Glutaric Acid
Mostrando 1-12 de 28 artigos, teses e dissertações.
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1. A INFLUÊNCIA DO PROCESSO INFLAMATÓRIO NAS CONVULSÕES E NO DÉFICIT COGNITIVO INDUZIDOS PELO ÁCIDO GLUTÁRICO EM RATOS JOVENS / THE INFLUENCE OF THE INFLAMMATORY PROCESS IN SEIZURES AND COGNITIVE DEFICIT INDUCED BY GLUTARIC ACID IN YOUNG RATS
A acidemia glutárica tipo I (GA-I) é um erro inato do metabolismo (EIM) caracterizada bioquimicamente pelo acúmulo principal de ácido glutárico (GA) e patologicamente por uma característica degeneração estriatal. As manifestações clínicas são predominantemente neurológicas, e desenvolvem-se principalmente na infância (até os 5 anos de idade).
Publicado em: 2011
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2. Inhibition of in vitro CO2 production and lipid synthesis by 2-hydroxybutyric acid in rat brain
2-Hydroxybutyric acid appears at high concentrations in situations related to deficient energy metabolism (e.g., birth asphyxia) and also in inherited metabolic diseases affecting the central nervous system during neonatal development, such as "cerebral" lactic acidosis, glutaric aciduria type II, dihydrolipoyl dehydrogenase (E3) deficiency, and propionic ac
Publicado em: 2010
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3. EFEITO NEUROPROTETOR DA CREATINA E AVALIAÇÃO DOS PARÂMETROS CINÉTICOS DA CAPTAÇÃO DE GLUTAMATO INDUZIDOS PELO ÁCIDO GLUTÁRICO NO ESTRIADO DE RATOS / NEUROPROTECTIVE EFFECT OF CREATINE AND EVALUATION OF KINETIC PARAMETERS OF GLUTAMATE UPTAKE INDUCED BY GLUTARIC ACID FROM STRIATUM THE RATS
A acidemia glutárica tipo I (GA-I) é um erro inato do metabolismo (EIM) caracterizada bioquimicamente pelo acúmulo principal de ácido glutárico (GA) e ácido 3-hidroxiglutárico (3-OH-GA), e patologicamente por uma característica degeneração estriatal. Devido à escassez de medidas terapêuticas efetivas para essa acidemia, vários estudos têm inves
Publicado em: 2008
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4. Inhibition of in vitro CO2 production and lipid synthesis by 2-hydroxybutyric acid in rat brain
2-Hydroxybutyric acid appears at high concentrations in situations related to deficient energy metabolism (e.g., birth asphyxia) and also in inherited metabolic diseases affecting the central nervous system during neonatal development, such as "cerebral" lactic acidosis, glutaric aciduria type II, dihydrolipoyl dehydrogenase (E3) deficiency, and propionic ac
Brazilian Journal of Medical and Biological Research. Publicado em: 2001-05
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5. Transformation of 1-Menthene by a Cladosporium: Accumulation of β-Isopropyl Glutaric Acid in the Growth Medium
An organism isolated from soil samples collected near a terpene plant grew in the presence of 1-menthene, with no other major source of carbon and energy. The organism was tentatively identified as a member of the genus Cladosporium. When this organism was grown in the presence of 1-menthene, with no other major source of carbon, substantial quantities of β
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6. Production of Glutaric Acid: a Useful Criterion for Differentiating Pseudomonas diminuta from Pseudomonas vesiculare
A gas-liquid chromatographic procedure was used to determine short-chain acids produced by Pseudomonas diminuta and P. vesiculare after growth on Trypticase soy agar. Each of nine strains of P. diminuta produced glutaric acid, whereas none of the strains of P. vesiculare produced this acid.
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7. Inhibition of Glucose-Induced Release of Insulin by Aldose Reductase Inhibitors
Aldose reductase (alditol: NADP oxidoreductase, EC 1.1.1.21) is the enzyme responsible for the conversion of glucose to its sugar alcohol, sorbitol. In this study, aldose reductase and a closely related enzyme, L-hexonate dehydrogenase (L-gulonate: NADP oxidoreductase, EC 1.1.1.19), were purified from rat pancreas. Glutaric acid, 2,4-dimethyl glutaric acid,
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8. Inactivation of rhinovirus on human fingers by virucidal activity of glutaric acid.
Hand lotion containing 2% glutaric acid was significantly more effective than placebo in inactivating rhinovirus serotype 2 on the fingers of human volunteers. It may be possible to develop safe, cosmetically acceptable hand lotions which have durable virucidal activity and can interrupt the hand-to-hand transmission of rhinovirus colds.
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9. Virucidal activity of glutaric acid and evidence for dual mechanism of action.
Rhinoviruses as a group are notably sensitive to inactivation in solutions with a pH of less than 5.3. Glutaric acid appears to possess virucidal activity in addition to the aciduant effect against rhinoviruses. A model system in which rhinovirus type 14 was incubated in the presence of glutaric acid (GA) (pH 4.0) at 0 degrees C was devised to separate intri
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10. Expression of a Pseudomonas putida Aminotransferase Involved in Lysine Catabolism Is Induced in the Rhizosphere
Using a transposon carrying a promoterless lux operon to generate transcriptional fusions by insertional mutagenesis, we have identified a Pseudomonas putida gene with increased expression in the presence of corn root exudates. Expression of the transcriptional fusion, induced by the amino acid lysine, was detected in P. putida in the rhizosphere of plants a
American Society for Microbiology.
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11. Short-Chain Acids of Pseudomonas Species Encountered in Clinical Specimens
The short-chain acids of 36 strains of Pseudomonas grown on Trypticase soy agar were determined by gas-liquid chromatography. Distinct acid profiles were observed for each of the eight species tested. Propionic, isobutyric, and isovaleric acids were the principal acids detected in media extracts of P. maltophilia, P. cepacia, P. pseudoalcaligenes, P. diminut
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12. Lysine catabolism in Rhizoctonia leguminicola and related fungi.
The catabolism of lysine was studied in several yeasts and fungi. Results with cell-free extracts of Rhizoctonia leguminicola support a proposed pathway involving (D- and L-) EPSILON-N-acetyllysine, alpha-keto-epsilon-acetamidohexanoic acid, delta-acetamidovaleric acid, and delta-aminovaleric acid in the conversion of L-lysine to shortchain organic acids. La