Free Radical Reactions
Mostrando 13-24 de 52 artigos, teses e dissertações.
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13. The role of chemokines and chemokine receptors in eosinophil activation during inflammatory allergic reactions
Chemokines are important chemotactic cytokines that play a fundamental role in the trafficking of leukocytes to sites of inflammation. They are also potent cell-activating factors, inducing cytokine and histamine release and free radical production, a fact that makes them particularly important in the pathogenesis of allergic inflammation. The action of chem
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-11
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14. PeroxidaÃÃo lipÃdica em pacientes esquistossomÃticos esplenectomizados da zona da mata e em ratos submetidos à Dieta BÃsica Regional (DBR)
The aim of this study was to investigate the oxidative stress in plasma and erytrhocytes from schistossomiasis mansoni patients subjected to clinical and splenectomy treatment associated with auto-implantation of spleen tissue, as well as, in young rats fed with a Regional Basic Diet (RBD) which has been used in the sugarcane rural area of Pernambuco state.
Publicado em: 2003
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15. The aging process.
Aging is the progressive accumulation of changes with time that are associated with or responsible for the ever-increasing susceptibility to disease and death which accompanies advancing age. These time-related changes are attributed to the aging process. The nature of the aging process has been the subject of considerable speculation. Accumulating evidence
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16. Free-radical reactions induced by OH-radical attack on cytosine-related compounds: a study by a method combining ESR, spin trapping and HPLC.
Free-radical reactions induced by OH-radical attack on cytosine-related compounds were investigated by a method combining ESR, spin trapping with 2-methyl-2-nitrosopropane and high-performance liquid chromatography (HPLC). Cytidine, 2'-deoxycytidine, cytidine 3'-monophosphate, cytidine 5'-monophosphate, 2'-deoxycytidine 5'-monophosphate and their derivatives
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17. Direct evidence that oxygen-derived free radicals contribute to postischemic myocardial dysfunction in the intact dog.
Electron paramagnetic resonance (EPR) spectroscopy was used to investigate whether (i) the free radicals produced in the "stunned" myocardium (myocardium with postischemic contractile dysfunction) are derived from O2, (ii) inhibition of radical reactions improves function, and (iii) i.v. spin traps are effective. Open-chest dogs undergoing a 15-min coronary
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18. Neurovascular dysfunction in diabetic rats. Potential contribution of autoxidation and free radicals examined using transition metal chelating agents.
Oxygen free radical activity is elevated in diabetes mellitus and has been implicated in the etiology of vascular complications. Recent studies have shown that impaired perfusion of nerve endoneurium is a major cause of nerve fiber dysfunction in experimental diabetes. Free radical scavenger treatment prevents the development of nerve conduction abnormalitie
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19. Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain.
Free radical-mediated oxidative damage has been implicated in tissue injury resulting from ischemia/reperfusion events. Global cortical ischemia/reperfusion injury to Mongolian gerbil brains was produced by transient occlusion of both common carotid arteries. Protein oxidation, as measured by protein carbonyl content, increased significantly during the reper
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20. Organ chemiluminescence: noninvasive assay for oxidative radical reactions.
In situ and perfused rat livers showed a spontaneous chemiluminescence of 7-12 counts/sec . cm2 (corresponding to 7-12 x 10(3) photons/sec . cm2); chemiluminescence was increased up to 30 times by infusion of exogenous hydroperoxides. The chemiluminescence of the perfused liver was oxygen dependent. Ethyl, t-butyl, and cumene hydroperoxides were almost equal
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21. Adverse health effects of PM10 particles: involvement of iron in generation of hydroxyl radical.
OBJECTIVES: Environmental particles < 10 microns average aerodynamic diameter (PM10) are associated with mortality, exacerbation of airways diseases, and decrement in lung function. It is hypothesised that PM10 particles, along with other pathogenic particles, generate free radicals at their surface in reactions involving iron, and that this is a factor in t
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22. Overexpression of Cu-Zn superoxide dismutase in Drosophila does not affect life-span.
Aging and disease processes may be due to deleterious and irreversible changes produced by free radical reactions. The enzyme copper-zinc superoxide dismutase (Cu-Zn SOD; superoxide:superoxide oxidoreductase, EC 1.15.1.1) performs a protective function by scavenging superoxide radicals. The Cu-Zn SOD gene (Sod) cloned from Drosophila melanogaster was introdu
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23. Nuclear Coupling of 33S and the Nature of Free Radicals in Irradiated Crystals of Cystine Dihydrochloride
The 33S hyperfine structure has been observed and analyzed in the electron spin resonance of γ-irradiated single crystals of cystine dihydrochloride at 77°K and at room temperature. The radicals observed at room temperature and previously assigned as RCH2S are proved to be disulfide radicals, RCH2SS. However, the RCH2S radical is identified by the 33S meas
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24. Electrophilic and free radical nitration of benzene and toluene with various nitrating agents*
Electrophilic nitration of toluene and benzene was studied under various conditions with several nitrating systems. It was found that high orthopara regioselectivity is prevalent in all reactions and is independent of the reactivity of the nitrating agent. The methyl group of toluene is predominantly ortho-para directing under all reaction conditions. Steric