Gut On A Chip
Mostrando 1-3 de 3 artigos, teses e dissertações.
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1. New methodologies for old problems: tridimensional gastrointestinal organoids and guts-on-a-chip
RESUMO Objetivos: A presente revisão visou apresentar uma abordagem crítica dos avanços metodológicos e experimentais referentes a modelos de cultura celular tridimensionais no âmbito do sistema gastrintestinal. Métodos: Foi realizada revisão da literatura com ênfase nos principais artigos publicados na área. Resultados principais: São apresenta
J. Coloproctol. (Rio J.). Publicado em: 2018-03
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2. Effects of receptor dimerization on the interaction between the class I major histocompatibility complex-related Fc receptor and IgG.
The neonatal Fc receptor (FcRn) transports maternal IgG from ingested milk in the gut to the bloodstream of newborn mammals. An FcRn dimer was observed in crystals of the receptor alone and of an FcRn-Fc complex, but its biological relevance was unknown. Here we use surface plasmon resonance-based biosensor assays to assess the role of FcRn dimerization in I
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3. Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury
We have identified cellular and molecular features of the stem cell niche required for marked amplification of mouse colonic epithelial progenitors (ColEPs) that occurs in response to wounding of the epithelium with dextran sodium sulfate. This regenerative response in areas adjacent to breaches in the epithelial barrier depends on the gut microbiota because
National Academy of Sciences.