Glucocorticoid Levels
Mostrando 1-12 de 304 artigos, teses e dissertações.
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1. Central adrenal insufficiency: who, when, and how? From the evidence to the controversies – an exploratory review
ABSTRACT Central adrenal insufficiency (CAI) is a life-threatening disorder. This occurs when ACTH production is insufficient, leading to low cortisol levels. Since corticosteroids are crucial to many metabolic responses under organic stress and inflammatory conditions, CAI recognition and prompt treatment are vital. However, the diagnosis of CAI is challeng
Archives of Endocrinology and Metabolism. Publicado em: 2022
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2. Guidelines of the Brazilian Society of Rheumatology for the treatment of systemic autoimmune myopathies
Abstract Background: Recommendations of the Myopathy Committee of the Brazilian Society of Rheumatology for the management and therapy of systemic autoimmune myopathies (SAM). Main body: The review of the literature was done in the search for the Medline (PubMed), Embase and Cochrane databases including studies published until June 2018. The Prisma was use
Adv. rheumatol.. Publicado em: 29/07/2019
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3. Characterization of scrotal involvement in children and adolescents with IgA vasculitis
Abstract Objective: To characterize scrotal involvement in children and adolescents with IgA vasculitis. Methods: A cross-sectional retrospective study included 296 IgA vasculitis (EULAR/PRINTO/PRES criteria) patients, 150/296 (51%) were males and assessed by demographic/clinical/laboratory and treatments. Scrotal involvement was defined by the presence of
Adv. rheumatol.. Publicado em: 29/07/2019
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4. Frequency and clinical relevance of anti-Mi-2 autoantibody in adult Brazilian patients with dermatomyositis
Abstract Background: To analyze the frequency and clinical relevance of anti-Mi-2 autoantibody in a representative sample of patients with dermatomyositis. Methods: This longitudinal inception cohort study, from 2001 to 2017, included 87 definite adult dermatomyositis. Anti-Mi-2 analysis was performed using a commercial kit. Results: Seventeen patients (1
Adv. rheumatol.. Publicado em: 29/07/2019
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5. Impacts of food-based enrichment on behaviour and physiology of male greater rheas (Rhea Americana, Rheidae, Aves)
Abstract Distress can be defined as a biological response of an individual to long-term threats to its homeostasis and it should be avoided from an animal welfare perspective. High levels of stress hormones and the expression of abnormal behaviours are responses normally observed in distressed animals. Captive environments can provoke distress, especially wh
Pap. Avulsos Zool.. Publicado em: 20/05/2019
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6. Association of glucocorticoid receptor polymorphisms with clinical and metabolic profiles in polycystic ovary syndrome
OBJECTIVES: We aimed to investigate whether glucocorticoid receptor gene polymorphisms are associated with clinical and metabolic profiles in patients with polycystic ovary syndrome. Polycystic ovary syndrome is a complex endocrine disease that affects 5-8% of women and may be associated with metabolic syndrome, which is a risk factor for cardiovascular dis
Clinics. Publicado em: 2014-03
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7. Modulatory effect of BclI GR gene polymorphisms on the obesity phenotype in Brazilian patients with Cushing's disease
OBJECTIVES: Patients with Cushing's disease exhibit wide phenotypic variability in the severity of obesity, diabetes and hypertension. In the general population, several glucocorticoid receptor genes (NR3C1) and HSD11B1 polymorphisms are associated with altered glucocorticoid sensitivity and/or metabolism, resulting in an increased or reduced risk of an adv
Clinics. Publicado em: 2013-05
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8. Chloroquine diphosphate: a risk factor for herpes zoster in patients with dermatomyositis/polymyositis
OBJECTIVES: Herpes zoster has been widely described in the context of different systemic autoimmune diseases but not dermatomyositis/polymyositis. Therefore, we analyzed the prevalence, risk factors and herpes zoster outcomes in this population. METHOD: A retrospective cohort study of herpes zoster infections in dermatomyositis/polymyositis patients was p
Clinics. Publicado em: 2013-05
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9. Mineralocorticoid replacement during infancy for salt wasting congenital adrenal hyperplasia due to 21-hydroxylase deficiency
OBJECTIVE: The protocols for glucocorticoid replacement in children with salt wasting 21-hydroxylase deficiency are well established; however, the current recommendation for mineralocorticoid replacement is general and suggests individualized dose adjustments. This study aims to retrospectively review the 9-∝-fludrocortisone dose regimen in salt wasting 21
Clinics. Publicado em: 2013
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10. Estresse precoce e alterações do eixo hipotálamo-pituitária-adrenal (HPA) na depressão. / Early Life Stress and alterations of the Hypothalamic-Pituitary-Adrenal (HPA) axis in depression.
Introduction: Several studies suggest that stress in early stages of development can induce persistent changes in the ability of the Hypothalamic-Pituitary-Adrenal (HPA) axis to respond to stress in adulthood. The imbalance of cortisol has been identified as a biological correlate of depressive disorders. These abnormalities seem to be related to changes in
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/03/2012
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11. Neural regulation of the stress response: glucocorticoid feedback mechanisms
The mammalian stress response is an integrated physiological and psychological reaction to real or perceived adversity. Glucocorticoids are an important component of this response, acting to redistribute energy resources to both optimize survival in the face of challenge and to restore homeostasis after the immediate challenge has subsided. Release of glucoc
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-04
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12. Pharmacogenetics of glucocorticoid replacement could optimize the treatment of congenital adrenal hyperplasia due to 21-hydroxylase deficiency
INTRODUCTION: 21-hydroxylase deficiency is an autosomal recessive disorder that causes glucocorticoid deficiency and increased androgen production. Treatment is based on glucocorticoid replacement; however, interindividual variability in the glucocorticoid dose required to achieve adequate hormonal control has been observed. OBJECTIVE: The present study aime
Clinics. Publicado em: 2011