Fruitfly
Mostrando 13-24 de 31 artigos, teses e dissertações.
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13. Conserved function of anopheles gambiae midgut-specific promoters in the fruitfly.
Control of malaria by a methodology that would permit the effective blockage of the Anopheles gambiae midgut wall penetration by Plasmodium parasites requires a detailed understanding of both the physiology of the mosquito's digestion, and of the interactions between the parasite and its host. We have transformed Drosophila melanogaster with several construc
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14. Functional similarity in appendage specification by the Ultrabithorax and abdominal-A Drosophila HOX genes.
In Drosophila, the Ultrabithorax, abdominal-A and Abdominal-B HOX genes of the bithorax complex determine the identity of part of the thorax and the whole abdomen. Either the absence of these genes or their ectopic expression transform segments into the identity of different ones along the antero-posterior axis. Here we show that misexpression of Ultrabithor
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15. A protein product of the Drosophila recessive tumor gene, l (2) giant gl, potentially has cell adhesion properties
In the fruitfly Drosophila melanogaster the recessive mutation lethal (2) giant larvae affects cell growth and cell adhesion properties of neural and imaginal disc cells during embryonic and larval development. Here we report the nucleotide sequence of a cDNA from one of the two major transcripts of the l (2) gl gene containing a 3.5-kb open reading frame. F
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16. RNA-binding proteins and circadian rhythms in Arabidopsis thaliana.
An Arabidopsis transcript preferentially expressed at the end of the daily light period codes for the RNA-binding protein AtGRP7. A reverse genetic approach in Arabidopsis thaliana has revealed its role in the generation of circadian rhythmicity: AtGRP7 is part of a negative feedback loop through which it influences the oscillations of its own transcript. Bi
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17. Flies, clocks and evolution.
The negative feedback model for gene regulation of the circadian mechanism is described for the fruitfly, Drosophila melanogaster. The conservation of function of clock molecules is illustrated by comparison with the mammalian circadian system, and the apparent swapping of roles between various canonical clock gene components is highlighted. The role of cloc
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18. Dosage Compensation Regulatory Proteins and the Evolution of Sex Chromosomes in Drosophila
In the fruitfly Drosophila melanogaster, the four male-specific lethal (msl) genes are required to achieve dosage compensation of the male X chromosome. The MSL proteins are thought to interact with cis-acting sites that confer dosage compensation to nearby genes, as they are detected at hundreds of discrete sites along the length of the polytene X chromosom
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19. Genome-wide analysis of the Drosophila immune response by using oligonucleotide microarrays
To identify new Drosophila genes involved in the immune response, we monitored the gene expression profile of adult flies in response to microbial infection by using high-density oligonucleotide microarrays encompassing nearly the full Drosophila genome. Of 13,197 genes tested, we have characterized 230 induced and 170 repressed by microbial infection, most
The National Academy of Sciences.
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20. Vacuolar-type proton pumps in insect epithelia
Active transepithelial cation transport in insects was initially discovered in Malpighian tubules, and was subsequently also found in other epithelia such as salivary glands, labial glands, midgut and sensory sensilla. Today it appears to be established that the cation pump is a two-component system of a H+-transporting V-ATPase and a cation/nH+ antiport
Company of Biologists.
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21. Ordered Partitioning Reveals Extended Splice-Site Consensus Information
Using recently available cDNA and genomic data (Berkeley Drosophila Genome Project; http://www.fruitfly.org), we computed a large sample of 10,057 Drosophila splice sites. An information-theoretic analysis of the nucleotide sequences adjacent to these splice sites showed a strong correlation between the sizes of introns and exons and the levels of informatio
Cold Spring Harbor Laboratory Press.
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22. A Physical Map of the X Chromosome of Drosophila Melanogaster: Cosmid Contigs and Sequence Tagged Sites
A physical map of the euchromatic X chromosome of Drosophila melanogaster has been constructed by assembling contiguous arrays of cosmids that were selected by screening a library with DNA isolated from microamplified chromosomal divisions. This map, consisting of 893 cosmids, covers ~64% of the euchromatic part of the chromosome. In addition, 568 sequence t
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23. euGenes: a eukaryote genome information system
euGenes is a genome information system and database that provides a common summary of eukaryote genes and genomes, at http://iubio.bio.indiana.edu/eugenes/. Seven popular genomes are included: human, mouse, fruitfly, Caenorhabditis elegans worm, Saccharomyces yeast, Arabidopsis mustard weed and zebrafish, with more planned. This information, automatically ex
Oxford University Press.
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24. SilkDB: a knowledgebase for silkworm biology and genomics
The Silkworm Knowledgebase (SilkDB) is a web-based repository for the curation, integration and study of silkworm genetic and genomic data. With the recent accomplishment of a ∼6X draft genome sequence of the domestic silkworm (Bombyx mori), SilkDB provides an integrated representation of the large-scale, genome-wide sequence assembly, cDNAs, clusters of e
Oxford University Press.