Gnrh Analog
Mostrando 1-12 de 13 artigos, teses e dissertações.
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1. Challenges in monitoring GnRH analog treatment in central precocious puberty
ABSTRACT While the developed world is focusing on laying guidelines for selecting out cases of Asymptomatic primary hyperparathyroidism (PHPT) for surgical intervention and promoting minimal access surgery, the developing world is observing a change in disease spectrum from advanced symptomatic to lesser degree of symptomatic disease and not many with associ
Arch. Endocrinol. Metab.. Publicado em: 2020-04
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2. Clinical and Laboratory Parameters of Gonadotropin-Releasing Hormone Analog Treatment Effectiveness in Children with Precocious Puberty
OBJECTIVE: There are no doubts about the clinical benefits of treatment with GnRH analogs for patients diagnosed with central precocious puberty (CPP). However, laboratory monitoring of CPP is still a matter of considerable controversy in the literature. Therefore, the main objective of this study was to evaluate the cut-off values of stimulated LH that det
Clinics. Publicado em: 07/11/2019
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3. Pharmacological Treatment for Symptomatic Adenomyosis: A Systematic Review
Resumo Objetivo: Avaliar a eficácia de tratamento não cirúrgico para adenomiose. Fontes de dados: Uma pesquisa foi realizada por dois autores nas bases de dados Pubmed, Scopus, Scielo e na literatura cinzenta desde o início de cada base de dados até março de 2018, sem restrição de idioma. Seleção de estudos: Incluímos estudos prospectivos rando
Rev. Bras. Ginecol. Obstet.. Publicado em: 30/09/2019
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4. Central precocious puberty: revisiting the diagnosis and therapeutic management
ABSTRACT Clinical and laboratory diagnosis and treatment of central precocious puberty (CPP) remain challenging due to lack of standardization. The aim of this revision was to address the diagnostic and therapeutic features of CPP in Brazil based on relevant international literature and availability of the existing therapies in the country. The diagnosis of
Arch. Endocrinol. Metab.. Publicado em: 2016-04
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5. EIXO ECA2/ANG-(1-7)/MAS E SUA REGULAÇÃO NO PROCESSO DE OVULAÇÃO / ECA2/ANG-(1-7)/MAS AXIS AND ITS REGULATION DURING THE PROCESS OF OVULATION
The Renin-Angiotensin System (RAS) has been associated with various reproductive functions, including the ovulatory cascade. Unlike angiotensin II (AngII), the role of angiotensin-(1-7) [Ang-(1-7)] has not been characterized in the ovary of mono-ovulatory species. The objective of this study was to determine the Ang-(1-7) concentration in follicular fluid an
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/02/2011
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6. Utilização de um análogo do hormônio liberador de gonadotrofinas (Lecirelina) na indução e sincronização da ovulação em porcas. / Utilization of a gonadotropin-releasing hormone analogue (lecirelin) on induction and synchronization of ovulation in sows
O análogo de GnRH, Lecirelina (Gestran Plus®; ARSA S.R.L., Buenos Aires, Argentina), foi testado para habilidade de induzir e sincronizar a ovulação de porcas. As fêmeas foram uniformemente distribuídas após o desmame, em dois grupos de 56 fêmeas de acordo com a ordem de parto (OP) (2-6), intervalo desmame-estro (IDE) e escore corporal visual (ECV).
Publicado em: 2010
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7. Pituitary gonadotropin-releasing hormone receptors. Effects of castration, steroid replacement, and the role of gonadotropin-releasing hormone in modulating receptors in the rat.
To study the role of gonadotropin-releasing hormone (GnRH) receptors in the regulation of gonadotropin secretion, we used D-125I-alanine6 des glycyl10 GnRH ethylamide (D-125I-Ala analog), a nondegradable, superagonist GnRH analog to assess GnRH receptors on rat pituitary membranes. Receptor affinity in intact adult rats was 5.0 X 10(9) M-1 and was unchanged
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8. Expression of gonadotropin-releasing hormone receptors and autocrine regulation of neuropeptide release in immortalized hypothalamic neurons.
The hypothalamic control of gonadotropin secretion is mediated by episodic basal secretion and midcycle ovulatory surges of gonadotropin-releasing hormone (GnRH), which interacts with specific plasma membrane receptors in pituitary gonadotrophs. Similar GnRH receptors and their mRNA transcripts were found to be expressed in immortalized hypothalamic neurons,
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9. Puberty in monkeys is triggered by chemical stimulation of the hypothalamus.
Gonadal quiescence prior to puberty in primates results from a diminished secretion of the pituitary gonadotropic hormones, follicle-stimulating hormone and luteinizing hormone, which, in turn, is occasioned by an interruption of pulsatile release of gonadotropin-releasing hormone (GnRH) from the hypothalamus during this phase of development. A discharge of
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10. Covalent linking of photoreactive gonadotropin-releasing hormone to gonadotropes produces a prolonged signal.
A bioactive, photoreactive derivative of gonadotropin-releasing hormone (GnRH; gonadoliberin), [azidobenzoyl-D-Lys6]GnRH, was shown to bind covalently to dispersed pituitary cells after irradiation. Approximately 7% of the total cell-associated radioactivity was covalently bound to the receptors. Photolysis of cultured pituitary cells in the presence of the
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11. Mast cells with gonadotropin-releasing hormone-like immunoreactivity in the brain of doves.
Using an antiserum (LR-1) raised against mammalian gonadotropin-releasing hormone (GnRH), we previously identified a nonneuronal cell that was more numerous in the medial habenula (MH) of courting ring doves than in individuals housed in visual isolation. The current studies suggest that they are mast cells. Both acidic toluidine blue and toluidine blue diss
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12. Simultaneous measurement of hormone release and secretagogue binding by individual pituitary cells.
The quantitative relationship between receptor binding and hormone secretion at the single-cell level was investigated in the present study by combining a reverse hemolytic plaque assay for measurement of luteinizing hormone (LH) secretion from individual pituitary cells with an autoradiographic assay of 125I-labeled gonadotropin-releasing hormone (GnRH) ago