Hair Cells
Mostrando 1-12 de 476 artigos, teses e dissertações.
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1. Scanning electron microscopy of panitumumab-induced eyelash and hair alterations - Pili canaliculi
Abstract Panitumumab is a monoclonal antibody against the epidermal growth factor receptor used in metastatic colorectal cancer; in addition to tumor cells, it acts on epidermal keratinocytes and on the outer root sheath and presents skin toxicity in up to 90% of cases. A scanning electron microscope was used to examine the eyelashes and hairs of a 65-year-o
Anais Brasileiros de Dermatologia. Publicado em: 2022
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2. The Induction of Hypothyroidism during Gestation Decreases Outer Hair Cell Motility in Rat Offspring
Abstract Introduction Perinatal hypothyroidism has a negative repercussion on the development and maturation of auditory system function. However, its long-term effect on auditory function remains unsettled. Objective To evaluate the effect of prenatal hypothyroidism on the auditory function of adult offspring in rats. Methods Pregnant Wistar rats were gi
International Archives of Otorhinolaryngology. Publicado em: 2022
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3. The circadian timing of noise exposure influences noise-induced inflammatory responses in the mouse cochlea
Abstract Introduction: Noise-induced hearing loss is one of the most common forms of sensorineural hearing loss. Nevertheless, the mechanisms of noise-induced hearing loss are still not fully understood. Objective: To investigate the dynamics of inflammatory responses in the mammalian cochlea following noise trauma at two different times, once during the l
Brazilian Journal of Otorhinolaryngology. Publicado em: 2022
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4. Retinoic acid induces differentiation of cochlear neural progenitor cells into hair cells
Resumo Introdução: As células progenitoras da orelha interna têm potencial para diferenciação multidirecional. O ácido retinoico é uma condição importante para o desenvolvimento da orelha interna. O bloqueio da via de sinalização do ácido retinoico no órgão de Corti pode reduzir significativamente o número de células ciliadas. Portanto, acr
Brazilian Journal of Otorhinolaryngology. Publicado em: 2022
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5. The Ototoxicity of Chloroquine and Hydroxychloroquine: A Systematic Review
Abstract Introduction Chloroquine and hydroxychloroquine are antimalarial drugs widely used in the treatment of rheumatic diseases. With the global pandemic caused by the new coronavirus, there was an increase in the prescription of these drugs, which led to a major concern regarding their ototoxic effects. Objectives The objective of the present study was
International Archives of Otorhinolaryngology. Publicado em: 2022
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6. Is the Level of Noise in a School Environment be Harmful to the Hearing of Teachers?
Abstract Introduction The excessive noise observed in the school environment can cause damages or losses to the learning process as well as risks to the health of teachers and students, such as physical, mental and social impairments, including, among them, hearing loss. Objective To assess otoacoustic emissions in teachers and determine whether classroom
Int. Arch. Otorhinolaryngol.. Publicado em: 2020-12
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7. Histopathological changes in epithelium of hair follicles and acrosyringium caused by measles in child,
Abstract Some epidermal alterations in measles has been described, such as keratinocytes apoptotic, parakeratosis, giant-cell formation, intranuclear and cytoplasmic inclusions, dyskeratosis, spongiosis, and intracellular edema. The authors report for the first time in human a case of measles with the presence of multinucleated giant cells in the hair follic
An. Bras. Dermatol.. Publicado em: 2020-03
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8. Otoprotection Mechanisms Against Oxidative Stress Caused by Cisplatin
Abstract Introduction Cisplatin damages the auditory system and is related to the generation of free radicals. Glutathione peroxidase is an endogenous free radicals remover. Objective To investigate the mechanisms involved in otoprotection by N-acetylcys- teine through the expression of glutathione peroxidase in outer hair cells from rats treated with ci
Int. Arch. Otorhinolaryngol.. Publicado em: 2020-03
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9. International Archives of Otorhinolaryngology is now Indexed in Emerging Sources Citation Index of Web of Science
Abstract Introduction Cisplatin damages the auditory system and is related to the generation of free radicals. Glutathione peroxidase is an endogenous free radicals remover. Objective To investigate the mechanisms involved in otoprotection by N-acetylcys- teine through the expression of glutathione peroxidase in outer hair cells from rats treated with ci
Int. Arch. Otorhinolaryngol.. Publicado em: 2020-03
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10. Auditory findings associated with Zika virus infection: an integrative review
Resumo Introdução: Possíveis associações entre a infecção pelo Zika vírus e perda auditiva foram observadas durante a epidemia nas Américas. Objetivo: Descrever as alterações auditivas, a patogênese e as recomendações de seguimento em indivíduos com infecção por Zika vírus pré-natal ou adquirida. Método: Uma pesquisa bibliográfica foi
Braz. j. otorhinolaryngol.. Publicado em: 07/11/2019
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11. The Effects of Riluzole on Cisplatin-induced Ototoxicity
Abstract Introduction Riluzole (2-amino-6-trifluoromethoxy benzothiazole) is known as a neuroprotective, antioxidant, antiapoptotic agent. It may have beneficial effects on neuronal cell death due to cisplatin-induced ototoxicity. Objective To evaluate the effect of riluzole on cisplatin-induced ototoxicity in guinea pigs. Methods Twenty-four guinea pi
Int. Arch. Otorhinolaryngol.. Publicado em: 07/10/2019
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12. Stem-cell therapy for hearing loss: are we there yet?
Resumo Introdução: Nos mamíferos, as células ciliadas e os neurônios auditivos não apresentam capacidade regenerativa. Assim, os danos a esses tipos celulares são permanentes e levam à perda auditiva. Contudo, como não há tratamento que restabeleça a função auditiva, as terapias regenerativas utilizando células-tronco representam uma alternati
Braz. j. otorhinolaryngol.. Publicado em: 29/08/2019