Genetic Regulation
Mostrando 1-12 de 1910 artigos, teses e dissertações.
-
1. The impact of the genetic background in a patient with papillary thyroid cancer and familial adenomatous polyposis
SUMMARY Thyroid cancer is the most common endocrine malignancy, and papillary thyroid carcinoma (PTC) is the main subtype. The cribriform morular variant is a histological phenotype of PTC characterized by its relationship with familial adenomatous polyposis (FAP). Description of the case: We report the genetic assessment of a 20-year-old female patient diag
Archives of Endocrinology and Metabolism. Publicado em: 2022
-
2. A functional interaction between the CCR5 and CD34 molecules expressed in hematopoietic cells can support (or even promote) the development of cancer
Abstract Inflammation and angiogenesis are linked to the development of cancer since both can support the establishment of a tumor-prone microenvironment. The CCR5 is a major regulatory molecule involved in inflammation. The CD34 molecule is commonly described as a hematopoietic stem cell marker, and CD34+ cells are involved in the regulation of distinct phy
Hematol., Transfus. Cell Ther.. Publicado em: 2020-03
-
3. ANTARCTICA AND ABNJ IN THE ANTHROPOCENE: CHALLENGES TO THE SUSTAINABLE MANAGEMENT OF MARINE GENETIC RESOURCES?
Resumo A época do Antropoceno traz novos desafios relacionados à tecnologia para o manejo sustentável da biodiversidade, incluindo o acesso a recursos genéticos marinhos. Embora separados em duas agendas multilaterais, a Antártica e as áreas fora da jurisdição nacional são casos comparáveis, uma vez que a regulação das atividades de bioprospecç�
Ambient. soc.. Publicado em: 25/11/2019
-
4. Análise da morfologia urbana para maximização de geração de energia fotovoltaica no Belenzinho, em São Paulo
Resumo O artigo analisa os arranjos morfológicos urbanos condicionantes da geração de energia fotovoltaica, no bairro do Belenzinho, em São Paulo. Foi utilizado o software 3D Rhinoceros® com os plug-ins Grasshopper® e Diva® para modelar a variação isolada dos parâmetros urbanísticos e identificar parâmetros que maximizam ou minimizam a incidênci
Ambient. constr.. Publicado em: 03/10/2019
-
5. Gene expression profiling reveals upregulated FUT1 and MYBPC1 in children with pancreaticobiliary maljunction
Pancreaticobiliary maljunction (PBM) is associated with high risk of epithelial atypical growth and malignant transformation of the bile duct or gallbladder. However, overall changes in genetic expression have not been examined in children with PBM. Genome-wide expression was analyzed using peripheral blood samples from 10 children with PBM and 15 pediatric
Braz J Med Biol Res. Publicado em: 29/07/2019
-
6. Polymorphism in the interleukin-10 gene is associated with overactive bladder phenotype associated with HTLV-1 infection
Abstract INTRODUCTION Human T-cell lymphotropic virus type 1 (HTLV-1)-associated inflammatory diseases are not well understood; however, their clinical manifestations may be influenced by the host genetic background. METHODS We genotyped 298 individuals with HTLV-1 and 380 controls for interleukin-10 (IL10) gene variants-rs3024496, rs1800871, rs1800896-a
Rev. Soc. Bras. Med. Trop.. Publicado em: 30/05/2019
-
7. Linear growth and bone metabolism in pediatric patients with inflammatory bowel disease
Resumo Objetivo: Revisar a fisiopatologia e os métodos de avaliação do crescimento linear e densidade mineral óssea em crianças e adolescentes com diagnóstico de doença inflamatória intestinal. Fontes dos dados: Revisão narrativa a partir de pesquisa nas bases de dados PubMed e Scopus por meio de busca ativa dos termos inflammatory bowel disease,
J. Pediatr. (Rio J.). Publicado em: 18/04/2019
-
8. Transcriptome sequencing and expression profiling of genes involved in the response to abiotic stress in Medicago ruthenica
Abstract Medicago ruthenica is a perennial forage legume with the remarkable ability to survive under unfavorable environmental conditions. It has been identified as an excellent species of Medicago that can adapt to various environmental stresses including low temperature, drought, and salinity. To investigate its potential as a genetic resource, we perform
Genet. Mol. Biol.. Publicado em: 28/06/2018
-
9. Role of non-coding RNAs in non-aging-related neurological disorders
Protein coding sequences represent only 2% of the human genome. Recent advances have demonstrated that a significant portion of the genome is actively transcribed as non-coding RNA molecules. These non-coding RNAs are emerging as key players in the regulation of biological processes, and act as "fine-tuners" of gene expression. Neurological disorders are cau
Braz J Med Biol Res. Publicado em: 11/06/2018
-
10. Sleep quality and OPRM1 polymorphisms: a cross-sectional study among opioid-naive individuals
ABSTRACT Opioidergic system involves in regulation of sleep and wakefulness. It is possible, therefore, that genetic polymorphisms in OPRM1 influence sleep quality. This study investigated the association of OPRM1 polymorphisms with subjective sleep quality among opioid-naive individuals. This cross-sectional observational study involved 161 opioid-naive mal
Braz. J. Pharm. Sci.. Publicado em: 07/06/2018
-
11. The role of ClpX in erythropoietic protoporphyria
ABSTRACT Hemoglobin is an essential biological component of human physiology and its production in red blood cells relies upon proper biosynthesis of heme and globin protein. Disruption in the synthesis of these precursors accounts for a number of human blood disorders found in patients. Mutations in genes encoding heme biosynthesis enzymes are associated wi
Hematol., Transfus. Cell Ther.. Publicado em: 2018-06
-
12. Transcriptome sequencing analysis of alfalfa reveals CBF genes potentially playing important roles in response to freezing stress
Abstract Alfalfa (Medicago sativa L.) is an important perennial forage, with high nutritional value, which is widely grown in the world. Because of low freezing tolerance, its distribution and production are threatened and limited by winter weather. To understand the complex regulation mechanisms of freezing tolerance in alfalfa, we performed transcriptome s
Genet. Mol. Biol.. Publicado em: 06/11/2017