Glutathione Stransferase
Mostrando 1-12 de 767 artigos, teses e dissertações.
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1. Phytogenic as feed additive for suckling dairy calves’ has a beneficial effect on animal health and performance
Abstract: The aim of this study was to evaluate whether the use phytogenic as feed additive of Holstein calves could exert beneficial effects on animal health and performance. Thirty newborn calves were randomly divided into two groups (control and treated), and the treated consisted of 10 g of the phytogenic product diluted in milk once a day for 30 days. B
An. Acad. Bras. Ciênc.. Publicado em: 28/11/2019
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2. Zingiber officinale formulation reduces hepatic injury and weight gain in rats fed an unhealthy diet
Abstract: This study investigated the ability of formulation containing Zingiber officinale (ginger) to reverse health changes promoted by unhealthy diet in Wistar rats. Five compounds from the gingerol family and three from the shogaol family were identified in the chromatographic analyzes of the extract. The animals were fed a combination of unhealthy food
An. Acad. Bras. Ciênc.. Publicado em: 11/11/2019
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3. Water acidification causes death of marine ornamental fish (Perciformes: Pomacentridae) during transport: contributing to the conservation of wild populations
ABSTRACT Pomacentridae is a common family in the aquarium fish trade. Most species are harvested from nature. Here we evaluate the following water parameters in the pomacentrid sergeant major, Abudefduf saxatilis (Linnaeus, 1758), to assess their stress level during a 24, 48, and 72 hours transport: dissolved oxygen (DO), total ammonia, and pH. In addition,
Zoologia (Curitiba). Publicado em: 06/06/2019
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4. Análise comparativa do polimorfismo genético da glutationa transferase, do Helicobacter pylori e do vírus Epstein-Barr entre a área do tumor e as margens de ressecção proximal e distal do câncer gástrico.
RESUMO Objetivo: comparar o polimorfismo dos genes Glutationa S-transferase teta 1 (GSTT1) e Glutationa S-transferase mu 1 (GSTM1) da área do tumor com as margens proximal e distal de espécimes de estômago ressecados de pacientes com câncer gástrico, e investigar a presença do DNA do vírus Epstein-Barr (EBV) e Helicobacter pylori. Métodos: coletamo
Rev. Col. Bras. Cir.. Publicado em: 31/01/2019
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5. The impacts of Elaeagnus umbellata Thunb. leaf and fruit aqueous extracts on mice hepatic, extrahepatic antioxidant and drug metabolizing enzymes related structures
ABSTRACT In this work, the potential chemopreventive activities of Elaeagnus umbellata fruit aqueous (EUFA) and leaf aqueous (EULA) extracts focusing on the modulatory influence of xenobiotic metabolizing enzymes (XMEs), antioxidant enzymes, glucose-6-phosphate dehydrogenase (G6PD), 6-phosphogluconate dehydrogenase (6PGD), lactate dehydrogenase (LDH) activit
Braz. J. Pharm. Sci.. Publicado em: 01/02/2018
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6. A study of the association of glutathione S-transferase M1/T1 polymorphisms with susceptibility to vitiligo in Egyptian patients
Abstract: Background: The association of glutathione S-transferases M1/T1 (GSTM1/T1) null polymorphisms with vitiligo was proposed in several studies including two Egyptian studies with contradictory results. Objective: The aim here was to assess the association between GSTM1/T1 null polymorphisms and the susceptibility to vitiligo in a larger sample of Eg
An. Bras. Dermatol.. Publicado em: 2018-02
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7. The Role of the Conformational Dynamics of Glutathione S-Transferase Epsilon Class on Insecticide Resistance in Anopheles gambiae
Glutathione S-transferases (GSTs) are enzymes capable of metabolizing cytotoxic compounds. The enzyme AgGSTE2, member of epsilon class GSTs (GSTE), is the most important GST conferring resistance to dichloro-diphenyl-trichloroethane (DDT) in Anopheles gambiae. We have investigated the conformational dynamics of three GSTE variants (GSTE2, GSTE2-I114T/F120L,
J. Braz. Chem. Soc.. Publicado em: 2016-09
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8. Dideoxy single allele-specific PCR - DSASP new method to discrimination allelic
Gastric cancer (GC) is a multifactorial disease with a high mortality rate in Brazil and worldwide. This work aimed to evaluate single nucleotide polymorphisms (SNP) rs1695, in the Glutathione S-Transferase Pi (GSTP1) gene in GC samples by comparative analysis Specific PCR - ASP and Dideoxy Single Allele-Specific PCR - DSASP methods. The DSASP is the propose
Braz. arch. biol. technol.. Publicado em: 2015-06
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9. Characterization of an alcoholic hepatic steatosis model induced by ethanol and high-fat diet in rats
Alcoholic liver disease is characterized by a wide spectrum of liver damage, which increases when ethanol is associated with high-fat diets (HFD). This work aimed to establish a model of alcoholic hepatic steatosis (AHS) by using a combination of 10% ethanol and sunflower seeds as the source of HFD. Male rats received water or 10% ethanol and regular chow di
Braz. arch. biol. technol.. Publicado em: 06/03/2015
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10. Combined administration of silymarin and vitamin C stalls acetaminophen-mediated hepatic oxidative insults in Wistar rats
Oxidative insult by free radicals has been implicated in drug-induced hepatic damage and this has resulted in frequent episodes of liver disorders. Therapeutic efficacy of antioxidants may provide a possible solution to this menace. This study was carried out to investigate the effect of combined administration of silymarin and vitamin C in rescuing acetamin
Rev. bras. farmacogn.. Publicado em: 2015-02
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11. Human glutathione S-transferase polymorphisms associated with prostate cancer in the Brazilian population
Objective To evaluate the influence of polymorphisms in GSTA1, GSTM1, GSTT1, and GSTP1 in the risk of developing Prostate Cancer (PCa) in a population of Rio de Janeiro and compare the distribution of allele and genotype frequencies of the polymorphisms analyzed in the present study population with other regions in the country and different ethnic groups.
Int. braz j urol.. Publicado em: 2014-08
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12. Molecular characteristics, recombinant expression and activity detection of OsGSTL1 from rice
The mRNA of OsGSTL1 was detected in the roots and leaves of rice plants at seedling and tillering stages, and their roots, leaves and panicles at the heading stage. The full-length open reading frame of OsGSTL1 cDNA was 732 bp and encoded a putative polypeptide of 243 amino acids with a calculated molecular mass of 27.30 kDa and a theoretical pI of 5.50. The
Braz. arch. biol. technol.. Publicado em: 2014-02