Gly Leu Rich Peptides
Mostrando 1-6 de 6 artigos, teses e dissertações.
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1. Leptoglicina: um novo Peptídeo Antimicrobiano rico em Gly-Leu isolado da secreção da pele da rã sul americana Leptodactylus Pentadactylus (Leptodactylidae) / Leptoglicina: a new antimicrobial peptide rich in Gly-Leu isolated from skin secretions of the South American frog Leptodactylus Pentadactylus (Leptodactylidae)
Peptídeos antimicrobianos são componentes do sistema imune de vertebrados e invertebrados e são a primeira linha defesa contra a invasão de microrganismos. Nesse estudo, descrevemos o isolamento, caracterização biológica e seqüência de aminoácidos de um novo peptídeo antimicrobiano neutro rico em Gly-Leu isolado da secreção da pele de L. pentadc
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 07/01/2008
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2. Differential processing of prodynorphin and proenkephalin in specific regions of the rat brain.
Prodynorphin-derived peptides [dynorphin A (Dyn A)-(1-17), Dyn A-(1-8), Dyn B, alpha-neo-endorphin, and beta-neo-endorphin] and proenkephalin-derived peptides [[Leu]enkephalin [( Leu]Enk) and [Met]enkephalin-Arg6-Gly7-Leu8 [( Met]Enk-Arg-Gly-Leu]) in selected brain areas of the rat were measured by specific radioimmunoassays. We report here that different re
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3. Role of membrane lipids in peptide hormone function: binding of enkephalins to micelles.
In the course of their biological function, peptide hormones must be transferred from an aqueous phase to the lipid-rich environment of their membrane-bound receptor proteins. We have investigated the possible influence of phospholipids in this process, using 360-MHz 1H and 90-MHz 13C NMR spectroscopy to examine the association of the opioid peptides [Met]-
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4. Purification, primary structure, and biological activity of guinea pig neutrophil cationic peptides.
The guinea pig neutrophil cationic peptides GNCP-1 and GNCP-2 were purified from a granule-rich subcellular fraction of peritoneal exudate neutrophils by acid-gel electrophoresis and reversed-phase high-performance liquid chromatography. Both peptides not only released histamine from rat mast cells to the same extent but also were equally active against Stap
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5. Identity of a second type of allatostatin from cockroach brains: an octadecapeptide amide with a tyrosine-rich address sequence.
An octadecapeptide that inhibits juvenile hormone synthesis has been isolated by HPLC from brain-retrocerebral complexes of the cockroach Diploptera punctata. The primary structure of this allatostatin has been elucidated by tandem mass spectrometry: Ala-Tyr-Ser-Tyr-Val-Ser-Glu-Tyr-Lys-Arg-Leu-Pro-Val-Tyr-Asn-Phe-Gly-Leu- NH2 (ASB2). The amidated three-resid
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6. Inhibition of platelet function with synthetic peptides designed to be high-affinity antagonists of fibrinogen binding to platelets.
We have constructed synthetic peptides modeled on the sequences of (i) Arg-Gly-Asp, present in fibrinogen, fibronectin, and von Willebrand factor, and of (ii) the fibrinogen gamma chain (gamma 400-411) His-His-Leu-Gly-Gly-Ala-Lys-Gln-Ala-Gly-Asp-Val. The concentration of each peptide that inhibits 50% of 125I-labeled fibrinogen binding to thrombin-stimulated