Genetic Mapping
Mostrando 1-12 de 1813 artigos, teses e dissertações.
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1. Gene panel for the diagnosis of epidermolysis bullosa: proposal for a viable and efficient approach,
Abstract Background: Epidermolysis bullosa is characterized by cutaneous fragility and blistering. Historically, diagnosis is achieved by immunofluorescence mapping or transmission electron microscopy, both involving biopsy procedures. Genetic analysis, especially through next-generation sequencing, is an important tool for the diagnosis of this disease. In
An. Bras. Dermatol.. Publicado em: 2021-03
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2. Anais Brasileiros de Dermatologia: 2016-2020 Administration. Actions and acknowledgements
Abstract Background: Epidermolysis bullosa is characterized by cutaneous fragility and blistering. Historically, diagnosis is achieved by immunofluorescence mapping or transmission electron microscopy, both involving biopsy procedures. Genetic analysis, especially through next-generation sequencing, is an important tool for the diagnosis of this disease. In
An. Bras. Dermatol.. Publicado em: 2021-03
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3. Mapeamento genético laboral: prospecção axiológica, bioética e legislação brasileira
Resumo Objetiva-se comparar o estado da legislação brasileira sobre mapeamento genético com o de legislações internacionais visando dimensionar a realidade normativa do país quanto às tendências sociais de reconhecimento das diferenças e a abertura jurídica prospectiva, com foco na área laboral. Trata-se de revisão de literatura e pesquisa docume
Rev. Bioét.. Publicado em: 10/01/2020
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4. Mapping of QTL for total spikelet number per spike on chromosome 2D in wheat using a high-density genetic map
Abstract Total spikelet number per spike (TSS) is one of the key components of grain yield in wheat. Chromosome (chr.) 2D contains numerous genes that control TSS. In this study, we evaluated 138 F8 recombinant inbred lines (RILs) derived from an F2 population of a synthetic hexaploid wheat line (SHW-L1) and a common wheat cultivar (Chuanmai 32) for TSS in s
Genet. Mol. Biol.. Publicado em: 14/11/2019
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5. Genetic linkage map and mapping of the locus of biological nitrogen fixation inefficiency in cowpea
ABSTRACT. The objectives of the present study were to construct a cowpea genetic map using the F2 population resulting from the cross IC-1 x BRS Marataoã, based on single nucleotide polymorphism (SNP) markers, and to map the cpi gene, with additional reference to introgression with the consensus map of species, aiming to identify markers for assisted select
Acta Sci., Agron.. Publicado em: 23/09/2019
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6. Association mapping of drought tolerance indices in wheat: QTL-rich regions on chromosome 4A
ABSTRACT Drought is likely the main abiotic stress that affects wheat yield. The identification of drought-tolerant genotypes represents an effective way of dealing with the continuous decrease in water resources as well as the increase in world population. The aim of this study was to identify single nucleotide polymorphisms (SNP) associated with drought to
Sci. agric. (Piracicaba, Braz.). Publicado em: 02/09/2019
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7. ENDOPHYTIC FUNGI FROM THE BRAZILIAN FLORA AND THEIR EMPLOYMENT IN BIOTRANSFORMATION REACTIONS
The biotransformation reactions are used as a successful alternative to derivatization by the traditional chemistry because they conduct to uncommon reactions, which would hardly be carried out by chemical synthesis. A wide diversity of compounds may be metabolized by fungi, leading to chemical derivatives through selective reactions that work under ecofrien
Quím. Nova. Publicado em: 26/08/2019
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8. Association mapping in common bean revealed regions associated with Anthracnose and Angular Leaf Spot resistance
ABSTRACT: Despite important biotic stresses to common bean, Anthracnose (ANT) and Angular Leaf Spot (ALS) can cause losses of up to 80 % and occur in more than 60 countries around the world. Genetic resistance is the most sustainable strategy to manage these diseases. Thus, we aimed to (1) identify new SNP markers associated with ALS and ANT resistance loci
Sci. agric. (Piracicaba, Braz.). Publicado em: 2019-07
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9. Linkage disequilibrium and past effective population size in native Tunisian cattle
Abstract To carry out effective genome-wide association studies, information about linkage disequilibrium (LD) is essential. Here, we used medium-density SNP chips to provide estimates of LD in native Tunisian cattle. The two measures of LD that were used, mean r2 and D’, decreased from 0.26 to 0.05 and from 0.73 to 0.40, respectively, when the distance be
Genet. Mol. Biol.. Publicado em: 18/02/2019
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10. Association study of AFF1 rs340630 polymorphism with genetic susceptibility to rheumatoid arthritis in Chinese population
This study was performed to examine whether the AF4/FMR2 family, member 1 (AFF1) rs340630 polymorphism is involved in the genetic background of rheumatoid arthritis (RA) in a Chinese population. Two different study groups of RA patients and controls (328 RA patients and 449 healthy controls in the first study group; 232 RA patients and 313 controls in the se
Braz J Med Biol Res. Publicado em: 17/05/2018
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11. Growth hormone deficiency with advanced bone age: phenotypic interaction between GHRH receptor and CYP21A2 mutations diagnosed by sanger and whole exome sequencing
SUMMARY Isolated growth hormone deficiency (IGHD) is the most common pituitary hormone deficiency and, clinically, patients have delayed bone age. High sequence similarity between CYP21A2 gene and CYP21A1P pseudogene poses difficulties for exome sequencing interpretation. A 7.5 year-old boy born to second-degree cousins presented with severe short stature (h
Arch. Endocrinol. Metab.. Publicado em: 2017-12
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12. Mapping QTLs for drought tolerance in a SEA 5 x AND 277 common bean cross with SSRs and SNP markers
Abstract The common bean is characterized by high sensitivity to drought and low productivity. Breeding for drought resistance in this species involves genes of different genetic groups. In this work, we used a SEA 5 x AND 277 cross to map quantitative trait loci associated with drought tolerance in order to assess the factors that determine the magnitude of
Genet. Mol. Biol.. Publicado em: 23/10/2017