Genetic Effect
Mostrando 1-12 de 2781 artigos, teses e dissertações.
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1. O transtorno depressivo pode ser geneticamente herdado?
Sobre os fatores genéticos da depressão, a herdabilidade da depressão ainda não é consenso na literatura cientifica. No entanto, segundo alguns estudos estima-se que 37% dos casos possam ter uma relação genética, mesmo que essas relações sejam posteriormente moduladas pelo ambiente – ou seja, embora os genes possam ser relevantes para o surgim
Núcleo de Telessaúde Mato Grosso do Sul. Publicado em: 12/06/2023
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2. The effect of alpha-2A adrenergic receptor (ADRA2A) genetic polymorphisms on the depth of sedation of dexmedetomidine: a genetic observational pilot study
Abstract Background: The genetic polymorphisms of the alpha-2A adrenergic receptor (ADRA2A), which plays a significant role in sedation, anxiety relief, and antinociception, particularly in dexmedetomidine, may differ in the degree of sedation. This study aimed to investigate the effect of the genetic polymorphisms of ADRA2A (rs11195418, rs1800544, rs248451
Brazilian Journal of Anesthesiology. Publicado em: 2022
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3. Cushing disease due to a somatic USP8 mutation in a patient with evolving pituitary hormone deficiencies due to a germline GH1 splicing variant
SUMMARY We present the unique case of an adult Brazilian woman with severe short stature due to growth hormone deficiency with a heterozygous G to T substitution in the donor splice site of intron 3 of the growth hormone 1 (GH1) gene (c.291+1G>T). In this autosomal dominant form of growth hormone deficiency (type II), exon 3 skipping results in expression of
Archives of Endocrinology and Metabolism. Publicado em: 2022
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4. A meta-analysis: association between Beta-2 adrenergic receptor Arg16Gly polymorphism and asthma in China
Abstract For different populations, the association studies between the beta-2 adrenergic receptor (ADRB2) Arg16Gly mutation and asthma are conflict. This study was designated to evaluate ADRB2 Arg16Gly polymorphism and asthma in Chinese population. Systemic assessment was performed based on the data from PubMed, Embase, Web of Science, the Cochrane Library,
Food Sci. Technol. Publicado em: 2021-09
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5. Interstitial lung disease due to anti-TNF use in the treatment of psoriasis
Abstract Psoriasis is a chronic inflammatory disease that affects the skin variably, according to genetic and environmental factors. Some patients may benefit from systemic treatment with immunobiological agents, drugs that can be accompanied by several adverse effects. A case of a 58-year-old patient undergoing treatment for psoriasis with adalimumab for fi
An. Bras. Dermatol.. Publicado em: 2021-08
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6. BDNF Val66Met polymorphism and resilience in major depressive disorder: the impact of cognitive psychotherapy
Objective: Clinical and biological correlates of resilience in major depressive disorder are scarce. We aimed to investigate the effect of the Val66Met polymorphism in the BDNF gene on resilience scores in major depressive disorder patients and evaluate the polymorphism’s moderation effect on resilience scores in response to cognitive therapy. Method: A
Braz. J. Psychiatry. Publicado em: 2021-02
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7. EVALUATION OF DIVERSITY AND GENETIC STRUCTURE AS STRATEGIES FOR CONSERVATION OF NATURAL POPULATIONS OF Dalbergia nigra (Vell.) Allemão ex Benth.
ABSTRACT: The evaluation of diversity and genetic structure allows us to verify with precision the effect of evolutionary and anthropic processes on species. The objective of this research was to evaluate the divergence and the genetic structure of two natural populations of Dalbergia nigra, using molecular markers Inter Simple Sequence Repeats (ISSR). Leaf
CERNE. Publicado em: 2020-12
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8. ACCURACY OF GENETIC PARAMETERS ESTIMATION AND PREDICTION OF GENOTYPIC VALUES IN EUCALYPTUS USING DIFFERENT PLOT TYPES
ABSTRACT A suitable experimental design should control the environmental effect and be capable of discriminating genotypes. Two clonal tests of Eucalyptus were planted side by side in a randomized block design with the same 32 treatments under two different plot designs. The first trial was designed with five plants per plot (linear plot, LP) and six block r
CERNE. Publicado em: 2020-12
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9. Antidepressants, genetic risk, and the prevention of bipolar disorder
Abstract Objective: To understand the current evidence and guidelines behind the appropriate management of cardiac tumours. Methods: A comprehensive electronic literature search has been performed in major databases - PubMed, Embase, Scopus, Ovid, and Google Scholar. All articles that discussed all different forms of cardiac tumours, their clinical present
Braz. J. Psychiatry. Publicado em: 2020-10
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10. EFEITOS DA CANOAGEM NAS HABILIDADES MOTORAS DE CRIANÇAS E ADOLESCENTES COM SÍNDROME DE DOWN
RESUMO Introduction Down syndrome (DS) is a genetic condition characterized by an inadequate numerical distribution in chromosome pairing, with extra genetic material related to pair 21 leading to alterations that affect the development of several motor components. Objective To analyze the effects of kayak training for eight weeks on the gross motor skills
Rev Bras Med Esporte. Publicado em: 2020-08
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11. ASPECTOS REPRODUTIVOS E DESEMPENHO DE DIFERENTES LINHAGENS DE MATRIZES DE CODORNAS JAPONESAS
Resumo Objetivou-se avaliar parâmetros reprodutivos e o desempenho de diferentes grupos genéticos de codornas japonesas com diferentes pesos iniciais de produção. O delineamento experimental utilizado para os dados de desempenho zootécnico das aves foi inteiramente casualizado, com esquema fatorial 3 x 2 (três linhagens: UEM1, UEM2 e Comercial (COM), e
Ciênc. anim. bras.. Publicado em: 13/12/2019
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12. How history and geography may explain the distribution in the Comorian archipelago of a novel mutation in DNA repair-deficient xeroderma pigmentosum patients
Abstract Xeroderma pigmentosum (XP) is a rare, genetic, autosomal nucleotide excision repair-deficient disease characterized by sun-sensitivity and early appearance of skin and ocular tumors. Thirty-two black-skinned XP from Comoros, located in the Indian Ocean, were counted, rendering this area the highest world prevalence of XP. These patients exhibited a
Genet. Mol. Biol.. Publicado em: 13/12/2019