Graves Ophthalmopathy
Mostrando 1-12 de 34 artigos, teses e dissertações.
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1. Proptosis is associated with thiol-disulfide in patients with Graves’ ophthalmopathy
ABSTRACT Objective: Graves’ ophthalmopathy (GO) is a vision-threatening finding observed in approximately half of Graves’ disease patients. The pathophysiology of GO is unclear, and one of the suspected factors is oxidative stress. In our study, we compared the relationship between proptosis and SH-SS in patients diagnosed with GO. Materials and method
Archives of Endocrinology and Metabolism. Publicado em: 2022
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2. Thyroid surgery – Does the scar matter?
ABSTRACT This position statement was prepared to guide endocrinologists on the best approach to managing thyroid disorders during the coronavirus disease (COVID-19) pandemic. The most frequent thyroid hormonal findings in patients with COVID-19, particularly in individuals with severe disease, are similar to those present in the non-thyroidal illness syndrom
Arch. Endocrinol. Metab.. Publicado em: 2021-06
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3. Management of thyroid disorders during the COVID-19 outbreak: a position statement from the Thyroid Department of the Brazilian Society of Endocrinology and Metabolism (SBEM)
ABSTRACT This position statement was prepared to guide endocrinologists on the best approach to managing thyroid disorders during the coronavirus disease (COVID-19) pandemic. The most frequent thyroid hormonal findings in patients with COVID-19, particularly in individuals with severe disease, are similar to those present in the non-thyroidal illness syndrom
Arch. Endocrinol. Metab.. Publicado em: 2021-06
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4. Graves’ ophthalmopathy: low-dose dexamethasone reduces retinoic acid receptor-alpha gene expression in orbital fibroblasts
ABSTRACT Objective: Graves’ ophthalmopathy (GO) is an autoimmune disease that leads to ocular proptosis caused by fat accumulation and inflammation, and the main treatment is corticosteroid therapy. Retinoid acid receptor-alpha (RARα) seems to be associated with inflammation and adipocyte differentiation. This study aimed to assess the effect of glucocor
Arch. Endocrinol. Metab.. Publicado em: 17/05/2018
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5. Serum selenium and selenoprotein-P levels in autoimmune thyroid diseases patients in a select center: a transversal study
ABSTRACT Objective: Selenium (Se) supplementation has been used to help prevent the progression of Graves’ ophthalmopathy (GO) and autoimmune thyroid diseases (AITD) patients. We investigated Se serum and selenoprotein P (SePP) levels in Graves’ disease (GD) with and without GO, Hashimoto's thyroiditis (HT) patients and in 27 control individuals (C). S
Arch. Endocrinol. Metab.. Publicado em: 2017-12
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6. Related quality of life questionnaire specific to dysthyroid ophthalmopathy evaluated in a population of patients with Graves’ disease
ABSTRACT Objective The aim of this study was to measure quality of life (QOL) impairment in individuals currently suffering from Graves’ ophthalmopathy (GO) and to determine the correlation of GO-specific QOL scores with disease severity and activity. Subjects and methods Seventy three GO-specific QOL surveys were prospectively analysed and compared wi
Arch. Endocrinol. Metab.. Publicado em: 16/02/2017
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7. Gene expression of estrogen receptor-alpha in orbital fibroblasts in Graves’ ophthalmopathy
Graves’ ophthalmopathy (GO) is one of the most severe clinical manifestations of Graves’ disease (GD), and its treatment might involve high-dose glucocorticoid therapy. The higher incidence of GO among females, and the reported association between polymorphisms of estrogen receptor (ER) and GD susceptibility have led us to question the role of estrogen a
Arch. Endocrinol. Metab.. Publicado em: 2015-06
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8. Detecção da neuropatia óptica distireoidiana pela quantificação dos músculos extra-oculares e da gordura orbitária na tomografia computadorizada / Predicting dysthyroid optic neuropathy using computed tomography quantitative analysis of extraocular muscles and orbital fat
OBJETIVO: avaliar a capacidade de índices de preenchimento muscular da órbita, calculados a partir de medidas na tomografia computadorizada de multidetectores, detectar a neuropatia óptica distireoidiana em pacientes com orbitopatia de Graves. MÉTODOS: noventa e três pacientes com diagnóstico de orbitopatia de Graves foram prospectivamente estudados. T
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/09/2012
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9. Avaliação da veia oftálmica superior por meio do Doppler colorido nas diferentes formas e estágios da orbitopatia de Graves / Evaluation of the superior ophthalmic vein by color Doppler in different forms and stages of Graves Orbitopathy
INTRODUÇÃO: A orbitopatia de Graves é uma doença autoimune cujas manifestações clínicas ocorrem por infiltração tecidual inflamatória. Apresenta estágio ativo inicial e estágio sequelar posteriormente, podendo se manifestar nas formas clínicas miogênica ou lipogênica. A inflamação da órbita pode gerar importante congestão, agravando manife
Publicado em: 2011
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10. Radioterapia para pacientes portadores de oftalmopatia de Graves: avaliação clínica e radiológica / Radiotherapy for Graves ophthalmopathy patients: clinical and radiological evaluations
Objetivo: Avaliar a melhora clínica e radiológica de pacientes com oftalmopatia de Graves, submetidos à radioterapia em órbitas concomitante ou não à corticoterapia. Métodos e materiais: Foram avaliados dezoito pacientes (36 órbitas) submetidos à radioterapia em órbitas com dose total de 10 Gy, fracionado em 1 Gy uma vez por semana durante 10 seman
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/09/2009
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11. Comparative evaluation of oculometric variables in graves' ophthalmopathy
OBJECTIVES: To estimate oculometric parameters of Graves' ophthalmopathy in comparison to healthy eyes using digital photography and digital image analysis. INTRODUCTION: Graves' ophthalmopathy is the main cause of eye proptosis. Because these protrusions cause clinically perceived distortions in orbital architecture, digital photographs can be used to detec
Clinics. Publicado em: 2009
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12. Perfil genetico de risco para doença de Graves e para a oftalmopatia de Graves em uma população brasileira / Genetic profile of risk to Graves disease and Graves ophthalmology in a Brazilian population
A Doença de Graves é um processo imunológico em que a combinação de fatores genéticos e ambientais é fundamental. Vários genes têm sido propostos como envolvidos no desenvolvimento da doença, particularmente os genes do sistema HLA e os polimorfismos do gene CTLA-4. Com relação à Oftalmopatia de Graves, além dos fatores genéticos, o tabagismo
Publicado em: 2009