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Mostrando 37-48 de 57 artigos, teses e dissertações.
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37. A review of psychiatric literature for residency training programs, 1980s.
The authors obtained cumulated reading lists from sixteen nationally-recognized psychiatric residency programs to assess the common body of knowledge shared by recent psychiatry graduates and learn which works in psychiatry had survived from an earlier compilation in 1964 (Woods, Pieper, and Frazier, "Basic Psychiatric Literature" [2]. The new list was compi
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38. Heart transplantation in an 8-month-old girl. 10th anniversary report.
In 1984, Dr. Denton A. Cooley led a surgical team that implanted a cardiac allograft in an 8-month-old girl who had end-stage cardiac disease secondary to endocardial fibroelastosis. At that time, experience with cardiac transplantation in infants was limited, and the long-term effects of the procedure were cause for concern. Ten years later, our patient is
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39. The HeartMate left ventricular assist system. Overview and 12-year experience.
Cardiac transplantation has become a widely accepted option for treating end-stage heart failure. As the waiting time for donor hearts grows, new generations of left ventricular assist systems are being developed for patients awaiting transplantation. Great strides have been made in the study and use of such devices, both as temporary support and (perhaps ul
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40. Interaction of Nerve Growth Factor with Surface Membranes: Biological Competence of Insolubilized Nerve Growth Factor
Nerve growth factor was insolubilized by covalent attachment to Sepharose beads. Nerve growth factor-Sepharose was biologically active in both the neurite outgrowth assay for nerve growth factor and in preserving responsive neurons in vitro. Modification of the bioassay to detect solubilized activity of nerve growth factor and histological examination of gan
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41. First Clinical Use of the Redesigned HeartMate® II Left Ventricular Assist System in the United States: A Case Report
Axial flow ventricular assist devices show great promise as a potential treatment for patients with end-stage heart failure. The HeartMat® II system, redesigned on the basis of initial clinical experiences in Europe, is now in clinical trials in the United States. We report on the 1st use of the newly redesigned HeartMate II in the United States. The system
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42. Transmyocardial laser revascularization. Does it have a role in the treatment of ischemic heart disease?
Transmyocardial laser revascularization, with or without coronary artery bypass grafting, is an alternative modality for complete revascularization in selected patients with coronary artery disease. Arguably, this modality works by shunting left ventricular blood directly into the ischemic myocardium via laser-mediated transmural channels. In clinical trials
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43. Paracrystalline inclusions of a novel ferritin containing nonheme iron, produced by the human gastric pathogen Helicobacter pylori: evidence for a third class of ferritins.
An abundant 19.3-kDa Helicobacter pylori protein has been cloned, and the sequence is homologous with a ferritin-like protein produced by Escherichia coli K-12. Homologies are also present with a number of eucaryotic ferritins, as well as with the heme group-containing bacterioferritins. All amino acids involved in chelation of inorganic iron by ferritins fr
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44. Genetic Manipulation of Lactococcus lactis by Using Targeted Group II Introns: Generation of Stable Insertions without Selection
Despite their commercial importance, there are relatively few facile methods for genomic manipulation of the lactic acid bacteria. Here, the lactococcal group II intron, Ll.ltrB, was targeted to insert efficiently into genes encoding malate decarboxylase (mleS) and tetracycline resistance (tetM) within the Lactococcus lactis genome. Integrants were readily i
American Society for Microbiology.
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45. A null deficiency allele of alpha 1-antitrypsin, QOludwigshafen, with altered tertiary structure.
The most common deficiency allele of the plasma protease inhibitor alpha 1-antitrypsin (alpha 1AT) is PI*Z. Some rare deficiency alleles of alpha 1AT produce low but detectable amounts of plasma alpha 1AT (1-20% of normal), which can be differentiated by isoelectric focusing. Others, designated null (QO) alleles, produce no alpha 1AT detectable by routine qu
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46. Mechanism of Action of Nerve Growth Factor and Cyclic AMP on Neurite Outgrowth in Embryonic Chick Sensory Ganglia: Demonstration of Independent Pathways of Stimulation
The suggested role of adenosine 3′:5′-cyclic monophosphate as the “second messenger” in the neurite outgrowth from chick embryonic sensory ganglia mediated by nerve growth factor was examined. Although N6,O2-dibutyryl adenosine 3′:5′-cyclic monophosphate induces fiber outgrowth at concentrations of 1-5 mM, this response is morphologically distinc
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47. Mitochondria Use Different Mechanisms for Transport of Multispanning Membrane Proteins through the Intermembrane Space
The mitochondrial inner membrane contains numerous multispanning integral proteins. The precursors of these hydrophobic proteins are synthesized in the cytosol and therefore have to cross the mitochondrial outer membrane and intermembrane space to reach the inner membrane. While the import pathways of noncleavable multispanning proteins, such as the metaboli
American Society for Microbiology.
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48. The N-terminal propiece of interleukin 1α is a transforming nuclear oncoprotein
Interleukin 1α (IL-1α) is a pleiotropic cytokine involved in the immune response, inflammatory processes, and hematopoiesis, and acts as a mitogen for several malignant cell types, including acute leukemia and Kaposi sarcoma cells. These diverse activities have been exclusively attributed to the plasma membrane receptor-binding, 17-kDa C-terminal component
The National Academy of Sciences of the USA.