Guanidine
Mostrando 1-12 de 486 artigos, teses e dissertações.
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1. Development of an Extraction Protocol for Fetal Sexing from the Fourth Week of Gestation by Real Time PCR
Abstract Low number of fetal cells in maternal blood limited the use of fetal materials in diagnostic and clinical applications. This research developed a technology which allowed the extraction of fetal DNA by a non-invasive method that offers no risk to the mother or fetus. A total of 132 pregnant women participated in this inquiry. The DNA extraction was
Braz. arch. biol. technol.. Publicado em: 24/10/2019
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2. Antibacterial, chemical and physical properties of sealants with polyhexamethylene guanidine hydrochloride
Abstract The aim of this study was to evaluate the influence of polyhexamethylene guanidine hydrochloride (PHMGH) in the physico-chemical properties and antibacterial activity of an experimental resin sealant. An experimental resin sealant was formulated with 60 wt.% of bisphenol A glycol dimethacrylate and 40 wt.% of triethylene glycol dimethacrylate with a
Braz. oral res.. Publicado em: 18/03/2019
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3. An alternative storage method for characterization of the intestinal microbiota through next generation sequencing
ABSTRACT Gut microbiota has been the subject of various molecular studies mainly due to its importance and wide-ranging relationships with human hosts. However, the storage of fecal samples prior to DNA extraction is critical when characterizing the composition of intestinal microbiota. Therefore, we aimed to understand the effects of different fecal storage
Rev. Inst. Med. trop. S. Paulo. Publicado em: 29/11/2018
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4. Conformational analysis of Pneumococcal Surface Antigen A (PsaA) upon zinc binding by fluorescence spectroscopy
ABSTRACT PsaA (pneumococcal surface antigen A) is a S. pneumoniae virulence factor that belongs to the metal transport system. The Manganese PsaA binding has been associated with oxidative stress resistance becoming a pivotal element in the bacteria virulence. It has been shown that Zinc inhibits the Manganese acquisition and promotes bacteria toxicity. We h
An. Acad. Bras. Ciênc.. Publicado em: 25/06/2018
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5. Heterologous expression, protein folding and antibody recognition of a neurotoxin from the Mexican coral snake Micrurus laticorallis
Abstract Background The cysteine-rich neurotoxins from elapid venoms are primarily responsible for human and animal envenomation; however, their low concentration in the venom may hamper the production of efficient elapid antivenoms. Therefore, the aim of the present study was to produce fully active elapid neurotoxic immunogens for elapid antivenom produc
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 13/10/2016
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6. SULFONIC ACID-FUNCTIONALIZED LUS-1: AN EFFICIENT CATALYST FOR ONE-POT SYNTHESIS OF 2,4-DIAMINO PYRIMIDINE-5-CARBONITRILE DERIVATIVES
An efficient acidic functionalization of mesoporous silica LUS-1 (Laval University Silica) and its application as a recyclable heterogeneous catalyst in the synthesis of 2,4-diamino pyrimidine-5-carbonitriles via condensation reaction of aromatic aldehydes, malononitrile and guanidine carbonate in solvent-free condition has been reported. This green method o
Quím. Nova. Publicado em: 2016-09
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7. Synthesis, in vitro Antiproliferative and Anti-Mycobacterium tuberculosis Activities of Novel β-Carboline Derivatives
A series of β-carboline derivatives with amino or guanidinium were synthesized and evaluated in vitro against anti-Mycobacterium tuberculosis and for antiproliferative activities against nine human cancer cell lines. The compounds 1-(4-hydroxyphenyl)-3-carboxamide(ethylamine) β-carboline (24.9 µg mL-1) and 1-(4-methoxyphenyl)-3-carboxamide(ethylamine) β-
J. Braz. Chem. Soc.. Publicado em: 2016-08
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8. Enhanced Production of Vitamin K2 from Bacillus subtilis (natto)by Mutation and Optimization of the Fermentation Medium
The aim of this study was to enhance the production of vitamin K2 by using N-methyl-N-nitro-N-nitroso-guanidine (NTG) and low energy ion beam implantation and optimizing the fermentation medium. Mutation resulted in 1.66-fold higher production of vitamin K2 than that of the parentl strain. The production by the mutant BN-P15-11-1was increased 55% and reached
Braz. arch. biol. technol.. Publicado em: 2014-08
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9. Dft theoretical study of energetic nitrogen-rich C4N6H8-n(NO2)n derivatives
Density functional theory (DFT) calculations at the B3LYP/6-31G** theoretical level were performed for a series of guanidine-fused bicyclic skeleton derivatives C4N6H8-n(NO2)n (n = 1 - 6). The heats of formation (HOFs) were calculated by isodesmic reactions, and the detonation properties were evaluated using the Kamlet - Jacobs equations. The bond dissociati
Quím. Nova. Publicado em: 2014
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10. Neural restrictive silencer factor and choline acetyltransferase expression in cerebral tissue of Alzheimer's Disease patients: a pilot study
Decreased Choline Acetyltransferase (ChAT) brain level is one of the main biochemical disorders in Alzheimer's Disease (AD). In rodents, recent data show that the CHAT gene can be regulated by a neural restrictive silencer factor (NRSF). The aim of the present work was to evaluate the gene and protein expression of CHAT and NRSF in frontal, temporal, entorhi
Genet. Mol. Biol.. Publicado em: 2013
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11. Efeito do fluoreto no osso de camundongos com diferentes susceptibilidades genéticas à fluorose: uma análise proteômica / Effect of fluoride on bone of mice with different genetic susceptibilities to fluorosis: a proteomic analysis
Genetic factors have been shown to influence bone and enamel responses to fluoride (F), but the molecular mechanisms involved remain unclear. In this study, a label-free proteomics approach was employed to identify and evaluate changes in bone protein expression of two mouse strains with different susceptibilities to fluorosis (A/J a susceptible strain, 129P
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 05/06/2012
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12. Systematic mutagenesis method for enhanced production of bacitracin by Bacillus licheniformis mutant strain UV-MN-HN-6
The purpose of the current study was intended to obtain the enhanced production of bacitracin by Bacillus licheniformis through random mutagenesis and optimization of various parameters. Several isolates of Bacillus licheniformis were isolated from local habitat and isolate designated as GP-35 produced maximum bacitracin production (14±0.72 IU ml-1). Bacitr
Brazilian Journal of Microbiology. Publicado em: 2012-03