Glutamatergic System
Mostrando 13-24 de 63 artigos, teses e dissertações.
-
13. Importância da região AV3V e de mecanismos colinérgicos e angiotensinérgicos centrais para os efeitos cardiovasculares produzidos pela ativação da área rostroventrolateral do bulbo
Cardiovascular responses are integrated at different levels of the central nervous system (CNS). In the brainstem, there are different areas related to the cardiovascular control such as the rostral ventrolateral medulla (RVLM) that activates sympathetic pre-ganglionic neurons in the spinal cord (IML) inducing pressor response. Like glutamatergic activation,
Publicado em: 2008
-
14. Estudo da neurotransmissão do quimiorreflexo e do barorreflexo na área A5 de ratos não anestesiados
The circulatory system is essential for the maintenance of body homeostasis. Neural regulation of the cardiovascular system involves the activation of several groups of peripheral sensors that generates the information to central nervous system, with consequent modulation of the autonomic nervous system. Among the peripheral sensors the arterial baroreceptor
Publicado em: 2007
-
15. MODULATION OF GLUTAMATERGIC SYSTEM IN PLATELETS: EFFECT OF HEAVY METALS AND ORGANOCHALCOGENS / MODULAÇÃO DO SISTEMA GLUTAMATÉRGICO EM PLAQUETAS: EFEITO DE METAIS PESADOS E ORGANOCALCOGÊNIOS
Recentes pesquisas têm sido desenvolvidas para caracterizar biomarcadores em tecidos periféricos que possam ser utilizados em casos de dano, disfunção ou interações envolvendo alvos de agentes tóxicos. As plaquetas têm sido amplamente sugeridas como um excelente modelo do aparato sináptico e, ainda tem sido demonstrado que estas células acumulam gl
Publicado em: 2007
-
16. "Efeito modulatório da nicotina sobre a neurotransmissão em núcleos encefálicos responsáveis pelo controle cardiovascular em ratos geneticamente hipertensos e normotensos" / "Nicotine modulatory effects on neurotransmiter systems in the cardiovascular brain areas of spontaneously hypertensive and normotensive rats"
Nicotine is one of the most important agents for cardiovascular diseases in tobacco smoking. This alkaloid acts in the blood stream, but it also crosses the blood-brain-barrier and participate in the regulation of pivotal neurotransmitter systems for the blood pressure control and, eventually, for hypertension development. In this context, nicotine abuse cou
Publicado em: 2006
-
17. NITRIC OXIDE MODULATES THE IMPROVEMENT OF THE MEMORY INDUCED BY SPERMIDINE IN RAT / ÓXIDO NÍTRICO MODULA A MELHORA DA MEMÓRIA INDUZIDA POR ESPERMIDINA EM RATOS
The endogenous poliaminas, putrescine, spermidina and spermine are aliphatics amines that are present in high concentrations in the central nervous system (SNC). The action of the poliamines involves the modulation of several ionic channels, including the subtype of glutamatergic N-methyl-D-aspartate receptor (NMDA). The processes mediated by NMDA receptor i
Publicado em: 2006
-
18. Efeitos do tratamento neonatal com inibidor Seletivo da recaptaÃÃo de serotonina sobre a Atividade osteoblÃstica e o crescimento de fÃmures de ratos
The interaction evidences are growing between the nervous system and the bone metabolism. Recent studies evidence glutamatergic, dopaminergic and serotoninergic receptors in the bone cells. However it is not still well documented the paper of the serotonina in the bone. In the present study, we investigated the role of the serotonin on the growth and develop
Publicado em: 2006
-
19. 1,2 AND 1,4-DICARBOXYLIC COMPOUNDS ACTUATE ON THE GLUTAMATERGIC SYSTEM AND THE BEHAVIOR OF RATS AND MICE / COMPOSTOS 1,2 E 1,4-DICARBOXÍLICOS ATUAM SOBRE O SISTEMA GLUTAMATÉRGICO E O COMPORTAMENTO DE RATOS E CAMUNDONGOS
Glutamatergic receptors are targets for many L-glutamate structure analogues, which cause neurotoxicity. This study investigated the actions of two dicarboxylic compounds, the first had cyclic framework and rigid structure, and the other had an acyclic framework and flexible structure, on the glutamatergic neurotransmission, oxidative damage and behavior in
Publicado em: 2005
-
20. EFEITO DA ADMINISTRAÇÃO AGUDA DE CREATINA SOBRE A MEMÓRIA EM RATOS / EFFECT OF THE SYSTEMIC INJECTION OF CREATINE ON THE MEMORY OF RATS
Glucose is the most important energy substrate for the central nervous system. Besides its energetic function, glucose facilitates memory in experimental animals, an effect that has been related to its energy functions. Other important cerebral energy substrate is creatine, which is endogenously synthesized and converted to phosphocreatine, an immediate and
Publicado em: 2005
-
21. Importância da região AV3V para as respostas pressoras produzidas pela ativação de áreas bulbares.
Cardiovascular responses are integrated at different levels of the central nervous system (CNS). Particularly the hypothalamus and brainstem areas are involved in the control of autonomic responses and among them the cardiovascular responses. Different areas in the brainstem, like the nucleus tract solitarii (NTS), the rostroventrolateral medulla (RVLM), cau
Publicado em: 2005
-
22. Glutamatergic neurotransmission modulates hypoxia-induced hyperventilation but not anapyrexia
The interaction between pulmonary ventilation (V E) and body temperature (Tb) is essential for O2 delivery to match metabolic rate under varying states of metabolic demand. Hypoxia causes hyperventilation and anapyrexia (a regulated drop in Tb), but the neurotransmitters responsible for this interaction are not well known. Since L-glutamate is released centr
Brazilian Journal of Medical and Biological Research. Publicado em: 2004-10
-
23. Molecular cloning and functional characterization of human vesicular glutamate transporter 3
Glutamate is the major excitatory neurotransmitter in the mammalian CNS. It is loaded into synaptic vesicles by a proton gradient-dependent uptake system and is released by exocytosis upon stimulation. Recently, two mammalian isoforms of a vesicular glutamate transporter, VGLUT1 and VGLUT2, have been identified, the expression of which enables quantal releas
Oxford University Press.
-
24. Neurotoxicity of Clostridium perfringens Epsilon-Toxin for the Rat Hippocampus via the Glutamatergic System
The neurotoxicity of epsilon-toxin, one of the major lethal toxins produced by Clostridium perfringens type B, was studied by histological examination of the rat brain. When the toxin was injected intravenously at a lethal dose (100 ng/kg), neuronal damage was observed in many areas of the brain. Injection of the toxin at a sublethal dose (50 ng/kg) caused n
American Society for Microbiology.