acute GVHD discriminated the best, while BKV and viral load alone, but not GVHD, still showed predictive ability for HC.
American Society for Microbiology.
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17. Increased Sensitivity of Glutathione S-Transferase P-Null Mice to Cyclophosphamide-Induced Urinary Bladder Toxicity
Hemorrhagic cystitis and diffuse inflammation of the bladder, common side effects of cyclophosphamide (CY) treatment, have been linked to the generation of acrolein derived from CY metabolism. Metabolic removal of acrolein involves multiple pathways, which include reduction, oxidation, and conjugation with glutathione. Herein, we tested the hypothesis that g
The American Society for Pharmacology and Experimental Therapeutics.
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18. PCR Detection of Adenovirus in a Bone Marrow Transplant Recipient: Hemorrhagic Cystitis as a Presenting Manifestation of Disseminated Disease
Adenoviruses (AdV), causing fatal disseminated infections in bone marrow transplant (BMT) recipients, are associated not only with hemorrhagic cystitis (HC) but also with hepatitis, conjunctivitis, and viral interstitial pneumonia. The importance of this virus as a cause of disseminated disease, however, has remained underappreciated. AdV infection has been
American Society for Microbiology.
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19. Suppression of Reticuloendothelial Function in the Rat with Cyclophosphamide
Effects of cyclophosphamide immunosuppressive therapy upon reticuloendothelial function in the rat have been studied. Numerous side effects including leukopenia, hematuria, diarrhea, hemorrhagic cystitis, and petechial hemorrhage in the lungs and the small bowel were observed. Studies utilizing 32P-labeled bacteria revealed no change in the ability of the li
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20. Pharmacokinetics of oral fluconazole when used for prophylaxis in bone marrow transplant recipients.
The pharmacokinetics of fluconazole was investigated in 20 bone marrow transplant patients following oral administration of 200 mg of this drug. Blood samples were collected from each patient at different time intervals within 48 h after the first dose, and fluconazole was measured in plasma by high-performance liquid chromatography with UV detection. Urine
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21. Linker scan analysis of the early regulatory region of human papovavirus BK.
BK virus (BKV) is a human papovavirus which latently infects a majority of the world population. Reactivation of this virus is associated with acute hemorrhagic cystitis, and BKV DNA has been found in human tumor tissue. BKV is one of many highly homologous papovaviruses, including simian virus 40 and JC virus, which display distinct host and cell-type speci
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22. Detection and Differentiation of Human Polyomaviruses JC and BK by LightCycler PCR
Human polyomaviruses JC and BK may cause several clinical manifestations in immunocompromised hosts, including progressive multifocal leukoencephalopathy and hemorrhagic cystitis. Molecular detection by PCR is recognized as a sensitive and specific method for detecting human polyomaviruses in clinical samples. In this study, a real-time PCR assay using the L
American Society for Microbiology.
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23. Activities of various compounds against murine and primate polyomaviruses.
Polyomavirus infections in humans are due to BK virus (BKV) and JC virus (JCV). Diseases associated with human polyomaviruses occur mostly in immunocompromised adults, e.g., progressive multifocal leukoencephalopathy (PML), caused by JCV, in AIDS patients and hemorrhagic cystitis and uretral stenosis, caused by BKV, in transplant recipients. No therapy is av
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24. Disseminated Aspergillosis Caused by Aspergillus ustus in a Patient Following Allogeneic Peripheral Stem Cell Transplantation
The first case of disseminated aspergillosis caused by Aspergillus ustus in an allogeneic peripheral stem cell transplant patient is described. The patient, a 46-year-old female with a history of myelodysplastic syndrome, underwent high-dose chemotherapy and total body irradiation prior to transplantation. She was released from the hospital 49 days posttrans
American Society for Microbiology.