Heat Labile Toxins
Mostrando 1-12 de 103 artigos, teses e dissertações.
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1. Production and characterization of recombinant chimeras C and D of Clostridium botulinum / Produção e caracterização de quimeras recombinantes C e D de Clostridium botulinum
Bovine Botulism is a lethal intoxication caused by the ingestion of the neurotoxins produced by Clostridium botulinum types C and D that inhibit the release of acetylcholine at the neuromuscular junction leading to death by flaccid paralysis. It produces important economic losses, being a major cause of casualties in cattle in several regions of Brazil. The
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/08/2012
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2. Enterotoxins, colonization factors, serotypes and antimicrobial resistance of enterotoxigenic Escherichia coli (ETEC) strains isolated from hospitalized children with diarrhea in Bolivia
Enterotoxigenic Escherichia coli (ETEC) is recognized as the main cause of bacterial diarrhoea among children in Asia, Africa and Latin America but less investigated in Bolivia. OBJECTIVE: To determine the relation between enterotoxins, CFs and serotypes as well as the antimicrobial resistance patterns in a set of ETEC isolates collected from hospitalized ch
Brazilian Journal of Infectious Diseases. Publicado em: 2011-04
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3. The prevalence of enterotoxigenic E. coli isolated from the stools of children aged 0-10 years with diarrhea in mid-anatolia region, Turkey
The stool samples from 245 patients with diarrhea were tested for heat labile toxin (LT) and heat stable toxins (ST) by passive latex agglutination and enzyme immunoassay methods respectively. Twelve (4.9%) enterotoxigenic E. Coli ETEC strains were isolated. Five strains (2%) expressed ST, and 7 (2.8%) expressed LT.
Brazilian Journal of Microbiology. Publicado em: 2011-03
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4. Pesquisa de genes de resistência a antimicrobianos beta-lactâmicos e de enterotoxina em cepas de Staphylococcus aureus presentes em amostras de alimentos / Search of antimicrobial beta-lactam resistance genes and enterotoxin genes in Staphylococcus aureus strains present in food samples
Introduction: Staphylococcus aureus are a bacterium that causes various types of diseases. There are two major aggravating to its presence: the toxins production and antimicrobial resistance. S. aureus produce heat-labile enterotoxina that, when present in food, can lead to poisoning of those who consume. This specie is also known to easily respond adaptivel
Publicado em: 2010
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5. Avaliação das propriedades imunomoduladoras de toxinas termo-lábeis do tipo II produzidas por Escherichia coli enterotoxigênica (ETEC) administradas por via transcutânea. / Evaluation of the immunomodulatory properties of type II heat-labile toxins produced by enterotoxigenic Escherichia coli (ETEC) administered by transcutaneous route.
Heat-labile toxins expressed by enterotoxigenic Escherichia coli (LT-I, LT-IIa and LT-IIb) are potent systemic and mucosal adjuvants. These proteins have low identity (<14%) in their B subunits and bind to different receptors, which may result in differential biological properties. The objective of this work was to evaluate the immune response induced by LT-
Publicado em: 2009
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6. Purificação e caracterização de uma toxina enterotóxica, citotóxina e letal produzida por amostras de Plesiomonas shigelloides isoladas de água de rio. / Purification and caracterization of an enterotoxic, cytotoxic and lethal toxin produced by Plesiomonas shigelloides isolated from river water.
Plesiomonas shigelloides is a ubiquous microorganism recognized as putative human and animal enteropathogen. Production of toxins has been related to their role in pathogenicity. At previous studies we detected a cytotoxin, named LCF (Lethal Citotoxic Factor) active on a variety of cells, causing intensive intracellular vacuolation and nuclear condensation,
Publicado em: 2008
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7. Frequency of Escherichia coli strains producing heat-labile toxin or heat-stable toxin or both in children with and without diarrhea in São Paulo.
Enterotoxigenic Escherichia coli strains were isolated from 32 (13.4%) of 245 children with diarrhea and from 11 (11.4%) of 96 children of the control group. Strains producing heat-labile toxin were found more frequently in normal children than in children with diarrhea. Strains producing heat-stable toxin and both heat-labile and heat-stable toxins were iso
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8. Relationship between enterotoxin production and serotype in enterotoxigenic Escherichia coli.
We examined the relationship between serotype and enterotoxin production in 109 enterotoxigenic Escherichia coli strains isolated from 109 patients with severe cholera-like diarrhea in Dacca, Bangladesh. Of 69 strains producing both heat-labile and heat-stable toxins, 59 (86%) belonged to the one of four O serogroups, and 56 (81%) of these strains belonged t
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9. Heat-labile enterotoxin production in isolates from a shipboard outbreak of human diarrheal illness.
As reported elsewhere, an enterotoxigenic strain of Escherichia coli serotype O25:K98:NM was epidemiologically incriminated as the etiological agent in a shipboard outbreak of diarrheal illness. This enterotoxigenic E. coli strain and possibly other enteric isolates were found to produce heat-labile toxin and not heat-stable toxin. Since previous genetic ana
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10. In vitro formation of hybrid toxins between subunits of Escherichia coli heat-labile enterotoxin and those of cholera enterotoxin.
Heat-labile enterotoxin (LT) was purified from cells of enterotoxigenic Escherichia coli isolated from a patient with traveller's diarrhea. Purified LT was separated into A and B subunits by treatment with 6 M urea solution in 0.1 M propionic acid (pH 4.0). Biologically active toxin was reconstituted from isolated A and B subunits of LT. Hybrid toxins with b
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11. Simultaneous detection of Escherichia coli heat-stable and heat-labile enterotoxin genes with a single RNA probe.
A single RNA probe was synthesized and used to detect simultaneously the methanol-soluble heat-stable enterotoxin and heat-labile enterotoxin genes in Escherichia coli strains. The results with the biotinylated or radioactive probe correlated 100% with the biological assay results for both toxins. The RNA probe detected the three known heat-stable enterotoxi
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12. Protection against challenge with Escherichia coli heat-labile enterotoxin by immunization of rats with cholera toxin/toxoid.
Rats were used to study dose-response curves to intestinal challenge with cholera toxin or Escherichia coli heat-labile enterotoxin. Prior immunization with cholera toxin/toxoid induced significant and equal protection against both toxins.