Gentamicin Sulfate
Mostrando 1-12 de 46 artigos, teses e dissertações.
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1. Síntese, caracterização e aplicação biológica de hidroxiapatita: em presença de gelatina e associada a sulfato de gentamicina
A utilização de biomateriais remonta à antiguidade e recentemente as biocerâmicas têm sido fortemente investigadas como material para implantes ósseos. Dentre os diferentes biomateriais a hidroxiapatita (HA) possui grande importância por ser um dos compostos que forma a fase mineral óssea. Assim, a HA tem sido amplamente estudada, especialmente pelo
Publicado em: 2009
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2. Hidroxiapatita associada a gentamicina: um estudo da influencia da gelatina no meio da precipitação e do processo de secagem na inibição do crescimento bacteriano
Estudos demonstram que a hidroxiapatita, vem se destacando entre as biocerâmicas, pois apresenta excelente biocompatibilidade com a fase mineral do osso humano, de fórmula estequiométrica (Ca10(PO4)6(OH)2 ), com razão Ca/P igual a 1,67. Tem a capacidade de unir-se quimicamente com o tecido, o que a torna um material bioativo. Apesar da estrutura e propri
Publicado em: 2009
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3. Doseamento microbiológico de gentamicina por difusão em agar - proposta de delineamento experimental / Microbiological assay of gentamicin sulfate by agar diffusion - proposal of experimental design
Gentamicin is a broad-spectrum antibiotic complex produced by actinomycetes belonging to Micromonospora genus and classified among aminoglycoside antibiotics, used in the treatment of serious infections derived from Gram-negative microorganisms. Alterations of their antimicrobial activity not shown in chemical assays can be evaluated through microbiological
Publicado em: 2006
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4. Antibiotic-impregnated heart valve sewing rings for treatment and prophylaxis of bacterial endocarditis.
Prosthetic heart valve sewing rings were impregnated with gentamicin crobefat (EMD 46217), a poorly soluble gentamicin salt, gentamicin sulfate, and clindamycin palmitate to prevent early prosthetic endocarditis. MICs and MBCs of gentamicin and/or clindamycin were tested against several pathogens of early prosthetic endocarditis. The combination of gentamici
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5. Comparison Between the Polymyxins and Gentamicin in Preventing Endotoxin-Induced Intravascular Coagulation and Leukopenia
Three antimicrobial agents were evaluated as to their ability to neutralize the toxic effects of endotoxin in rabbits. These consisted of two cyclic polypeptides, polymyxin B sulfate and colymycin M (sodium colistimethate), and an aminoglycoside, gentamicin sulfate. Polymyxin B regularly prevented endotoxin-induced leukopenia, thrombocytopenia, and dissemina
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6. Evaluation of the In Vitro Activity of Tobramycin as Compared with That of Gentamicin Sulfate
The in vitro activity of tobramycin was quantitatively compared with that of gentamicin sulfate against 195 bacterial isolates from clinical material. Tobramycin was found to be twice as active as gentamicin against isolates of Pseudomonas aeruginosa. Conversely, gentamicin proved fourfold more active than tobramycin against isolates of Serratia marcescens.
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7. Interaction of Purulent Material with Antibiotics Used to Treat Pseudomonas Infections
To define factors contributing to the adverse prognosis of patients with gram-negative bacillemia and abscess formation, we studied the interaction between polymyxin B, colistin sulfate, gentamicin, or carbenicillin with purulent material. Carbenicillin activity was not significantly altered by incubation with pus. Equal volumes of antibiotic and purulent se
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8. Protective Effect of Cephalothin Against Gentamicin-Induced Nephrotoxicity in Rats
The possibility that the nephrotoxicity of gentamicin may be potentiated by the concomitant administration of cephalothin was examined in a rat model. Cephalothin given once daily in dosages up to 800 mg/kg per day for 10 days produced no renal damage. Gentamicin, at 6 to 50 mg/kg per day, caused pathological changes which were dosage related and affected pr
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9. Medium-Dependent Activity of Gentamicin Sulfate Against Enterococci
Routine disc diffusion susceptibility tests (Bauer-Kirby technique), employing 5% sheep blood-Mueller-Hinton agar and 10-μg gentamicin sulfate discs, disclosed that a significant number of clinical enterococcal isolates were sensitive to the antibiotic, as also revealed by the agar dilution technique. With few exceptions, the isolates proved resistant to th
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10. Antibacterial Activity of Gentamicin Sulfate in Tissue Culture
Gentamicin is a more effective in vitro bacterial inhibitor than combined penicillinstreptomycin, is nontoxic to tissue culture monolayers, and does not inhibit virus replication.
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11. Susceptibility of Pseudomonas aeruginosa to Gentamicin Sulfate In Vitro: Lack of Correlation Between Disc Diffusion and Broth Dilution Sensitivity Data
Seventy-eight of 420 clinical isolates of Pseudomonas aeruginosa yielded zones of inhibition of less than 12 mm in diameter around 10-μg discs of gentamicin sulfate when tested by the standardized Bauer-Kirby disc diffusion method. Of 153 strains chosen from these isolates, one strain (0.65%) required 25 μg of gentamicin per ml for inhibition; the remainde
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12. Neuromuscular blockade due to gentamicin sulfate.