Glucagon Like Peptide 1
Mostrando 1-12 de 88 artigos, teses e dissertações.
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1. Maintenance of plasma glucose variability after an acute session of aerobic exercise despite changes in insulin and glucagon-like peptide-1 levels in type 2 diabetes
ABSTRACT Objective: The present study aimed to evaluate glucose variability and hormonal responses during and after an aerobic exercise session performed after breakfast in type 2 diabetes patients treated with metformin. Materials and methods: In this quasi-experimental study individuals underwent clinical and laboratory evaluations and maximal exercise t
Archives of Endocrinology and Metabolism. Publicado em: 2022
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2. The effects of macronutrients composition on hormones and substrates during a meal tolerance test in drug-naive and sitagliptin-treated individuals with type 2 diabetes: a randomized crossover study
ABSTRACT Objectives: To evaluate the effect of sitagliptin treatment in early type 2 diabetes mellitus (T2DM) and the impact of different macronutrient compositions on hormones and substrates during meal tolerance tests (MTT). Materials and methods: Half of the drug-naive patients with T2DM were randomly assigned for treatment with 100 mg of sitagliptin, q
Archives of Endocrinology and Metabolism. Publicado em: 2022
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3. Binge eating disorder, frequency of depression, and systemic inflammatory state in individuals with obesity – A cross sectional study
ABSTRACT Objective: Binge eating disorder (BED) is the most prevalent eating disorder in individuals with obesity. Its association with factors that control hunger and satiety has not yet been elucidated. We evaluated whether levels of inflammatory markers, frequency of psychiatric comorbidities, and appetite-related hormones levels differ between individua
Archives of Endocrinology and Metabolism. Publicado em: 2022
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4. Obesity care: more urgent than ever
ABSTRACT Deleterious effects of free fatty acids, FFAs, on insulin sensitivity are observed in vivo studies in humans. Mechanisms include impaired insulin signaling, oxidative stress, inflammation, and mitochondrial dysfunction, but the effects on insulin secretion are less well known. Our aim was to review the relationship of increased FFAs with insulin res
Arch. Endocrinol. Metab.. Publicado em: 2021-02
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5. Effect of free fatty acids on insulin secretion, insulin sensitivity and incretin effect – a narrative review
ABSTRACT Deleterious effects of free fatty acids, FFAs, on insulin sensitivity are observed in vivo studies in humans. Mechanisms include impaired insulin signaling, oxidative stress, inflammation, and mitochondrial dysfunction, but the effects on insulin secretion are less well known. Our aim was to review the relationship of increased FFAs with insulin res
Arch. Endocrinol. Metab.. Publicado em: 2021-02
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6. Use of flash glucose-sensing technology in patients with type 2 diabetes treated with liraglutide combined with CSII: a pilot study
Glycemic variability (GV) may be linked to the development of diabetic complications by inducing inflammation, oxidative stress, and endothelial dysfunction. Flash glucose monitoring (FGM) provides a novel method of continuously monitoring interstitial glucose levels for up to 14 days. This study randomly assigned poorly controlled type 2 diabetes mellitus p
Braz J Med Biol Res. Publicado em: 2020-01
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7. Association Between Exercise and Treatment with Liraglutide in Obese Rats by Cafeteria Diet
Abstract The objective of this study was to evaluate the effect of liraglutide, an analog of glucagon-like peptide-1 (GLP-1) in association with physical exercise, on the metabolic and biochemical parameters of rats induced to obesity with a cafeteria diet. Male Wistar rats, aged 21 days, were randomly divided into: Controls (CON) receiving standard feed and
Braz. arch. biol. technol.. Publicado em: 24/10/2019
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8. Exenatide ameliorates hepatic steatosis and attenuates fat mass and FTO gene expression through PI3K signaling pathway in nonalcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) is a common disease associated with metabolic syndrome and can lead to life-threatening complications like hepatic carcinoma and cirrhosis. Exenatide, a glucagon-like peptide-1 (GLP-1) receptor agonist antidiabetic drug, has the capacity to overcome insulin resistance and attenuate hepatic steatosis but the specific
Braz J Med Biol Res. Publicado em: 14/06/2018
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9. Glucagon-like peptide 1 improves insulin resistance in vitro through anti-inflammation of macrophages
Glucagon-like peptide 1 (GLP-1), a kind of gut hormone, is used in the treatment of type 2 diabetes (T2D). Emerging evidence indicates that GLP-1 has anti-inflammatory activity. Chronic inflammation in the adipose tissue of obese individuals is a cause of insulin resistance and T2D. We hypothesized that GLP-1 analogue therapy in patients with T2D could suppr
Braz J Med Biol Res. Publicado em: 21/11/2016
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10. A TEORIA DO DIAMANTE AZUL DE TENDÊNCIA DO ESTUDO DA METANÁLISE (TDATEM) - Diamante Azul Aplicado Na Isquemia Reperfusão Cardíaca.
A B S T R A C TThe restoration of blood flow of a vessel, after a period of obstruction and ischemia leads to functional and structural changes, which are titrated reperfusion injury. There is no drug therapy, which may be considered the "gold standard" for these cases. Objective: Present a systematic review by Theory of Blue Diamond Trend Study of Meta-Anal
Publicado em: 03/07/2014
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11. Ação do inibidor da enzima dipeptidil peptidase 4 sobre o pré-condicionamento isquêmico em pacientes portadores de diabetes mellitus tipo 2 e doença arterial coronariana estável / Effect of dipeptidyl peptidase-4 enzyme inhibitor on ischemic preconditioning in patients with type 2 diabetes and symptomatic coronary artery disease
Ischemic preconditioning (IPC) refers to the phenomenon in which short periods of myocardial ischemia and reperfusion promote resistance to a subsequent prolonged ischemic insult. Some hypoglycemic drugs, such as glibenclamide and repaglinide, are able to inhibit this protective phenomenon probably by its effects as blockers of adenosine triphosphate-depende
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 19/10/2012
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12. Eficácia da sitagliptina no controle glicêmico e na função cardiovascular de pacientes portadores de diabetes mellitus tipo 2 tratados com metformina e glibenclamida / Efficacy of sitagliptin on glycemic control and cardiovascular function in patients with type 2 diabetes mellitus treated with metformin and glibenclamide
No tratamento do diabetes mellitus tipo 2, busca-se a otimização do controle glicêmico para evitar as complicações da doença. Quando a combinação mais utilizada (sulfoniluréia e biguanida) falha em manter o controle glicêmico, um terceiro agente é associado, podendo ser a insulina ou outro hipoglicemiante oral. O objetivo deste estudo foi comparar
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 11/07/2012