Gamma Aminobutyric Acid
Mostrando 1-12 de 401 artigos, teses e dissertações.
-
1. O transtorno depressivo pode ser geneticamente herdado?
Sobre os fatores genéticos da depressão, a herdabilidade da depressão ainda não é consenso na literatura cientifica. No entanto, segundo alguns estudos estima-se que 37% dos casos possam ter uma relação genética, mesmo que essas relações sejam posteriormente moduladas pelo ambiente – ou seja, embora os genes possam ser relevantes para o surgim
Núcleo de Telessaúde Mato Grosso do Sul. Publicado em: 12/06/2023
-
2. Screening and characterisation of gamma-aminobutyric acid (GABA) producing lactic acid bacteria isolated from Thai fermented fish (Plaa-som) in Nong Khai and its application in Thai fermented vegetables (Som-pak)
Abstract This study aimed to evaluate the capability of lactic acid bacteria (LAB) isolated from different kinds of fermented fish products (Plaa-som) on the production of γ-aminobutyric acid (GABA). Among them, isolate L10-11, identified as Lactobacillus plantarum, offered the highest GABA production and was selected for further study. The highest producti
Food Sci. Technol. Publicado em: 2020-06
-
3. Screening and characterisation of gamma-aminobutyric acid (GABA) producing lactic acid bacteria isolated from Thai fermented fish (Plaa-som) in Nong Khai and its application in Thai fermented vegetables (Som-pak)
Abstract This study aimed to evaluate the capability of lactic acid bacteria (LAB) isolated from different kinds of fermented fish products (Plaa-som) on the production of γ-aminobutyric acid (GABA). Among them, isolate L10-11, identified as Lactobacillus plantarum, offered the highest GABA production and was selected for further study. The highest producti
Food Sci. Technol. Publicado em: 28/11/2019
-
4. Sedative and muscle relaxant activities of diterpenoids from Phlomidoschema parviflorum
Abstract Phlomidoschema parviflorum (Benth.) Vved. (Basionym: Stachys parviflora Benth.) Lamiaceae, have significance medicinal importance as it is used in number of health disorders including diarrhea, fever, sore mouth and throat, internal bleeding, weaknesses of the liver and heart genital tumors, sclerosis of the spleen, inflammatory tumors and cancerous
Rev. bras. farmacogn.. Publicado em: 2017-10
-
5. GABA (γ-aminobutyric acid) production, antioxidant activity in some germinated dietary seeds and the effect of cooking on their GABA content
Abstract Germinated grains have been known as sources of Gamma-aminobutyric acid (GABA) that provide beneficial effects for human health. This study was aimed to investigate GABA production, dietary fiber, antioxidant activity, and the effect of cooking on GABA loss in germinated legumes and sesame. The highest GABA content was found in germinated mung bean,
Food Sci. Technol. Publicado em: 29/04/2016
-
6. Involvement of GABAergic pathway in the sedative activity of apigenin, the main flavonoid from Passiflora quadrangularis pericarp
Abstract In the current study we showed that oral administration of an aqueous extract of Passiflora quadrangularis L., Passifloraceae, pericarp results in a significant prolongation of the sleep duration in mice evaluated in the ethyl ether-induced hypnosis test which indicates sedative effects. Apigenin, the main flavonoid of the extract, induced a similar
Rev. bras. farmacogn.. Publicado em: 2015-04
-
7. Panic-like defensive behavior but not fear-induced antinociception is differently organized by dorsomedial and posterior hypothalamic nuclei of Rattus norvegicus (Rodentia, Muridae)
The hypothalamus is a forebrain structure critically involved in the organization of defensive responses to aversive stimuli. Gamma-aminobutyric acid (GABA)ergic dysfunction in dorsomedial and posterior hypothalamic nuclei is implicated in the origin of panic-like defensive behavior, as well as in pain modulation. The present study was conducted to test the
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-04
-
8. Neurotransmitter evaluation in the hippocampus of rats after intracerebral injection of TsTX scorpion toxin
TsTX is an α-type sodium channel toxin that stimulates the discharge of neurotransmitters from neurons. In the present study we investigated which neurotransmitters are released in the hippocampus after TsTX injection and if they are responsible for electrographic or histopathological effects. Microdialysis revealed that the toxin increased glutamate extrac
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2009
-
9. Interferência da moxidectina na motivação sexual e ereção peniana de ratos: envolvimento de neurotransmissores hipotalâmicos e estriatais / Moxidectin interference on sexual motivation and penile erection: involvement of hypothalamic and striatal neurotransmitters
A moxidectina (MOX) é um antiparasitário utilizado na clínica veterinária. Em mamíferos seu mecanismo de ação envolve o ácido ?-aminobutírico (GABA), um neurotransmissor que tem papel relevante na regulação dos comportamentos sexual e motor. Dados anteriores por nós obtidos mostraram que a MOX prejudicou o comportamento sexual e a coordenação m
Publicado em: 2007
-
10. Effect of the GABA B agonist baclofen on dipyrone-induced delayed gastric emptying in rats
Dipyrone administered intravenously (iv) or intracerebroventricularly (icv) delays gastric emptying (GE) in rats. Gamma-aminobutyric acid (GABA) is the most potent inhibitory neurotransmitter of the central nervous system. The objective of the present study was to determine the effect of icv baclofen, a GABA B receptor agonist, on delayed GE induced by dipyr
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-01
-
11. Study of the gamma-aminobutyric acid type A receptor alpha-1 subunit gene (GABRA1) and electroencephalographic analysis in girls with gonadotropin-dependent precocious puberty / Estudo do gene da subunidade alfa-1 do receptor tipo A do ácido gama-aminobutírico (GABRA1) e avaliação eletroencefalográfica em meninas com puberdade precoce dependente de gonadotrofinas
O ácido gama-aminobutírico (GABA), principal neurotransmissor inibitório, está envolvido no mecanismo intrínseco do início da puberdade. Os efeitos inibitórios do GABA sobre a secreção de GnRH (hormônio hipotalâmico estimulador da secreção das gonadotrofinas) são mediados pelo receptor tipo A (GABAA) que é composto por diferentes subunidades o
Publicado em: 2005
-
12. Cardiovascular responses to microinjections of GABA or anesthetics into the rostral ventrolateral medulla of conscious and anesthetized rats
The rostral ventrolateral medulla (RVLM) contains neurons involved in tonic and reflex control of arterial pressure. We describe the effects of gamma-aminobutyric acid (GABA) and anesthetics injected into the RVLM of conscious and urethane (1.2 g/kg, iv) anesthetized Wistar rats (300-350 g). In conscious rats, bilateral microinjection of GABA (50 nmol/200 nl
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-09