Gene Action
Mostrando 1-12 de 2500 artigos, teses e dissertações.
-
1. COMBINING ABILITY AND GENE ACTION IN THE EXPRESSION TRAITS IN MAXIXE
RESUMO O maxixe (Cucumis anguria L.) é uma espécie de origem africana, pertencente à família das cucurbitáceas, muito cultivado no Brasil, porém com pouca informação sobre o controle gênico das características. Efeitos gênicos aditivos, refletidos nas estimativas dos efeitos de variedade ou desempenho “per se” é importante na expressão das c
Revista Caatinga. Publicado em: 2022
-
2. Icariin stimulates differentiation of bone marrow-derived mesenchymal stem cells (BM-MSCs) through activation of cAMP/PKA/CREB
Icariin, a prenylated flavonol glycoside isolated from Epimedium, has been considered as a potential alternative therapy for osteoporosis. The present study aimed to clarify the detailed molecular mechanisms of action of icariin on osteoblast function, using bone marrow-derived mesenchymal stem cells (BM-MSCs). BM-MSCs were first stimulated by icariin. Then,
Braz. J. Pharm. Sci.. Publicado em: 20/12/2019
-
3. New tools for cell reprogramming and conversion: Possible applications to livestock
Abstract Somatic cell nuclear transfer and iPS are both forms of radical cell reprogramming able to transform a fully differentiated cell type into a totipotent or pluripotent cell. Both processes, however, are hampered by low efficiency and, in the case of iPS, the application to livestock species is uncertain. Epigenetic manipulation has recently emerged a
Anim. Reprod.. Publicado em: 28/11/2019
-
4. Novel homozygous mutation in a colombian patient with persistent müllerian duct syndrome: expanded phenotype
ABSTRACT The anti-Müllerian hormone triggers the regression of uterus and fallopian tubes in male embryos; if there are problems in the synthesis or action of this protein, Müllerian structures persist in an otherwise phenotypic male. The most frequent clinical presentation of Persistent Mullerian Duct syndrome is cryptorchidism and inguinal hernia. The fe
Int. braz j urol.. Publicado em: 07/11/2019
-
5. Partial diallel and potential of super sweet corn inbred lines bt 2 to obtain hybrids
RESUMO Os objetivos foram determinar o potencial de linhagens S4 de milho superdoce para síntese de híbridos, identificar os tipos de ações gênicas predominantes e as correlações para diferentes caracteres importantes para o melhoramento. Os 81 híbridos obtidos em um dialelo parcial 9x9 e três testemunhas foram avaliados em blocos completos casualiz
Hortic. Bras.. Publicado em: 07/11/2019
-
6. Modulatory effects of neuropeptides on pentylenetetrazol-induced epileptic seizures and neuroinflammation in rats
RESUMO OBJETIVO Nosso objetivo foi explorar os efeitos dos neuropeptídeos grelina, obestatina e peptídeo intestinal vasoativo (VIP) nas convulsões e concentrações plasmáticas de biomarcadores neuroinflamatórios, incluindo peptídeo relacionado ao gene da calcitonina (CGRP), substância-P (SP) e interleucina-1 beta (IL-1β) em convulsões induzidas p
Rev. Assoc. Med. Bras.. Publicado em: 10/10/2019
-
7. Diallel analysis and heterosis components in paprika peppers
RESUMO O objetivo deste estudo foi quantificar e avaliar os componentes da heterose em híbridos de páprica para produtividade, teor de capsanteno (graus ASTA) e resistência a Phytophthora capsici, e identificar as linhagens parentais elevada capacidade geral de combinação (CGC) para serem utilizados em futuros programas de melhoramento e/ou para obter n
Rev. Ciênc. Agron.. Publicado em: 2019-06
-
8. Protective effect of Schisandra chinensis total lignans on acute alcoholic-induced liver injury related to inhibiting CYP2E1 activation and activating the Nrf2/ARE signaling pathway
ABSTRACT Schisandra chinensis (Turcz.) Baill., Schisandraceae, is a well-known traditional Chinese medicine used mainly as a recipe for hepatoprotection. Modern researches have revealed that the hepatoprotection is related to its lignans and crude polysaccharide. In this study, we examined the effect and mechanism of S. chinensis total lignans on the liver i
Rev. bras. farmacogn.. Publicado em: 27/05/2019
-
9. Triiodothyronine (T3) upregulates the expression of proto-oncogene TGFA independent of MAPK/ERK pathway activation in the human breast adenocarcinoma cell line, MCF7
ABSTRACT Objective: To verify the physiological action of triiodothyronine T3 on the expression of transforming growth factor α (TGFA) mRNA in MCF7 cells by inhibition of RNA Polymerase II and the MAPK/ERK pathway Materials and methods: The cell line was treated with T3 at a physiological dose (10−9M) for 10 minutes, 1 and 4 hour (h) in the presence or
Arch. Endocrinol. Metab.. Publicado em: 21/03/2019
-
10. Association of serum levels of C-reactive protein with CRP-717 T/C polymorphism and viremia in HCV and HBV carriers
Abstract INTRODUCTION: The present study investigated the association of the rs2794521 polymorphism in the CRP gene in individuals with chronic hepatitis B and C, correlating it with markers of hepatic inflammation, fibrosis scores, viral load, and plasma protein levels. METHODS: The study analyzed 185 blood samples obtained from patients with hepatitis B
Rev. Soc. Bras. Med. Trop.. Publicado em: 21/02/2019
-
11. Cytotoxic and pro-apoptotic action of MjTX-I, a phospholipase A2 isolated from Bothrops moojeni snake venom, towards leukemic cells
Abstract Background: Chronic myeloid leukemia (CML) is a BCR-ABL1+ myeloproliferative neoplasm marked by increased myeloproliferation and presence of leukemic cells resistant to apoptosis. The current first-line therapy for CML is administration of the tyrosine kinase inhibitors imatinib mesylate, dasatinib or nilotinib. Although effective to treat CML, som
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 24/01/2019
-
12. Genetic control of aluminum tolerance in tropical maize germplasm
ABSTRACT Aluminum (Al) toxicity is the most limiting factor to maize crop productivity in acid soils. Therefore, the understanding of inheritance of Al tolerance in maize is important for the developmentof more adequate procedures for Al tolerant genotypes selection. In this sense, the objectives of this study were to determine the inheritance, and the gener
Bragantia. Publicado em: 07/01/2019